1. Too many errors in the opening phrase!
    Dhinakar Kompala Dhinakar Kompala United States says:
    May 29, 2025 at 9:29 AM

    The opening phrase in the Background section "Monellin and brazzein, artificial small-molecule sweeteners, have been widely used ..." has too many errors:  These two are natural proteins and they are (1) NOT artificial, (2) NOT small-molecules, and (3) NOT widely used yet.  So read the rest of this article with a pinch of salt...

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