Endoplasmic reticulum (ER) News and Research

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U-M researchers envision new ways to avoid inappropriate ER use for mild eye problems

Pinkeye isn't a medical emergency. Neither is a puffy eyelid. But a new study finds that nearly one in four people who seek emergency care for eye problems have those mild conditions, and recommends ways to help those patients get the right level of care.

15 Feb 2017

Researchers explore role played by nicotine in grouping of nicotinic receptors within the brain

Nicotine -- the primary compound found within tobacco smoke -- is known to change the grouping of some subtypes of nicotinic receptors, but the mechanisms for nicotine addiction remain unclear.

15 Feb 2017

Researchers find drugs that could replicate effects of gastric bypass surgery

Gastric bypass surgery is one of the most successful treatments for obesity and related disorders; however, some patients may not want to undergo surgery.

8 Feb 2017

PERK protein could be target for development of new drugs for progressive supranuclear palsy

The brain disease "progressive supranuclear palsy" (PSP) is currently incurable and its symptoms can only be eased to a very limited degree. PSP impairs eye movements, locomotion, balance control, and speech.

6 Feb 2017

SNAP program may be beneficial in reducing ER visits for hypoglycemia

In 2014, the Supplemental Nutrition Assistance Program, a federal program to address food insecurity in the United States, provided $70 billion in nutrition support to 46.5 million families and children living in 22.7 million American households.

1 Feb 2017

Penn researchers attempting to harness power of big data to help cancer patients avoid ER visits

What if doctors could look into a crystal ball and predict which of their patients might be at risk of getting sick enough to go to the emergency room?

30 Jan 2017

Exeter scientists discover how two cell organelles interact at molecular level

Scientists have made a breakthrough in understanding how different compartments (or organelles) of human cells interact.

20 Jan 2017

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Neurotransmitter transporters are some of the most popular transport proteins in research as they play a major role in the processing of signals in the brain. A joint study by TU Wien and the Medical University of Vienna has now successfully demonstrated for the first time the structural impact of membrane lipids on medically relevant serotonin transporters.

19 Jan 2017

Study provides insights into CPEB4 gene and fatty liver disease

This condition generally leads to chronic inflammation (non-alcoholic steatohepatitis), which can trigger fibrosis, cirrhosis and ultimately liver cancer. This study on the basic biology of the liver paves the way to examine therapeutic strategies to fight and prevent fatty liver disease.

18 Jan 2017

Technology and cost barriers hinder real-time reporting of cancer patients' symptoms

Capturing real-time reports of cancer patients' symptoms between doctor's visits has proven health benefits, but technology and cost barriers are getting in the way of widespread adoption of the practice, reports a University of North Carolina Lineberger Comprehensive Cancer Center researcher.

12 Jan 2017

Study examines role of risk factors in development of ER-positive and ER-negative breast cancers

Karla Kerlikowske, MD, and team recently published a paper in the Journal of the National Cancer Institute that examined the role of common risk factors in the development of ER-positive and ER-negative breast cancers.

10 Jan 2017

Thought leaders at U-CARS meeting to explore issues related to heart recovery and regeneration

For many years, the answer to that question was unequivocally "No." But as the University of Utah School of Medicine's annual Utah Cardiac Recovery Symposium will explore on Jan. 12-13, advances in treating heart failure are giving physicians, surgeons and researchers reason to hope the deadly disease might one day be defeated.

6 Jan 2017

Indoor smoking bans reduce asthma-related ER visits among children

Emergency rooms in communities with indoor smoking bans reported a 17 percent decrease in the number of children needing care for asthma attacks, according to new research from the University of Chicago Medicine.

30 Dec 2016

New study reveals IRBIT's role in facilitating apoptosis

Billions of cells in our bodies die every day in an important process called apoptosis. Now, researchers at the RIKEN Brain Science Institute have mapped out a sequence of events that are necessary for apoptosis to occur properly.

21 Dec 2016

‘Watershed in metabolon research’ unlocks plants' secret medicinal toolbox

Metabolons, near-mythical clusters of enzymes, have been discovered for the first time. Using fluorescent tags and microscopy -- molecular movie technology - scientists have confirmed their existence, thus unlocking plants' secret medicinal toolbox.

21 Dec 2016

Anticholinergic drugs linked to increased rate of emergency department and hospital visits

Anticholinergic medications, a class of drugs very commonly used by older adults, are linked to an increased rate of emergency department and hospital utilization in the United States, according to an Indiana University Center for Aging Research, Indiana University Center for Health Innovation and Implementation Science, and Regenstrief Institute study of community-dwelling Americans age 65 and older.

21 Dec 2016

Protective effect of ER-beta more pronounced in breast cancer patients who undergo chemotherapy

It is known from previous research that the ER-beta estrogen receptor often has a protective effect. A new study from Lund University in Sweden has found that this effect is more pronounced in patients that undergo chemotherapy.

15 Dec 2016

UNIST study could open up new avenues of research in cancer treatment

The new study, by researchers from UNIST demonstrates a more holistic light-based treatment to nuke cancer cells instead of surgery. The results, reported in the September issue of the Journal of the American Chemical Society, could open up new avenues of research in cancer treatment.

14 Dec 2016

One fifth of breast cancer patients do not complete their prescribed endocrine therapy

Around 20% of breast cancer patients do not complete prescribed endocrine therapy, researchers report at the ESMO Asia 2016 Congress in Singapore.1 The study in over 5,500 women found that younger patients and those who had taken hormone replacement therapy (HRT) were less likely to adhere to their medicine.

14 Dec 2016

Duke researchers develop new cell-based drug screening test for dystonia

Duke University researchers have identified a common mechanism underlying separate forms of dystonia, a family of brain disorders that cause involuntary, debilitating and often painful movements, including twists and turns of different parts of the body.

8 Dec 2016

Endoplasmic reticulum (ER) News and Research

U-M researchers envision new ways to avoid inappropriate ER use for mild eye problems

Researchers explore role played by nicotine in grouping of nicotinic receptors within the brain

Researchers find drugs that could replicate effects of gastric bypass surgery

PERK protein could be target for development of new drugs for progressive supranuclear palsy

SNAP program may be beneficial in reducing ER visits for hypoglycemia

Penn researchers attempting to harness power of big data to help cancer patients avoid ER visits

Exeter scientists discover how two cell organelles interact at molecular level

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Study provides insights into CPEB4 gene and fatty liver disease

Technology and cost barriers hinder real-time reporting of cancer patients' symptoms

Study examines role of risk factors in development of ER-positive and ER-negative breast cancers

Thought leaders at U-CARS meeting to explore issues related to heart recovery and regeneration

Indoor smoking bans reduce asthma-related ER visits among children

New study reveals IRBIT's role in facilitating apoptosis

‘Watershed in metabolon research’ unlocks plants' secret medicinal toolbox

Anticholinergic drugs linked to increased rate of emergency department and hospital visits

Protective effect of ER-beta more pronounced in breast cancer patients who undergo chemotherapy

UNIST study could open up new avenues of research in cancer treatment

One fifth of breast cancer patients do not complete their prescribed endocrine therapy

Duke researchers develop new cell-based drug screening test for dystonia

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