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Cedars-Sinai to include more patients in hypothermia plus clot-busting drug trial for stroke

An international multicenter clinical trial led by a Cedars-Sinai neurologist on the combination of brain cooling and "clot-busting" drug therapy after stroke has received Food and Drug Administration approval to expand from 50 patients to 400.

7 Feb 2013

Lannett second quarter net sales increase 32% to $36.6 million

Lannett Company, Inc. today reported continued strong momentum, with sharply improved financial results for its fiscal 2013 second quarter ended December 31, 2012, compared with the prior year period.

7 Feb 2013

Drug-carrying nanoparticles have another hurdle to overcome - escaping the bloodstream

Many medically minded researchers are in hot pursuit of designs that will allow drug-carrying nanoparticles to navigate tissues and the interiors of cells, but University of Michigan engineers have discovered that these particles have another hurdle to overcome: escaping the bloodstream.

7 Feb 2013

New analysis casts doubt on American Heart Association omega-6 PUFA advice

Dietary advice about fats and the risk of heart disease is called into question on bmj.com as a study shows that replacing saturated animal fats with polyunsaturated vegetable fats is linked to an increased risk of death among patients with heart disease.

7 Feb 2013

UT Dallas research to determine link between hearing deficits and likelihood of falls

UT Dallas researchers are recruiting patients for a new study aimed at determining a connection between hearing deficits and the likelihood of falls.

7 Feb 2013

Occupational exposure to magnetic fields may moderately increase risk of Alzheimer's, ALS

Occupational exposure to magnetic fields (MF) may be associated with "moderately increased risk" of certain neurodegenerative diseases—including Alzheimer's and amyotrophic lateral sclerosis, reports the February Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).

7 Feb 2013

Misonix revenue increases 19% to $8.0M for six months ended December 31, 2012

Misonix, Inc., a surgical device company that designs, manufactures and markets innovative therapeutic ultrasonic products worldwide for spine surgery, cranial maxillo – facial surgery, neurosurgery, wound debridement, cosmetic surgery, laparoscopic surgery and other surgical applications, today reported financial results for the six-months and the second quarter of fiscal year 2013, ended December 31, 2012.

7 Feb 2013

Researchers design guideline for physicians and patients on Androgen Insensitivity Syndrome

University of Granada researchers have designed a guideline for physicians and patients on the Androgen Insensitivity Syndrome (AIS), a rare disease that makes the subject develop reverse sex, which occurs when a subject looks like a woman but has male genes.

7 Feb 2013

Basis of antidepressant drugs and electroconvulsive therapy found

Through a series of investigations in mice and humans, Johns Hopkins researchers have identified a protein that appears to be the target of both antidepressant drugs and electroconvulsive therapy. Results of their experiments explain how these therapies likely work to relieve depression by stimulating stem cells in the brain to grow and mature.

7 Feb 2013

Liver gene found to regulate cholesterol and fat blood levels

Researchers have identified a microRNA liver gene, miR-27b, which regulates lipid (cholesterol or fat) levels in the blood. This regulator gene controls multiple genes involved in dyslipidemia—abnormal blood cholesterol levels that can contribute to heart disease.

7 Feb 2013

Four-step process delivers specific, reliable clinical rules

Dutch researchers have developed a four-step strategy for formulating clinical decision support systems, which they say could help reduce “alert fatigue.”

7 Feb 2013

Anxiety may contribute to cognitive dysfunction in bipolar disorder

Compromised cognitive and adaptive functioning in euthymic patients with bipolar disorder may be partly explained by related comorbid anxiety, suggest researchers.

7 Feb 2013

Diabetic peripheral neuropathy risk highlighted in children

US researchers call for clinical guidelines for detection of diabetic peripheral neuropathy in children after finding that a significant proportion of young patients are affected.

7 Feb 2013

Antibiotics help severely malnourished children recover

Giving severely malnourished children antibiotics in addition to nutritional therapy significantly improves their chances of making a full recovery compared with nutritional therapy alone, say researchers.

7 Feb 2013

Eletrocardiographic mapping nearing clinical utility

Electocardiographic mapping may offer a noninvasive and accurate alternative to a standard electrophysiologic study, say researchers.

7 Feb 2013

Combination RT offers hope to late-stage esophageal cancer patients

Just over half of patients with advanced-stage esophageal cancer who are unsuitable for standard curative treatment survive for a year after receiving a combination of external beam radiotherapy and high-dose rate brachytherapy, report researchers.

7 Feb 2013

Telephone physiotherapy reduces treatment delays

Providing an initial physiotherapy assessment by telephone for patients with neuromusculoskeletal problems may help reduce waiting times, say UK researchers.

7 Feb 2013

Chlorhexidine bathing protects vulnerable hospital patients

Bathing hospital patients with chlorhexidine-impregnated washcloths reduces the risk for them acquiring multidrug-resistant organisms and developing bloodsteam infections, show study findings.

7 Feb 2013

Glimmer of hope for imatinib-resistant GIST

The monoclonal antibody SR1 can significantly inhibit gastrointestinal stromal tumor cell growth, report researchers in the Proceedings of the National Academy of Sciences.

7 Feb 2013

First new TB vaccine in century fails initial testing

The first of a series of new vaccines that have been developed to combat tuberculosis failed to show efficacy compared with placebo in South African infants, show results from a phase II trial.

7 Feb 2013