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Ponatinib offers new hope in drug-resistant leukemia

An investigational tyrosine kinase inhibitor, ponatinib, has shown high levels of activity in patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.

5 Dec 2012

BMI influences hormone levels in overweight, obesity

A high body mass index has no significant impact on parameters of sperm quality, although it does lower serum levels of testosterone, luteinizing hormone, and prolactin, say researchers.

5 Dec 2012

Bipolar disorder prevalent in panic disorder patients

Bipolar disorder is common among Japanese patients with panic disorder, research shows.

5 Dec 2012

Depression, anxiety not linked to psychosis transition

Depression and anxiety disorders are common in patients at increased clinical risk for psychosis, but do not appear to influence transition to full-blown psychosis, say UK researchers.

5 Dec 2012

Age, breed, punishment type, training affect dogs' aggression

Dogs' aggression toward other dogs in the household is associated with increasing age, use of positive punishment/negative reinforcement techniques, and attending ring-craft classes, report UK researchers.

5 Dec 2012

Nerve stimulation improves hand use in spinal cord injury patients

A method combining transcranial magnetic stimulation with electrical stimulation of peripheral nerves in the wrist temporarily improves hand use in spinal cord injury patients, show research findings published in Current Biology.

5 Dec 2012

NICE reject intravitreal implant for diabetic macular edema

The UK National Institute for Health and Clinical Excellence has not recommended a fluocinolone acetonide intravitreal implant for individuals with diabetic macular edema who do not respond to existing therapies.

5 Dec 2012

Vitamin D and women’s risk for multiple sclerosis

Women who have high vitamin D levels are at a decreased risk for developing multiple sclerosis, shows research.

5 Dec 2012

‘Old’ erythrocytes little problem in noncardiac surgery

Erythrocytes that have been stored for several weeks before use may not cause problems in patients who receive transfusions during noncardiac surgery, a large retrospective analysis suggests.

5 Dec 2012

‘Pain as reward’ raises tolerance threshold

An individual’s ability to tolerate pain is influenced by their preconceptions and beliefs about the meaning of the pain, Italian researchers have shown.

5 Dec 2012

RXi commences RXI-109 Phase 1 study for management of surgical scars and keloids

RXi Pharmaceuticals Corporation, today announced that dosing with their anti-scarring drug, RXI-109, for the management of surgical and hypertrophic scars and keloids has been initiated.

5 Dec 2012

Surprising discovery about physical properties of cancer cells

A surprising discovery about the physical properties of cancer cells could help improve a new diagnostic approach - a liquid biopsy - that detects, measures, and evaluates cancer cells in blood.

5 Dec 2012

University of Chicago professor wins Manpei Suzuki International Prize for diabetes work

Graeme Ian Bell, PhD, the Louis Block Distinguished Service Professor of Medicine and Human Genetics and an investigator in the Kovler Diabetes Center at the University of Chicago, has been awarded the Manpei Suzuki International Prize for 2012 for his pioneering work in understanding the role of genetics in the diagnosis and treatment of diabetes.

5 Dec 2012

Study provides important data about fertility window of women with childhood cancer

This study provided important data about the fertility window of women who had suffered from childhood cancer and information concerning the associated risk factors, but did not confirm the greater risk of premature menopause (before the age of 40) that was reported by the American studies.

5 Dec 2012

New metabolic biomarkers can detect risk of illnesses in advance

One of the big challenges of biomedicine is understanding the origin of illnesses in order to improve early detection and significantly increase recovery rates, as well as being able to do what CNIO researchers call preventive molecular medicine, which consists of identifying those individuals who have a greater molecular risk of suffering certain pathologies in order to prevent them.

5 Dec 2012

Children with HIV more likely to develop atherosclerosis

Children with HIV have a 2.5 fold increased risk of atherosclerosis, according to research presented at EUROECHO and other Imaging Modalities 2012. Antiretroviral treatment, lipid lowering drugs and prevention with healthy lifestyles are needed to prevent early death from cardiovascular disease.

5 Dec 2012

Copper can prevent horizontal transmission of genes in antibiotic-resistant bacteria

New research from the University of Southampton has shown that copper can prevent horizontal transmission of genes, which has contributed to the increasing number of antibiotic-resistant infections worldwide.

5 Dec 2012

Smoking cessation support: an interview with Robyn Whittaker

Tobacco smoking involves a physiological addiction to nicotine for a lot of people. Quitting can cause some nasty symptoms due to the withdrawal of nicotine.

5 Dec 2012

Parental involvement prevents or limits alcohol and marijuana use by children

New research from North Carolina State University, Brigham Young University and the Pennsylvania State University finds that parental involvement is more important than the school environment when it comes to preventing or limiting alcohol and marijuana use by children.

5 Dec 2012

New method can generate stable human mesenchymal stem cells for bone engineering

Human mesenchymal stem cells (hMSCs) can develop into bone cells and are useful for tissue engineering and regeneration. However, when grown in the laboratory they quickly lose their ability to continue dividing and they die.

5 Dec 2012