Chronic Pain News and Research

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Lupus Research Alliance awards early career scientists for innovative research

Today, the Lupus Research Alliance (LRA), the world's largest private funder of lupus research, announced the recipients of the 2025 Empowering Lupus Research (ELR) Career Development Award and Postdoctoral Award.

5 Aug 2025

New analgesic shows promise as opioid alternative

Opioids like morphine are widely used in medical practice due to their powerful pain-relieving effects. However, they carry the risk of serious adverse effects such as respiratory depression and drug dependence.

4 Aug 2025

Dual tobacco use: Examining patterns in Hispanic and non-Hispanic Black men with chronic illness

Cannabis use is gaining popularity in the United States, driven by growing legalization, public acceptance and diverse methods of consumption.

4 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

UCSF research maps over 600 conditions linked to endometriosis

Records from millions of patients at UC health centers found correlations between endometriosis, one of the most common diseases in women, and a bounty of other diseases.

31 Jul 2025

Study reveals how old wounds increase sensitivity to stress

A wound can leave a lasting imprint - even after it has healed. A new study in Current Biology finds that past injuries can quietly prime the body to overreact and be more sensitive to stress, pain and fear long after the damage is gone.

28 Jul 2025

Research uncovers ME/CFS's systemic impact for targeted therapies

Millions suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition often overlooked due to the lack of diagnostic tools, may be closer to personalized care, according to new research that shows how the disease disrupts interactions between the microbiome, immune system, and metabolism.

26 Jul 2025

Study finds continued use of risky antiseizure drugs during pregnancy

Despite evidence of the risk of malformations at birth, or birth defects, use of some antiseizure drugs during pregnancy has persisted, according to a study published on July 23, 2025, in Neurology, the medical journal of the American Academy of Neurology.

24 Jul 2025

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

Elenagen™, a novel DNA plasmid therapy that previously demonstrated high clinical benefit and low toxicity in cancer patients, has now shown significant promise in alleviating chronic pain demonstrating a 90% success rate.

23 Jul 2025

New collaborative effort harnesses AI to drive ALS drug discovery in Louisiana

Answer ALS is proud to announce the launch of a groundbreaking collaborative initiative aimed at accelerating AI-powered drug discovery for ALS and other neurodegenerative diseases.

23 Jul 2025

Overuse injuries spark lasting pain and mood changes through inflammation, rat study finds

Repetitive reaching tasks in mature female rats triggered persistent pain-like and sickness behaviors linked to a surge in IL-6-driven inflammation throughout muscles, blood, and the brain. These findings reveal how overuse injuries provoke both physical and mood-related symptoms through a neuroimmune cascade.

20 Jul 2025

Sound stress alone induces pain sensitivity and brain inflammation

Pain is an important physiological response in living organisms. While physical pain is an outcome of tissue damage, pain can manifest as diverse unpleasant sensory and emotional experiences. Many studies report that emotional or psychological stress enhances pain responses.

18 Jul 2025

3D-printed implant offers a potential new route to repair spinal cord injuries

A research team at RCSI University of Medicine and Health Sciences has developed a 3-D printed implant to deliver electrical stimulation to injured areas of the spinal cord, offering a potential new route to repair nerve damage.

15 Jul 2025

Research explores the link between lower micronutrient levels and chronic pain

Lower levels of certain vitamins and minerals were found to be associated with chronic pain in a recently completed study led by researchers at the University of Arizona Health Sciences and published in Pain Practice.

15 Jul 2025

Social media analysis reveals emotional burden of children with multiple health conditions

Children with multiple long-term health issues undergo severe emotional stress at the same time as they are trying to cope with the physical challenges of their condition, a study has found.

12 Jul 2025

Frequent gabapentin use linked to higher dementia and cognitive impairment risk

Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)--29% and 85%, respectively-finds a large medical records study published online in the journal Regional Anesthesia & Pain Medicine.

10 Jul 2025

Scientists discover pathway linking physical pain to emotional suffering

Pain isn't just a physical sensation-it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering.

10 Jul 2025

Adding anxiety to Pennsylvania's medical cannabis program changes patient demographics

Within months of Pennsylvania's medical cannabis program adding anxiety as a qualifying condition, that diagnosis quickly rose to become the most common for cannabis certifications, according to a study by researchers at the University of Pittsburgh and Johns Hopkins University. The study was published today in Annals of Internal Medicine.

8 Jul 2025

Study finds nearly double risk of depression and anxiety in autoimmune patients

Living with an autoimmune disease is linked to a near doubling in the risk of persistent mental health issues, such as depression, generalised anxiety, and bipolar disorder, with these risks higher in women than in men, finds a large population-based UK study, published in the open access journal BMJ Mental Health.

25 Jun 2025

Flexible wireless implant offers hope for chronic pain sufferers

Chronic pain is a debilitating condition that severely impacts quality of life, often leading to reliance on opioid medications with their severe side effects and addiction risks.

24 Jun 2025