Progestin News and Research

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Synthetic progestin linked to breast cancer

Millions of post-menopausal women use hormone replacement therapy (HRT) as a method to reduce symptoms associated with menopause.

2 Apr 2008

Hormonal contraception for men

Hormonal contraception may become a safe, effective, and reversible form of birth control for men, according to a new study accepted for publication in the Journal of Clinical Endocrinology & Metabolism (JCEM).

26 Mar 2008

Long-term effects of synthetic progestins cause for concern

The widely used synthetic progestin medroxyprogesterone acetate (MPA) decreased endothelial function in premenopausal women in a study done at the University of Oregon.

11 Mar 2008

Risks of long-term hormone therapy continue to outweigh benefits

New results from the Women's Health Initiative (WHI) confirm that the health risks of long-term use of combination (estrogen plus progestin) hormone therapy in healthy, postmenopausal women persist even a few years after stopping the drugs and clearly outweigh the benefits.

6 Mar 2008

Cancer risk slightly higher for women in discontinued hormone treatment trial

A follow up study of participants in the Women's Health Initiative (WHI) clinical trial led by a University of North Carolina at Chapel Hill researcher has found that women who were taking the combined hormone therapy of estrogen plus progestin may have an increased risk of cancer since the intervention was stopped, compared to participants in the trial's placebo group.

6 Mar 2008

Cancer risk from HRT remains long after treatment has stopped

The results of a new study have shown that the risk of cancer associated with Hormone Replacement Therapy (HRT) continues long after a woman stops taking it.

5 Mar 2008

HRT appears to have no effect on risk and severity of rheumatoid arthritis

Although rheumatoid arthritis (RA) is more predominant in women, the reasons for this are unclear.

28 Feb 2008

Extra warning of blood clot risk with contraceptive skin patch

Drug regulators in the United States have granted approval for an additional warning to be added to the label of a popular contraceptive patch.

21 Jan 2008

Label change for Ortho Evra Contraceptive Transdermal Patch

The U.S. Food and Drug Administration (FDA) has approved additional changes to the Ortho Evra Contraceptive Transdermal (Skin) Patch label to include the results of a new epidemiology study that found that users of the birth control patch were at higher risk of developing serious blood clots, also known as venous thromboembolism (VTE), than women using birth control pills.

21 Jan 2008

The link between combined HRT use and the risk of lobular breast cancers

Postmenopausal women who take combined estrogen/progestin hormone-replacement therapy for three years or more face a fourfold increased risk of developing various forms of lobular breast cancer, according to new findings by researchers at Fred Hutchinson Cancer Research Center.

15 Jan 2008

No excess cardiovascular risk from HRT for most patients

An American Association of Clinical Endocrinologists (AACE) analysis of several studies monitoring the impact of Hormone Replacement Therapy (HRT) shows young women in early menopause may not only have no increased cardiovascular risk from the therapy, but may indeed show benefit in the future.

3 Jan 2008

Hopkins report: Next generation contraceptive implants are cheaper, highly effective, and available now

The next generation of contraceptive implants offer an extremely effective way to expand family planning choices for women and reduce the incidence of maternal mortality worldwide, according to the latest issue of Population Reports, from the Johns Hopkins Bloomberg School of Public Health.

29 Oct 2007

HRT boosts libido but not memory

Hormone therapy in early post-menopause increases sexual interest, but does not improve memory, according to a study in the Sept. 25 issue of the journal Neurology.

25 Sep 2007

Women generally unaware of landmark hormone therapy study

Despite the huge publicity generated by a 2002 study on the potential dangers of hormone therapy for postmenopausal women, new research from the Stanford University School of Medicine found that only 29 percent of women surveyed knew about the study two years later.

18 Sep 2007

Age is important in HRT use

Five years ago this summer the National Institutes of Health's stopped early a major portion of the Women's Health Initiative (WHI), a large and ambitious study to address the most common causes of death, disability and impaired quality of life in postmenopausal women.

3 Aug 2007

Link between breast cancer and hormone therapy confirmed

A sharp drop in breast cancer rates from 2003 to 2004 is linked to an even larger drop in women's use of hormone therapy that began around 2000, according to a Kaiser Permanente study in the August 1, 2007, issue of the Journal of the National Cancer Institute that confirms the connection between breast cancer, hormone therapy and mammography screening over the past 25 years.

25 Jul 2007

Breast cancer and HRT

The medical community has been debating for many years whether, and to what extent, postmenopausal hormone therapy (HT) use is associated with a higher risk of breast cancer, says Professor Amos Pines, President of the International Menopause Society.

25 Jul 2007