Carcinomas News and Research

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Study: Mammary basal cell lineage contributes to breast cancer heterogeneity

A key hurdle in treating breast cancers is intratumoral heterogeneity, or the presence of multiple different cell populations within the same tumor that have distinct characteristics such as gene expression, metabolism and ability to divide, spread and grow.

29 Oct 2020

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Neoadjuvant, or pre-surgical, combination treatment with the immune checkpoint inhibitors tremelimumab (anti-CTLA-4) and durvalumab (anti-PD-1) was well-tolerated and showed early signs of activity in certain patients with localized bladder cancer who do not have standard treatment options available, according to a Phase I clinical trial conducted by The University of Texas MD Anderson Cancer Center.

13 Oct 2020

Chemists suggest a new domino reaction to produce organic compounds against cancers

A team of chemists from RUDN University suggested a new reaction to produce organic compounds in one vessel.

9 Oct 2020

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival.

21 Sep 2020

First clinical trial could become an effective way to deliver chemotherapy to abdominal cancer patients

City of Hope surgical researchers are the first in the nation to open a clinical trial that could one day become an effective way to deliver chemotherapy to abdominal cancer patients who currently have very few treatment options.

11 Aug 2020

Investigational drug shows promising results for treating HNSCC tumors

Head and neck cancer is one of the leading causes of cancer-related deaths worldwide, and squamous cell carcinomas (HNSCC) account for the majority of these cases.

31 Jul 2020

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that IQGAP1 is a signaling scaffold implicated in TNBC, but its mechanism is unknown.

30 Jun 2020

Rice lab's fluorescent tag project reveals new method to kill tumors

A Rice University lab's project to make better fluorescent tags has turned into a method to kill tumors. Switching one atom in the tag does the trick.

11 Jun 2020

Researchers evaluate survivin expression in neuroendocrine tumors

Volume 11, Issue 23 of @Oncotarget reported that tissue microarrays of 132 patients were stained for survivin using immunohistochemistry and correlated with outcomes.

10 Jun 2020

New technique offers high-resolution 3D view inside tumors

Malignant tumors consume nutrients and oxygen faster than healthy cells. To do so, they recruit blood vessels in their environment. Depending on tumor type and genetic profile, there are differences on how tumors look internally.

26 May 2020

Scientists discover how an obscure protein promotes breast cancer progression

South Australian scientists have made a critical breakthrough, discovering how an obscure protein causes breast cancer to develop and grow more quickly.

25 May 2020

Exposure to fine particulate matter can increase mortality in young patients with certain cancers

An analysis of nearly 16,000 young patients with cancer in Utah revealed that exposure to fine particulate matter was associated with increased mortality at five and 10 years after diagnosis of certain cancers.

13 May 2020

Researchers report decline in cancer diagnoses due to COVID-19 crisis

Cancer care has dramatically changed as a result of the measures taken during the COVID-19 pandemic: many patients have not been going to their GPs, or putting it off, and have been referred to the hospital later.

11 May 2020

Patients with aggressive form of skin cancer can benefit from new type of immunotherapy

In what is believed to be a first-of-its-kind study to evaluate the safety of a type of immunotherapy before surgery in patients with an aggressive form of skin cancer, researchers report that the treatment eliminated pathologic evidence of cancer in nearly half of the study participants undergoing surgery.

27 Apr 2020

Carcinomas News and Research

Study: Mammary basal cell lineage contributes to breast cancer heterogeneity

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Chemists suggest a new domino reaction to produce organic compounds against cancers

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

First clinical trial could become an effective way to deliver chemotherapy to abdominal cancer patients

Investigational drug shows promising results for treating HNSCC tumors

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

Rice lab's fluorescent tag project reveals new method to kill tumors

Researchers evaluate survivin expression in neuroendocrine tumors

New technique offers high-resolution 3D view inside tumors

Scientists discover how an obscure protein promotes breast cancer progression

Exposure to fine particulate matter can increase mortality in young patients with certain cancers

Researchers report decline in cancer diagnoses due to COVID-19 crisis

Patients with aggressive form of skin cancer can benefit from new type of immunotherapy

Overexpression of hPCL3S could contribute to tumor progression in prostate cancer

UArizona receives $6.9 million grant to make advances in skin cancer prevention and treatment

RNA affecting skin cancer progression discovered

Study looks into the virome of early stage, p16-positive OPSCC and neck metastasis

Scientists discover new drug target for prostate cancer in the non-coding genome

Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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