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Scientists resolve 3D protein structures to combat dangerous infectious diseases

An international team of scientists including the Computation Institute has determined the 3-D atomic structures of more than 1,000 proteins that are potential targets for drugs and vaccines to combat some of the world's most dangerous emerging and re-emerging infectious diseases.

22 Jun 2017

Researchers identify key Lassa virus structure using powerful Argonne X-rays

Before Ebola virus ever struck West Africa, locals were already on the lookout for a deadly pathogen: Lassa virus.

13 Jun 2017

TSRI study reveals first-ever structure of Lassa virus protein

Before Ebola virus ever struck West Africa, locals were already on the lookout for a deadly pathogen: Lassa virus. With thousands dying from Lassa every year - and the potential for the virus to cause even larger outbreaks- researchers are committed to designing a vaccine to stop it.

1 Jun 2017

Scripps scientists make important advance in HIV vaccine design

Scientists at The Scripps Research Institute (TSRI) have made another important advance in HIV vaccine design. The development was possible thanks to previous studies at TSRI showing the structures of a protein on HIV’s surface, called the envelope glycoprotein. The scientists used these structures to design a mimic of the viral protein from a different HIV subtype, subtype C, which is responsible for the majority of infections worldwide.

29 May 2017

High quality microplate readers built to last decades by German manufacturer BMG Labtech

From the outset BMG LABTECH’s mission was to develop microplate readers guaranteed to provide optimum performance for years. BMG LABTECH has continued this philosophy while continuing to remain at the forefront of microplate reading, always introducing innovative and unique technologies. All microplate readers are built to be extremely reliable and robust over decades, some of BMG LABTECH’s very first products are still in use across the globe.

25 May 2017

Unique microscope reveals clues to destructive autoimmune disease

Using a unique microscope capable of illuminating living cell structures in great detail, researchers at the University of Colorado Anschutz Medical Campus have found clues into how a destructive autoimmune disease works, setting the stage for more discoveries in the future.

26 Apr 2017

Using nanodiamonds to see smaller

Many of the most fundamental, life governing biological processes take place at size and time scales that remain invisible with current imaging technologies. Understanding how the molecules that underlie these processes move, interact and change could pave the way for new treatments, cures and the development of novel drug therapies.

7 Apr 2017

Research project aims to develop new chip-sized optical microscope with high resolution capabilities

Creating a new type of chip-sized optical microscope with high resolution capabilities is the challenge of ChipScope, a European project led by the University of Barcelona which counts with the participation of SMEs, universities and research institutes from five European countries.

6 Apr 2017

ISS crew members grow crystals for drug development

Crew members aboard the International Space Station will begin conducting research this week to improve the way we grow crystals on Earth. The information gained from the experiments could speed up the process for drug development, benefiting humans around the world.

31 Mar 2017

Phase-contrast X-ray imaging could identify tumors earlier

Phase-contrast X-ray imaging differs from conventional X-rays because it uses a different physical principle.

29 Mar 2017

Chinese researchers apply new modeling method to improve acoustic simulations in HIFU therapy

High-intensity focused ultrasound is a breakthrough therapeutic technique used to treat tumors. The principle of this noninvasive, targeted treatment is much like that of focusing sunlight through a lens, using an ultrasonic transducer like a convex lens to concentrate ultrasound into a small focal region.

28 Mar 2017

Bacterial cell counting and sizing using the Multisizer

In this interview, Dr. Rich Jones introduces bacterial cell counting and an example of when the Multisizer 4e from Beckman Coulter has been used for this application.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 15 Mar 2017

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery.

3 Mar 2017

Spatial structure of amyloid fibrils linked to Parkinson's disease highly dependent on salt concentration

By combining two-dimensional infrared spectroscopy and atomic force microscopy, Amsterdam researchers have established that the spatial structure of amyloid fibrils related to Parkinson's disease is highly dependent on salt concentration during protein aggregation.

6 Feb 2017

Review highlights how light-sensing bacterial protein's structure aids biomedical research

A light-sensing protein from a salt-loving, sulfur-forming microbe has proved key to developing methods essential to advanced drug discovery, understanding human vision and other biomedical applications.

1 Feb 2017

Researchers develop new ‘needle-pulse' beam pattern that could have wide range of applications

A new beam pattern devised by University of Rochester researchers could bring unprecedented sharpness to ultrasound and radar images, burn precise holes in manufactured materials at a nano scale -- even etch new properties onto their surfaces.

28 Jan 2017

Super-resolution fluorescence microscopy sheds light on brain’s molecular mechanism

Advances in microscopy techniques have often triggered important discoveries in the field of neuroscience, enabling vital insights in understanding the brain and promising new treatments for neurodegenerative diseases such as Alzheimer's and Parkinson's.

29 Dec 2016

Diffraction News and Research

Scientists resolve 3D protein structures to combat dangerous infectious diseases

Researchers identify key Lassa virus structure using powerful Argonne X-rays

TSRI study reveals first-ever structure of Lassa virus protein

Scripps scientists make important advance in HIV vaccine design

High quality microplate readers built to last decades by German manufacturer BMG Labtech

Unique microscope reveals clues to destructive autoimmune disease

Using nanodiamonds to see smaller

Research project aims to develop new chip-sized optical microscope with high resolution capabilities

ISS crew members grow crystals for drug development

Phase-contrast X-ray imaging could identify tumors earlier

Chinese researchers apply new modeling method to improve acoustic simulations in HIFU therapy

Bacterial cell counting and sizing using the Multisizer

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

Spatial structure of amyloid fibrils linked to Parkinson's disease highly dependent on salt concentration

Review highlights how light-sensing bacterial protein's structure aids biomedical research

Researchers develop new ‘needle-pulse' beam pattern that could have wide range of applications

Super-resolution fluorescence microscopy sheds light on brain’s molecular mechanism

Selecting the correct microscope camera in digital pathology

Tiny, glowing crystals could be powerful new tool to detect and clean contaminated water sources

Study shows power of haptic interfaces, web computing to create shareable scientific environment in crystallography

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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