Kuano Ltd.

Kuano's approach is to combine state-of-the-art simulation and AI to add quantum detail to structure based drug discovery. Our unique fusion of drug hunting and technology expertise allows us to illuminate new areas of chemical space enabling the design of next generation medicines.

Enzyme reactions are governed by complex quantum mechanical laws. Classical drug design ignores this and cannot make use of tight binding states which occur during these reactions. Kuano has developed a Quantum Lens to capture these “Transition States” and use them as templates for effective, low toxicity, drugs.

Kuano's detailed Quantum simulations reveal differences between enzymes that allow us to target each one individually, without affecting other, healthy, enzymes. The subtle details revealed by the Quantum Lens provide unique profiles that we use to uncover non-intuitive drug molecules that cannot be found with other methods.

The Kuano platform uses the key chemical features of a Transition State to define a filter for matching stable molecules (the Quantum Pharmacophore). Combining this template with Kuano’s suite of AI tools, our skilled drug hunters are able to to find the right drug candidates faster.