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Investigational knee injection targets cartilage loss in osteoarthritis patients

Keck Medicine of USC has launched a clinical trial testing the safety and tolerability of a new investigational treatment and its potential effects on preventing cartilage deterioration in people with knee osteoarthritis, the most common form of the disease.

14 Oct 2026

Finnish study finds poor oral health increases jawbone necrosis risks in breast cancer patients

Antiresorptive drugs, which reduce bone breakdown, are an important part of treatment for breast cancer that has spread to the bones. However, their use can be associated with osteonecrosis of the jaw (MRONJ), a condition in which bone tissue in the jaw dies.

14 Oct 2026

Scientists identify novel autoimmune driver behind DNA repair breakdown in childhood cancer

Researchers have found the first evidence for a previously unsuspected cause of pediatric cancer. They showed that children with such cancers were more likely than their healthy peers to produce ‘auto-antibodies’ targeting six proteins necessary for normal DNA repair. Likewise, they showed that young adults with cancer had greater amounts of these circulating antibodies already years before diagnosis.

14 Oct 2026

$5.8 million study explores gut-brain inflammation in people with HIV

Oregon Health & Science University researchers have secured a $5.8 million, five-year federal award to investigate whether damage to the gastrointestinal tract contributes to neuroinflammation in people living with HIV - raising the potential for new treatments to preserve brain function in people with HIV and older adults.

13 Oct 2026

Pancreatic cancer cells continuously reshape DNA to evade treatment

A new analysis of nearly half a million cells from dozens of pancreatic tumors, led by researchers at UC San Diego Moores Cancer Center and New York University (NYU), reveals how pancreatic cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment.

13 Oct 2026

Enhanced CAR T-cell therapy may improve treatment options for patients with B-cell blood cancers

Results from a phase I clinical trial led by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) show a possible way to improve therapy options for patients with relapsed or treatment-resistant B-cell blood cancers.

13 Oct 2026

Topical peptide spray outperforms placebo in healing burn wounds

Burn wound infections remain a major global health burden, often requiring hospitalization and delaying tissue repair.

13 Oct 2026

FDA approves new Parkinson’s drug pioneered by UVA scientists

The federal Food and Drug Administration has approved a new Parkinson's disease drug that was based on research by UVA Health scientists.

13 Oct 2026

Childhood leukemia treatment causes rapid, lasting challenges for patient families

New research in the October 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network finds that families of children receiving treatment for B-cell acute lymphoblastic leukemia (B-ALL) experience substantial and lasting challenges beginning early after diagnosis, according to a new multicenter study embedded in a Children's Oncology Group (COG) trial.

13 Oct 2026

Exercise boosts psychological wellbeing for menopausal women

Engaging in physical activity during menopause can improve depression, mood and overall quality of life, a new study led by UCL researchers has found.

13 Oct 2026

Single-cell analysis reveals how pancreatic cancer evades treatment

An analysis of nearly half a million cells from dozens of patients' tumors reveals how cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment for one of the deadliest forms of cancer.

13 Oct 2026

Gene therapy and special goggles help some blind adults detect objects again

In a phase 1 study of 10 adults with advanced retinitis pigmentosa, researchers found that optogenetic gene therapy combined with light-stimulating goggles was generally well tolerated, although one participant experienced a severe but transient ocular adverse event. Seven participants showed improved light sensitivity, while four of eight who completed behavioral testing demonstrated modest gains in visual function, providing preliminary evidence of partial vision restoration that requires confirmation in larger controlled trials.

12 Oct 2026

Experts launch Europe-wide framework to guide AI use in mental health

The first Europe-wide expert working group on Artificial Intelligence in mental health launches today to the ECNP congress in Munich, where the group will host an open discussion, setting out the potential, the problems, and possible directions for AI in psychiatry and neuroscience.

12 Oct 2026

Medical cannabis benefits for insomnia remain uncertain, Cochrane review finds

A new Cochrane review finds that existing evidence is too uncertain to determine whether medical cannabis improves sleep or daytime functioning in people with insomnia.

12 Oct 2026

Long-term anabolic steroid use linked to lasting heart damage

Long-term use of anabolic-androgenic steroids (AAS) has serious consequences for the heart, according to a new study that has been following weightlifters for nearly 10 years.

12 Oct 2026

Year-long trial finds NAD-boosting supplement fails to improve early Parkinson's symptoms

In a phase 3 randomized clinical trial involving 410 people with early Parkinson disease, 52 weeks of nicotinamide riboside supplementation increased blood NAD levels but failed to improve clinical outcomes compared with placebo. Participants receiving the supplement had modestly worse overall disease scores, although the difference was below the threshold generally considered clinically meaningful.

12 Oct 2026

Long non-coding RNAs offer new pathways to overcome cancer treatment resistance

Scientists are highlighting long non-coding RNAs (lncRNAs) as promising targets in the effort to overcome one of cancer treatment's most persistent challenges: therapeutic resistance.

12 Oct 2026

Oregon's licensed psilocybin centers prioritize safety but remain highly expensive

A new study has found that Oregon's licensed psilocybin centers largely follow recommended safety guidelines, offering reassurance about how the first regulated psilocybin programs in the U.S. function in practice - though the cost of treatment may keep it out of reach for many.

12 Oct 2026

Updated tinnitus guideline outlines research-based strategies for patient care

The American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) today published the Clinical Practice Guideline (CPG): Tinnitus Update in Otolaryngology–Head and Neck Surgery.

12 Oct 2026

Magnetically guided millirobots deliver targeted drugs to beating hearts

Johns Hopkins University engineers have created robots the size of a pencil tip intended to travel through the body to deliver medicine to infections inside a beating heart.

12 Oct 2026

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Therapy News and Research

Investigational knee injection targets cartilage loss in osteoarthritis patients

Finnish study finds poor oral health increases jawbone necrosis risks in breast cancer patients

Scientists identify novel autoimmune driver behind DNA repair breakdown in childhood cancer

$5.8 million study explores gut-brain inflammation in people with HIV

Pancreatic cancer cells continuously reshape DNA to evade treatment

Enhanced CAR T-cell therapy may improve treatment options for patients with B-cell blood cancers

Topical peptide spray outperforms placebo in healing burn wounds

FDA approves new Parkinson’s drug pioneered by UVA scientists

Childhood leukemia treatment causes rapid, lasting challenges for patient families

Exercise boosts psychological wellbeing for menopausal women

Single-cell analysis reveals how pancreatic cancer evades treatment

Gene therapy and special goggles help some blind adults detect objects again

Experts launch Europe-wide framework to guide AI use in mental health

Medical cannabis benefits for insomnia remain uncertain, Cochrane review finds

Long-term anabolic steroid use linked to lasting heart damage

Year-long trial finds NAD-boosting supplement fails to improve early Parkinson's symptoms

Long non-coding RNAs offer new pathways to overcome cancer treatment resistance

Oregon's licensed psilocybin centers prioritize safety but remain highly expensive

Updated tinnitus guideline outlines research-based strategies for patient care

Magnetically guided millirobots deliver targeted drugs to beating hearts

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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