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Boehringer Ingelheim receives FDA Priority Review for afatinib to treat EGFR mutation-positive NSCLC

Boehringer Ingelheim today announced that the New Drug Application (NDA) for its investigational oncology compound afatinib has been accepted for filing and granted Priority Review by the U.S. Food and Drug Administration (FDA).

17 Jan 2013

Scientists determine structure of Ltn1 protein

Using an innovative approach, scientists at The Scripps Research Institute (TSRI) have determined the structure of Ltn1, a recently discovered "quality-control" protein that is found in the cells of all plants, fungi and animals.

17 Jan 2013

Scientists to investigate how cancer cells hide to avoid chemotherapy drugs

Scientists hope to improve leukaemia treatment by investigating how cancer cells use 'hiding places' in the body to avoid chemotherapy drugs.

17 Jan 2013

Report describes 2 brain underpinnings of emotion dysregulation in borderline personality disorder

Originally, the label "borderline personality disorder" was applied to patients who were thought to represent a middle ground between patients with neurotic and psychotic disorders. Increasingly, though, this area of research has focused on the heightened emotional reactivity observed in patients carrying this diagnosis, as well as the high rates with which they also meet diagnostic criteria for posttraumatic stress disorder and mood disorders.

17 Jan 2013

FDA approves InfraScan’s noninvasive handheld brain hematoma detector

InfraScan, a medical device company specializing in brain injury diagnostic products, announced today that it has obtained U.S. Food and Drug Administration approval to market the Infrascanner Model 2000, a noninvasive handheld brain hematoma detector.

17 Jan 2013

University of Hertfordshire to lead two new Govt-funded projects into dementia research

Researchers at the University of Hertfordshire are leading two of the twenty-one new Government-funded projects into dementia research - to boost dementia diagnosis rates and trial ground-breaking treatments, as well as helping people with dementia live well with the condition today.

17 Jan 2013

AVEO commences underwritten public offering of shares of common stock

AVEO Pharmaceuticals, Inc. today announced that it has commenced an underwritten public offering of shares of its common stock. All of the shares in the offering are to be sold by AVEO.

17 Jan 2013

Astellas announces FDA acceptance of Tarceva sNDA for EGFR activating mutation-positive NSCLC

Astellas Pharma US, Inc., a U.S. subsidiary of Tokyo-based Astellas Pharma Inc., today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing a supplemental New Drug Application (sNDA) for Tarceva (erlotinib) for first-line use in people with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) activating mutations.

17 Jan 2013

Top-line results from Amgen’s Aranesp Phase 3 trial on heart failure and anemia

Amgen today announced top-line results of the Phase 3 Aranesp (darbepoetin alfa) RED-HF (Reduction of Events With Darbepoetin Alfa in Heart Failure) Trial.

17 Jan 2013

New method based on mass sequencing can detect hereditary breast and ovarian cancer syndrome

Researchers of the Catalan Institute of Oncology (ICO) at the Bellvitge Biomedical Research Institute (IDIBELL) have developed and validated a new method to diagnose hereditary breast and ovarian cancer syndrome based on mass sequencing of BRCA1 and BRCA2 genes. The model is based on a genetic and bioinformatic analysis which has been proved very effective.

17 Jan 2013

Protein Sciences receives FDA approval for Flublok vaccine

The U.S. Food and Drug Administration today announced that it has approved Flublok, the first trivalent influenza vaccine made using an insect virus (baculovirus) expression system and recombinant DNA technology. Flublok is approved for the prevention of seasonal influenza in people 18 through 49 years of age.

16 Jan 2013

ARHGEF28 gene mutations present in amyotrophic lateral sclerosis: Research

Researchers at Western University in London, Canada, have identified a new genetic mutation for amyotrophic lateral sclerosis (ALS), opening the door to future targeted therapies. Dr. Michael Strong, a scientist with Western's Robarts Research Institute and Distinguished University Professor in Clinical Neurological Sciences at the Schulich School of Medicine & Dentistry, and colleagues found that mutations within the ARHGEF28 gene are present in ALS.

16 Jan 2013

Women with emotional exhaustion exhibit sound hypersensitivity when exposed to stress

Women suffering from stress-related exhaustion exhibit hypersensitivity to sounds when exposed to stress. In some cases, a sound level corresponding to a normal conversation can be perceived as painful. This according to a study from Karolinska Institutet and Stockholm University's Stress Research Institute in Sweden, which tested sensitivity to sounds immediately after a few minutes' artificially induced stress.

16 Jan 2013

Patients with COPD more likely to develop serious bacterial infections

It is well known that COPD patients run a higher risk of contracting respiratory infections. However, a new thesis from Lund University in Sweden shows that they are also at higher risk of other bacterial infections, such as tuberculosis (TB) and pneumococcal and staphylococcal infections that can cause serious illness.

16 Jan 2013

Viewpoints: N.Y. gun law could pose problems for health professionals; 'Jarring discrepancy' between medical costs and premium increases; State officials wage battle against health law

The broad gun control bill approved Tuesday by the New York Legislature substantially strengthens the state's gun control laws. ... Some sections of the law, however, were not fully vetted in the rush. One provision asks health care professionals - physicians, psychologists, registered nurses or licensed clinical social workers - to report to local health care officials when they have reason to believe that patients could harm themselves or others. ... The provision would seem to raise significant legal questions.

16 Jan 2013

Political cartoon: 'Paved Paradise?'

Kaiser Health News provides a fresh take on health policy developments with "Paved Paradise?" by Chip Bok.

16 Jan 2013

Some children with autism lose symptoms and diagnosis as they grow older

Some children who are accurately diagnosed in early childhood with autism lose the symptoms and the diagnosis as they grow older, a study supported by the National Institutes of Health has confirmed. The research team made the finding by carefully documenting a prior diagnosis of autism in a small group of school-age children and young adults with no current symptoms of the disorder.

16 Jan 2013

Medical News

Boehringer Ingelheim receives FDA Priority Review for afatinib to treat EGFR mutation-positive NSCLC

Scientists determine structure of Ltn1 protein

Scientists to investigate how cancer cells hide to avoid chemotherapy drugs

Report describes 2 brain underpinnings of emotion dysregulation in borderline personality disorder

FDA approves InfraScan’s noninvasive handheld brain hematoma detector

University of Hertfordshire to lead two new Govt-funded projects into dementia research

AVEO commences underwritten public offering of shares of common stock

Astellas announces FDA acceptance of Tarceva sNDA for EGFR activating mutation-positive NSCLC

Top-line results from Amgen’s Aranesp Phase 3 trial on heart failure and anemia

New method based on mass sequencing can detect hereditary breast and ovarian cancer syndrome

Protein Sciences receives FDA approval for Flublok vaccine

ARHGEF28 gene mutations present in amyotrophic lateral sclerosis: Research

Women with emotional exhaustion exhibit sound hypersensitivity when exposed to stress

Patients with COPD more likely to develop serious bacterial infections

Viewpoints: N.Y. gun law could pose problems for health professionals; 'Jarring discrepancy' between medical costs and premium increases; State officials wage battle against health law

Political cartoon: 'Paved Paradise?'

Some children with autism lose symptoms and diagnosis as they grow older

First Edition: January 16, 2013

Study identifies individual role of electrical heterogeneity and fibre structure in AF

Mental health advocates await final rule

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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