1. This article is not well written
    Bambie Bambie Bambie Bambie Australia says:
    July 28, 2015 at 10:34 PM

    The article is not well written and has some misinformation in it, But basically it should be stating the following.

    1. The mutation in the DISC1 gene prevents the proper formation of the DISC1 protein.

    2. In order for the brain to grow properly, the DISC1 protein needs to bind with one other protein called NUDEL and an enzyme called LIS.

    3. By preventing DISC1 in mice from binding to NUDEL and LIS, using a chemical called Tamoxifen the brain can't grow properly.

    4. That's it.

    If the mutated DISC1 gene can't bind to NUDEL or LIS then how can our brains grow? They do grow though.

    So in order to help the scientists get more funding, which is all they really want, and a Nobel prize, I will part with some of my immense knowledge on the subject.

    The NUDEL protein and the LIS enzyme are probably needed for increasing the speed of synapse production. Not for the actual production itself. This is my educated guess on the matter.

    Reply
The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
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