Induced Pluripotent Stem Cells News and Research

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Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles.

1 Jun 2023

Developing a more effective treatment for torn tendons

Cedars-Sinai investigators are working to develop a more effective treatment for one of the most common and hard-to-heal musculoskeletal injuries: torn tendons.

27 Apr 2023

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer's disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists.

24 Apr 2023

Mount Sinai announces creation of the Institute for Regenerative Medicine

Regenerative medicine - the process of replacing, engineering or regenerating human cells, tissues or organs - holds exciting potential for the field of health care.

24 Apr 2023

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

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20 Apr 2023

Using engineered stem cells to treat ALS and retinitis pigmentosa

Cedars-Sinai investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

20 Apr 2023

Researchers reveal how a new CALM mutation causes deadly arrhythmias

Arrhythmia, when left unchecked, can be life-threatening.

18 Apr 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

Ingenious device enables construction of complex 3D organoids in a simpler way

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques.

7 Apr 2023

BU researcher wins $3.9 million NIH grant to develop novel therapeutic modalities for Alzheimer's

Julia TCW, PhD, assistant professor of pharmacology & experimental therapeutics at Boston University Chobanian & Avedisian School of Medicine, has received a five-year, $3.9 million grant from the National Institutes of Health's National Institute on Aging.

3 Apr 2023

Screening cultured stem cells for genetic mutations could ensure the accuracy of disease models

Induced pluripotent stem cells offer great therapeutic potential and are a valuable tool for understanding how different diseases develop.

24 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

Bat stem cells reveal how bats survive in a virus-filled environment

A recent Cell journal study tested the hypothesis that bats genetically induce the virus for immune evasion and provide fertile ground for replication.

15 Mar 2023

A convergent coexpression approach identifies novel genes associated with autism

The current study analyzes transcriptional convergence across many autism risk genes.

14 Mar 2023

Newly identified therapeutic target could lead to more effective treatment of glaucoma

Indiana University School of Medicine researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.

10 Mar 2023

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

Johns Hopkins Medicine researchers are collaborating with NASA to send human heart "tissue-on-a-chip" specimens into space as early as March.

7 Mar 2023

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses.

21 Feb 2023

Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types - say, heart, liver, blood, and sperm cells - possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

Researchers discuss the role of a surfactant-mediated inflammatory response employed by human lungs against SARS-CoV-2.

3 Feb 2023

Induced Pluripotent Stem Cells News and Research

Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

Developing a more effective treatment for torn tendons

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Mount Sinai announces creation of the Institute for Regenerative Medicine

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

Using engineered stem cells to treat ALS and retinitis pigmentosa

Researchers reveal how a new CALM mutation causes deadly arrhythmias

Research reveals molecular features of rare mtDNA mutations

Ingenious device enables construction of complex 3D organoids in a simpler way

BU researcher wins $3.9 million NIH grant to develop novel therapeutic modalities for Alzheimer's

Screening cultured stem cells for genetic mutations could ensure the accuracy of disease models

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Bat stem cells reveal how bats survive in a virus-filled environment

A convergent coexpression approach identifies novel genes associated with autism

Newly identified therapeutic target could lead to more effective treatment of glaucoma

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Step-by-step process of rewiring cells to generate germ cell precursors

First fully human ovarian organoids provide insights about female reproductive health and disease

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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