Kidney Failure News and Research

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Drug combinations may help to slow the progression of diabetic kidney disease

A mouse study led by Washington University School of Medicine in St. Louis suggests that combining SGLT2 inhibitors — a newer class of diabetes medications that lowers blood sugar — with older diabetes drugs may help to slow the progression of diabetic kidney disease.

15 Jun 2022

Race is often used as medical shorthand for how bodies work. Some doctors want to change that.

Several months ago, a lab technologist at Barnes-Jewish Hospital mixed the blood components of two people: Alphonso Harried, who needed a kidney, and Pat Holterman-Hommes, who hoped to give him one.

13 Jun 2022

Vaccination lowers the risk of experiencing severe COVID-19 in dialysis patients

In an analysis of patients with kidney failure receiving dialysis who had become infected with SARS-CoV-2, those who were vaccinated had a lower risk of experiencing severe COVID-19.

3 Jun 2022

Coffee consumption may reduce the risk of acute kidney injury

If you need another reason to start the day drinking a cup of joe, a recent study by Johns Hopkins Medicine researchers has revealed that consuming at least one cup of coffee a day may reduce the risk of acute kidney injury (AKI) when compared to those who do not drink coffee.

2 Jun 2022

Vaccinated people with breakthrough SARS-CoV-2 infection can experience debilitating long COVID

Even vaccinated people with mild breakthrough COVID-19 infections can experience debilitating, lingering symptoms that affect the heart, brain, lungs and other parts of the body, according to new research from Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System.

25 May 2022

Multi-country study provides a clear treatment option for IgA nephropathy

The largest ever randomized controlled trial in IgA nephropathy has found that treatment with methylprednisolone - a cheap, widely used corticosteroid drug - halves the risk of losing kidney function and kidney failure, and that this can be effectively achieved with fewer side effects if a reduced dose is used.

17 May 2022

New project aims to improve exercise adherence in hemodialysis patients

There are approximately 600,000 individuals in the U.S. who are undergoing hemodialysis (HD) therapy for kidney failure. In hemodialysis, a machine filters wastes, salts, and fluid from the blood when an individual's kidneys are no longer healthy enough to do this work adequately.

12 May 2022

Obesity progression may contribute to the economic burden of the disease, studies suggest

Obesity is known to approximately double healthcare costs in the US compared to those with a healthy weight.

2 May 2022

Researchers use a systems biology approach to parse the genetic diversity of C. difficile

Researchers at University of California San Diego School of Medicine and Jacobs School of Engineering, with colleagues at Baylor College of Medicine, have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen in health care settings.

27 Apr 2022

Study examines how race and sex influence tacrolimus pharmacokinetics in kidney transplant recipients

Kidney transplant survival is shorter, on average, in Black recipients compared to white recipients receiving similar treatment.

18 Apr 2022

Low-dose lithium attenuates kidney aging in mice

Best known therapeutically as a treatment for bipolar disorder, lithium has long intrigued researchers with its potential age-defying properties.

12 Apr 2022

Scientists are searching for the ‘perfect protein’ to develop mRNA-based malaria vaccine

After the success of mRNA vaccines against COVID-19, scientists are cautiously optimistic that the same technology can be used to tackle other widespread diseases such as malaria.

7 Apr 2022

Insomnia common in heart disease patients and linked with subsequent cardiovascular events

Nearly half of heart disease patients have insomnia, according to research presented at ESC Preventive Cardiology 2022, a scientific congress of the European Society of Cardiology, and published in SLEEP Advances.

7 Apr 2022

Severe COVID linked to RAAS and hyperlipidemia associated metabolic syndrome conditions

A recent study posted to the medRxiv* preprint server investigated the association of renin-angiotensin-aldosterone system (RAAS)-mediated hypertension (HT) with coronavirus disease 2019 (COVID-19).

6 Apr 2022

Insufficient sleep could play a role in the development of type 2 diabetes

People who have difficulty getting to sleep or staying asleep had higher blood sugar levels than people who rarely had sleep issues, new research has found.

6 Apr 2022

Novel transcatheter repair system for tricuspid regurgitation shows promising results at one year

Patients with tricuspid regurgitation, a common and debilitating form of valvular heart disease, who received a novel investigational device intended to repair the defective valve experienced significant improvements in blood flow through the heart and in quality of life at one year, according to research presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

Acute respiratory distress syndrome may increase death risk among young COVID-19 patients

A new study estimated the risk and prevalence of acute respiratory distress syndrome in hospitalized young adults with SARS-CoV-2 infection.

4 Apr 2022

Virtual population used to replicate a clinical trial that examines kidney damage in Black Americans

Researchers have successfully used a virtual population to replicate a clinical trial that examined kidney damage in Black Americans, according to a new study at the University of Mississippi Medical Center in Jackson. John S. Clemmer, PhD, a physiologist and lead author of the study, said his team model used a calcium channel blocker to predict kidney damage.

2 Apr 2022

Treating mild hypertension during pregnancy reduces the risk of adverse outcomes

Treating even mildly elevated, or non-severe, blood pressure during pregnancy reduces the risk of adverse pregnancy outcomes and is unlikely to harm the developing baby, according to a study being presented at the American College of Cardiology's (ACC) 71st Annual Scientific Session.