Lung Disease News and Research

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Perceived stress linked to worsened symptoms in COPD patients

Increased perceived stress may cause worsened respiratory symptoms and decreased quality of life in people with chronic obstructive pulmonary disease (COPD), according to a new study.

29 Apr 2025

Targeted drug zongertinib shows strong results for HER2-mutant lung cancer in clinical trial

The HER2-targeted therapy zongertinib demonstrated clinical benefits for previously treated patients with advanced HER2-mutant non-small cell lung cancer – particularly those with specific HER2 mutations – with manageable side effects, according to results from the Phase Ia/Ib Beamion LUNG-1 trial led by researchers from The University of Texas MD Anderson Cancer Center.

28 Apr 2025

HOPE technique shows promise for long-term donor lung preservation

A study on donor lungs preserved outside the body before transplantation demonstrated that the hypothermic oxygenated machine perfusion (HOPE) technique is a safe and effective lung preservation method, even with total out-of-body times approaching 20 hours.

27 Apr 2025

Heart transplant volume rises with adoption of DCD techniques

Researchers at the Annual Meeting and Scientific Sessions of the International Society of Heart and Lung Transplantation (ISHLT) marked the 10-year anniversary of modern heart donation after circulatory death (DCD), a technique that has significantly increased transplant volumes around the world.

27 Apr 2025

Machine perfusion extends long-distance heart transplant possibilities

In places like Australia, where metropolitan areas are separated by an entire continent, donor hearts used to go unused simply because transplant teams couldn't get the organ to a recipient in time.

27 Apr 2025

Hands-on training for cardiogenic shock takes center stage at ISHLT Annual Meeting

Healthcare practitioners from around the world received hands-on training for treating patients in cardiogenic shock (CS) during a first-ever simulation lab at today's Annual Meeting and Scientific Sessions of the International Society of Heart and Lung Transplantation (ISHLT) in Boston.

27 Apr 2025

Global clinical trial tests two anti-inflammatory drugs for long COVID

Spanning four continents and enrolling hundreds of people, a new clinical trial will test the effectiveness of two anti-inflammatory medicines as potential treatments for long COVID, scientists from Western University and the Schmidt Initiative for Long Covid (SILC) announced today.

24 Apr 2025

One RSV shot cuts severe lung infections in older adults for three seasons, trial shows

A phase 3 trial involving nearly 25,000 older adults across 17 countries found that a single dose of the RSVPreF3 OA vaccine reduced RSV-related lower respiratory tract disease by 63% over three seasons. Protection remained substantial despite waning, with similar efficacy to a two-dose regimen and a favorable safety profile.

23 Apr 2025

Tulane researchers identify a potential new way to treat idiopathic pulmonary fibrosis

Researchers at Tulane University have identified a potential new way to treat idiopathic pulmonary fibrosis (IPF), a deadly and currently incurable lung disease that affects more than 3 million people worldwide.

22 Apr 2025

Experimental cancer drug shows promise in boosting tuberculosis treatment

An experimental drug now in clinical trials as a cancer treatment could help boost the power of first-line tuberculosis (TB) treatments by helping infected cells die a gentler death, Johns Hopkins Medicine investigators report, based on mouse-model research of the lung-damaging disease.

21 Apr 2025

Breakthrough method allows stem cell treatment for critically ill patients on ECMO

A multidisciplinary clinical team led by Professor Bernat Soria from the Institute of Bioengineering at the Miguel Hernández University of Elche (UMH, Spain) has developed a new method to deliver cell therapies in patients on extracorporeal membrane oxygenation (ECMO), a life support system used in cases of severe lung failure.

16 Apr 2025

Promising findings for the treatment of patients with pulmonary arterial hypertension with a high risk of mortality

Pulmonary arterial hypertension (PAH) is a rare and severe lung disease with a life-threatening prognosis. After several positive trials, a recent study has confirmed the efficacy of a biotherapy, sotatercept.

16 Apr 2025

Advancing pulmonary fibrosis treatment through targeted drug delivery

Announcing a new article publication for BIO Integration journal. Pulmonary fibrosis (PF) is a progressive interstitial lung disease characterized by excessive extracellular matrix deposition and tissue scarring, and leading to impaired lung function and respiratory failure.

14 Apr 2025

Exophiala pneumonia identified in immunocompetent woman with lung disease

Exophiala, a genus of saprotrophic black fungi commonly found in the environment, is typically associated with cutaneous infections in immunocompromised hosts and rarely manifests as pneumonia.

9 Apr 2025

Breakthrough protein offers new hope for pulmonary sarcoidosis treatment

Pulmonary sarcoidosis is a lung disease characterized by granulomas-tiny clumps of immune cells that form in response to inflammation.

7 Apr 2025

Pedometers can effectively measure health and fitness

A basic pedometer can prove suffice for measuring health-promoting physical activity, according to a study comparing pedometers with more complex devices.

3 Apr 2025

Updated screening protocols could improve early diagnosis of cystic fibrosis

All states should adopt updated screening protocols so more newborns with cystic fibrosis can be diagnosed in the first weeks of life, when interventions can have the greatest benefit, according to the Cystic Fibrosis Foundation guidelines published April 2 in the International Journal of Neonatal Screening.

3 Apr 2025

Swedish researchers identify genetic variants linked to atherosclerosis

Swedish researchers have identified genetic variants that increase the risk of atherosclerosis. The aim is for these new findings to enable earlier detection of atherosclerosis and improved treatment of cardiovascular diseases such as heart attack and stroke.

31 Mar 2025

Older Americans support insurance coverage for obesity medications

A large majority of older Americans feel that health insurance – including Medicare – should cover anti-obesity medications, according to a new University of Michigan study.

27 Mar 2025

Blocking Piezo2 may offer a new therapeutic approach for pulmonary fibrotic diseases

Researchers have found a potential new way to slow the progression of lung fibrosis and other fibrotic diseases by inhibiting the expression or function of Piezo2, a receptor that senses mechanical forces in tissues including stress, strain, and stiffness.

25 Mar 2025

Lung Disease News and Research

Perceived stress linked to worsened symptoms in COPD patients

Targeted drug zongertinib shows strong results for HER2-mutant lung cancer in clinical trial

HOPE technique shows promise for long-term donor lung preservation

Heart transplant volume rises with adoption of DCD techniques

Machine perfusion extends long-distance heart transplant possibilities

Hands-on training for cardiogenic shock takes center stage at ISHLT Annual Meeting

Global clinical trial tests two anti-inflammatory drugs for long COVID

One RSV shot cuts severe lung infections in older adults for three seasons, trial shows

Tulane researchers identify a potential new way to treat idiopathic pulmonary fibrosis

Experimental cancer drug shows promise in boosting tuberculosis treatment

Breakthrough method allows stem cell treatment for critically ill patients on ECMO

Promising findings for the treatment of patients with pulmonary arterial hypertension with a high risk of mortality

Advancing pulmonary fibrosis treatment through targeted drug delivery

Exophiala pneumonia identified in immunocompetent woman with lung disease

Breakthrough protein offers new hope for pulmonary sarcoidosis treatment

Pedometers can effectively measure health and fitness

Updated screening protocols could improve early diagnosis of cystic fibrosis

Swedish researchers identify genetic variants linked to atherosclerosis

Older Americans support insurance coverage for obesity medications

Blocking Piezo2 may offer a new therapeutic approach for pulmonary fibrotic diseases

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