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This webinar will explore advances in the diagnosis of Cushing’s syndrome and adrenal insufficiency, two endocrine disorders with significant clinical and operational challenges.
For Cushing’s syndrome, where no single gold-standard test exists, the session will review current screening approaches - including the Overnight Dexamethasone Suppression Test, Urinary Free Cortisol, and Late-Night Salivary Cortisol - and examine the emerging role of salivary cortisone in improving diagnostic accuracy.
For adrenal insufficiency, a life-threatening condition with rising prevalence, the webinar will highlight limitations of standard testing, such as the ACTH (Short Synacthen) test, and present evidence supporting home-based waking salivary cortisone as a simple, non-invasive screening alternative with the potential to reduce diagnostic delays and resource burden.
The session will also address key considerations for integrating new diagnostic methods into routine clinical practice.
Join the free webinar with certification of attendance now.
Join the Webinar to Learn:
- How salivary cortisone testing using LC-MS/MS improves the accuracy and reliability of adrenal disease assessment
- The role of LC-MS/MS in screening for Cushing syndrome, including advantages over traditional cortisol testing
- The role of LC-MS/MS in screening for adrenal insufficiency
- Best practices for implementing high-sensitivity endocrineity endocrine assays on the Waters™ Xevo™ TQ-XS Mass Spectrometer for routine clinical use
Xevo™ is a trademark of Waters Corporation or its affiliates
This Webinar is Ideal For:
- Clinical laboratory directors and managers
- Clinical chemists and endocrinologists
- LC-MS/MS scientists and assay developers
- Hospital laboratory professionals
- Independent clinical laboratories (ICLs)
- Researchers focused on endocrine disorders and adrenal disease
- Healthcare professionals involved in diagnosing and managing Cushing syndrome
About the Webinar Speaker
Brian Keevil is a Consultant Clinical Scientist at Manchester University NHS Foundation Trust. He is Clinical Lead for the Clinical Biochemistry Department at Wythenshawe hospital and director of the clinical mass spectrometry unit.
His research interests involve the development and introduction of novel mass spectrometry methods for the measurement of therapeutic drugs and steroids. His laboratory has pioneered the use of these techniques many of which are used to underpin routine clinical services and collaborative international research projects.
Steroids have been a particular interest, and the laboratory performs a wide range of steroid assays in blood urine and saliva samples. These methods are being used to refine existing endocrine protocols and to explore the use of newer novel steroids such as the 11 oxygenated steroids in the diagnosis and management of endocrine conditions. He is the recipient of a UKRI scholars grant to investigate the use of salivary cortisone in the investigation of adrenal disease.
He has published more than 240 peer reviewed publications and is an honorary Professor at the University of Manchester.