Transcription Factors News and Research

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Study identifies 10 new genetic regions linked with Brugada syndrome

A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder associated with sudden death in young adults.

30 Mar 2022

ProteoGenix launches new XtenCHOTM Transient CHO Expression System to improve biologics development

ProteoGenix, a contract research organization specialized in biologics discovery and bioproduction, announces the launch of its XtenCHOTM Transient Expression System.

From ProteoGenix 30 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

A University of Iowa neuroscience research team has identified a fundamental biochemical mechanism underlying memory storage and has linked this mechanism to cognitive deficits in mouse models of Alzheimer's Disease and Related Dementias.

23 Mar 2022

New virus-based approach for measuring variations in gene regulatory elements

Tohoku University scientists in Japan have developed a virus-based approach for measuring variations in gene regulatory elements, called transcription factors, as conditions change in live organisms.

18 Mar 2022

Research findings may explain marked racial disparity in deaths from triple negative breast cancer

Different activity in two molecular networks could help explain why triple negative breast cancers tend to be more aggressive in African American (AA) women compared with white American (WA) women, a new study led by Johns Hopkins Kimmel Cancer Center researchers suggests.

15 Mar 2022

Scientists map key molecular changes during mouse embryogenesis

Scientists have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.

14 Mar 2022

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study.

9 Mar 2022

New micro-protein supports cell division and proliferation during nutrient scarcity

Researchers from the University of Eastern Finland and the University of Montreal (Canada) have discovered that a micro-protein, which they named Nrs1, supports cell division and proliferation when nutrients are scarce.

4 Mar 2022

UH researcher receives $2 million to develop drugs for traditionally undruggable targets in cancer

With a $2 million recruitment grant from the Cancer Prevention and Research Institute of Texas, a University of Houston researcher is setting up a lab to develop drugs that will work on traditionally undruggable targets in cancer.

2 Mar 2022

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Researchers emphasized the need to take on a holistic and unbiased approach to develop a universal vaccine for coronaviruses, including SARS-CoV-2, which is a biomedical priority during the ongoing COVID-19 pandemic.

28 Feb 2022

Melatonin as a safe and potentially life-saving treatment for COVID-19

A new study discusses the possible role of melatonin, an antioxidant and anti-inflammatory agent, in treating COVID-19.

24 Feb 2022

The logic that controls gene regulation in human cells discovered

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge can be applied to, for example, investigating cancers and other genetic diseases.

21 Feb 2022

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Codiak BioSciences, Inc., a clinical-stage biopharmaceutical company pioneering the development of exosome-based therapeutics as a new class of medicines, today announced the online publication of a new manuscript, Exosome mediated genetic reprogramming of tumor associated macrophages by exoASO-STAT6 leads to potent monotherapy anti-tumor efficacy, in the American Association for the Advancement of Science's journal, Science Advances.

18 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

First unbiased proteome scale study expands the number of known transcriptional activators

Also known as transcriptional activators for their ability to induce transcription of genes into RNA messages, these proteins are essential for the cells to function properly. Yet little is known about these proteins, and it wasn't clear how many activators there might be in human cells – until now.

11 Feb 2022

Transcription Factors News and Research

Study identifies 10 new genetic regions linked with Brugada syndrome

ProteoGenix launches new XtenCHOTM Transient CHO Expression System to improve biologics development

The different actions of CBD in SARS-CoV-2 infection

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

New virus-based approach for measuring variations in gene regulatory elements

Research findings may explain marked racial disparity in deaths from triple negative breast cancer

Scientists map key molecular changes during mouse embryogenesis

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

New micro-protein supports cell division and proliferation during nutrient scarcity

UH researcher receives $2 million to develop drugs for traditionally undruggable targets in cancer

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Melatonin as a safe and potentially life-saving treatment for COVID-19

The logic that controls gene regulation in human cells discovered

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

First unbiased proteome scale study expands the number of known transcriptional activators

Innate immune specificity is driven by the nervous system, study suggests

Researchers identify a bivalent histone-mark switch essential for angiogenesis

Antibody drug improves survival rates in canine prostate cancer model

Regulatory sequences in the genomes of mammals help explain how cancer invades normal tissues

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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