Air pollution exposure associated with cardiovascular events among US hemodialysis patients

In a study published in the American Journal of Kidney Diseases (AJKD), researchers found that US adults receiving hemodialysis with higher levels of air pollution exposure have more heart attacks and strokes compared to those with low levels of exposure; strongest associations of air pollution exposure with cardiovascular events were noted among patients who were Asian, older, or had chronic lung disease at dialysis initiation.

Long-term exposure to air pollution, also called PM2.5, has been linked to adverse cardiovascular (CV) outcomes. However, little is known about the association of PM2.5 and outcomes among patients receiving dialysis, individuals with high CV disease burdens. Led by Yuzhi Xi, researchers conducted an epidemiological study to assess the association between the annual PM2.5 exposure and CV events and death among patients receiving regular outpatient hemodialysis in the United States between 2011-2016.

They found a higher risk of heart attacks, strokes, and related events in patients exposed to higher levels of air pollution. Stronger associations between air pollution and adverse health events were observed among patients who were older at the start of dialysis, had chronic obstructive pulmonary disease, or were Asian. These findings bolster the evidence base linking air pollution and adverse health outcomes and may inform policy makers and clinicians. Exposure mitigation on the individual-level could be beneficial to at-risk individuals. Future studies should be conducted to study additional air pollutants' (Ozone, NOx, etc.) potential health impact among such vulnerable populations.

Journal reference:

Xi, Y., et al. (2022) Association Between Long-term Ambient PM2.5 Exposure and Cardiovascular Outcomes Among US Hemodialysis Patients. American Journal of Kidney Diseases.


The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.

You might also like...
Groundbreaking method developed for analyzing heart MRI scans with AI