Surface enhanced Raman scattering (SERS) is an analytical technique with several advantages over competitive techniques in terms of improved sensitivity and multiplexing. We have made great progress in the development of SERS as a quantitative analytical method, in particular for the detection of DNA. However, the lack of quantitative data relating to real examples has prevented more widespread adoption of the technique.
At Pittcon 2018, Karen Faulds demonstrated the development functionalised nanoparticles as sensing materials for the detection of bacteria and proteins at ultra low levels. They achieved this by combining functionalised silver or gold nanoparticles with SERS. This combination can result in extremely sensitive and selective biosensing with unprecedented multiplexing capabilities.
Watch the full presentation below:
Karen Faulds - Multiplexed and Sensitive Bioanalysis Using SERS from AZoNetwork on Vimeo.