Advancing biopharmaceutical manufacturing with a new CHO cell isolation platform

The University of Manchester's Centre of Excellence in Biopharmaceuticals (COEBP) has developed a biopharmaceutical manufacturing platform that allows rapid isolation of high-producing CHO cell populations.

The researchers needed to evaluate the antibody titer in hundreds of study samples. Due to the substantial manual processing necessary for ELISA, cell cultures were frozen to regulate throughput. Data was obtained retrospectively, delaying decisions and resulting in lengthy, unproductive periods.

The lab introduced antibody titer measurement using the Amperia™ system, streamlining measurement from crude samples and enabling same-day results.

Freezing and thawing cell cultures can delay reintroduction into productive workflows. Reducing the need for sample freezing helped limit extended periods of unproductive time.

Key takeaways

Amperia™ reduces the need to batch and store samples prior to analysis, helping avoid delays of up to three weeks.

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About Abselion

Abselion started in 2018, at that time under the name HexagonFab, in a small corner of a laboratory at the University of Cambridge.

We set out with the humble goal to make protein research simpler. Scientists should be able to pursue their passion for discovery and innovation, rather than spend their valuable time with tedious, manual tasks. With RED we had access to the ideal technology to create this product. A product that is so compact that it could fit on every bench, and so affordable that it is accessible to everyone. Over the years we have designed, built and tested our first product Amperia and we’re proud to introduce it to the world.​

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