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NCI-funded study to identify metabolic vulnerabilities of particularly aggressive cancers

Eileen White, PhD, associate director for basic science at The Cancer Institute of New Jersey and professor of molecular biology and biochemistry at Rutgers, The State University of New Jersey, and colleagues from Princeton University have been awarded a new five-year, $2.4 million dollar research grant from the National Cancer Institute.

7 Dec 2012

Medicare changes central as 'fiscal cliff' countdown continues

The Washington Post reports that some Republicans are urging House leaders to back higher tax rates for the wealthy in exchange for a deal to rein in spending on safety-net programs. Other news outlets report that AARP and other groups are warning lawmakers about the hazards of cutting benefits as part of a deficit reduction package.

7 Dec 2012

Study demonstrates how parasites enter the brain to influence its host

Toxoplasma is a common 'cat parasite', and has previously been in the spotlight owing to its observed effect on risk-taking and other human behaviours. To some extent, it has also been associated with mental illness. A study led by researchers from Karolinska Institutet in Sweden now demonstrates for the first time how the parasite enters the brain to influence its host.

7 Dec 2012

Blog series examines challenges, solutions in global AIDS response

The Skoll World Forum and the Bill & Melinda Gates Foundation's "Impatient Optimists" blog have co-produced a blog series highlighting key challenges in the global response moving forward and examining how the international community can overcome these challenges.

7 Dec 2012

Scientists describe network map of genes involved in pain perception

Scientists in Australia and Austria have described a "network map" of genes involved in pain perception, with remarkable similarity from fruit flies to people. The work should help identify new analgesic drugs.

7 Dec 2012

Al Jazeera examines HIV/AIDS in Persian Gulf

Al Jazeera examines HIV/AIDS in the Persian Gulf, writing, "For much of the past two decades, there has been an information vacuum in the Gulf for epidemiological data on HIV and AIDS.

7 Dec 2012

Genomic sequencing reveals therapeutic drug targets for metastatic triple-negative breast cancer

Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Research Institute (TGen) and US Oncology Research.

7 Dec 2012

U.S. must maintain leadership in AIDS fight, bipartisan support of PEPFAR

Through travel to Africa and "as chairman and ranking member of the Senate Foreign Relations Subcommittee on African Affairs, we've seen firsthand the enormous toll of HIV/AIDS on families, communities and economies," Sen. Chris Coons (D-Del.) and Sen. Johnny Isakson (R-Ga.) write in the Huffington Post's "Politics" blog.

7 Dec 2012

Study finds previously unrecognized way that degradation can occur in silicone-urethane plastics

Scientists have discovered a previously unrecognized way that degradation can occur in silicone-urethane plastics that are often considered for use in medical devices. Their study, published in ACS' journal Macromolecules, could have implications for device manufacturers considering use of these plastics in the design of some implantable devices, including cardiac defibrillation leads.

7 Dec 2012

Polls show public reluctance for trimming Medicare to curb the deficit

A new AP-GfK poll found most American favor letting tax cuts expire for top wage earners and a Quinnipiac poll found that voters oppose cutting Medicaid spending and increasing the Medicare eligibility age.

7 Dec 2012

Study identifies epigenetic events critical to cancer cell survival

USC Norris Comprehensive Cancer Center research that identifies specific genes that have to be turned off in order for cancer cells to survive was named one of the top major advances in cancer research this year by the American Society of Clinical Oncology (ASCO).

7 Dec 2012

Global Fund names interim inspector general

"Norbert Hauser has been named interim inspector general of the Global Fund to Fight AIDS, Tuberculosis and Malaria," Devex's "Development Newswire" reports, adding, "The recently retired lawyer and international auditor will serve in this temporary appointment for up to nine months while the Global Fund searches for a permanent inspector general to replace John Parsons," whose employment was terminated last month.

7 Dec 2012

Boston Scientific’s Precision Spectra Spinal Cord Stimulator System receives CE Mark approval

Boston Scientific Corporation has received CE Mark approval and has begun the European market launch of the Precision Spectra Spinal Cord Stimulator (SCS) System.

7 Dec 2012

States trying managed care for 'dual eligibles' - Medicare/Medicaid recipients

People who qualify for Medicare and Medicaid - many of whom are elderly and in nursing homes - need lots of often-expensive care.

7 Dec 2012

Kidney cancer survival rates: an interview with Dr Wong-Ho Chow

There are two major forms of kidney cancer. One is called renal cell cancer, which is an adenocarcinoma that occurs in the renal parenchyma. The other major type is called renal pelvis cancer, which is mostly of transitional cell type and they form in the centre of the kidney where the urine collects.

7 Dec 2012

Disturbances in several immune-system-related pathways contribute to development of ASDs

Researchers using novel approaches and methodologies of identifying genes that contribute to the development of autism have found evidence that disturbances in several immune-system-related pathways contribute to development of autism spectrum disorders.

7 Dec 2012

Study finds longer course of tamoxifen treatment cuts breast cancer deaths

The finding that women should be taking the drug for twice as long as is now customary came out of study of nearly 7,000 women from 36 countries.

7 Dec 2012

New genetic process could provide novel target for treatment of neurodevelopmental disorders

Researchers at the Douglas Mental Health University Institute, have discovered a new genetic process that could one day provide a novel target for the treatment of neurodevelopmental disorders, such as intellectual disability and autism.

7 Dec 2012

U.S. government announces grants for implementation science projects on PMTCT

Last week, the U.S. government announced up to $7.5 million in grants over the next two years to fund "implementation science projects exploring how to achieve the goal of eliminating new pediatric HIV infections while keeping mothers alive," the Center for Global Health Policy's "Science Speaks" blog reports.

7 Dec 2012

JAACAP editorial addresses 'translation gap' in autism research

An editorial published in the November 2012 issue of the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP) discusses the challenge of translating scientific research in autism into clinical practice, and presents a series of studies published over several months that address this 'translation gap'.

7 Dec 2012