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Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It was developed and is being marketed by the pharmaceutical company Pfizer. It acts by inhibiting cGMP specific phosphodiesterase type 5, an enzyme that regulates blood flow in the penis. Since becoming available in 1998, sildenafil has been the prime treatment for erectile dysfunction; its primary competitors on the market are tadalafil (Cialis) and vardenafil (Levitra). It is frequently called the 'blue pill'.

Study of successful drug targets could hasten development of new medications

Guidance from an innovative computational approach could speed up the process and cut down the cost of new drug development, researchers from the University of Chicago Medical Center and Columbia University suggest in a study to be published in the February 2008 issue of Genome Research, available early online.

5 Feb 2008

Number of HIV cases among seniors in Puerto Rico increasing

The number of new HIV cases recorded among people ages 60 and older in Puerto Rico is increasing, the Miami Herald reports.

30 Jan 2008

FDA requests recall of True Man Sexual Energy and Energy Max

The U.S. Food and Drug Administration yesterday requested a recall of True Man Sexual Energy Nutrient Capsules and Energy Max Energy Supplement Men's Formula Capsules, illegal drug products that contain potentially harmful, undeclared ingredients.

5 Nov 2007

Medsafe warns of "natural health" hazards

The New Zealand Ministry of Health's medicines and medical devices regulator Medsafe is warning New Zealanders to be aware of what they're buying when shopping for herbal remedies, following charges brought against a Chinese herbalist in Auckland.

19 Oct 2007

Medical identity theft

Many consumers take precautions against identity theft, but what about medical identity theft?

10 Oct 2007

Sex after chronic heart failure

Although medication can help extend the lives of men with chronic heart failure, several factors associated with this disease can interfere with a person's ability to engage in and enjoy sexual activities.

4 Oct 2007

Sildenafil increases release of key reproductive hormone oxytocin

Researchers at the University of Wisconsin-Madison report this month that sildenafil increases the amount of oxytocin released by stimulation of the posterior pituitary gland, a small structure directly underneath the brain that regulates hormone levels in response to neural signals.

24 Aug 2007

FDA issues consumer warning for "True Man" or "Energy Max" products

The Food and Drug Administration (FDA) is advising consumers not to purchase or use "True Man" or "Energy Max" products promoted and sold as dietary supplements throughout the United States.

11 May 2007

Many older adults with HIV have unprotected sex

One out of three sexually active older adults infected with HIV has unprotected sex, according to a study by Ohio University researchers.

26 Apr 2007

Erectile dysfunction drugs may be better than nitroglycerin in protecting the heart after a severe heart attack

During a heart attack, the heart is deprived of oxygen, which can result in significant damage to heart muscle and tissue. After the attack, most patients require treatment to reduce and repair the damage and improve their chances of survival.

5 Mar 2007

Gene therapy to treat erectile dysfunction shows promise

The first human study using gene transfer to treat erectile dysfunction (ED) shows promising results and suggests the potential for using the technology to treat overactive bladder, irritable bowel syndrome and asthma, according to the researchers.

2 Dec 2006

Taking sildenafil will worsen sleep apnea

According to Brazilian researchers, taking Viagra (sildenafil) at bedtime may aggravate breathing problems in patients with severe obstructive sleep apnea.

4 Oct 2006

New drug sorts out premature ejaculation

According the American Urological Association, premature ejaculation affects about 20% of males in the U.S. aged 18-59.

11 Sep 2006

New understanding of how our brains process sensory information

The same chemical in the body that is targeted by the drug Viagra. also helps our brains "boot up" in the morning so we can process sights, sound, touch and other sensory information.

8 Aug 2006

Two-thirds of patients say Uprima didn't work for them

Two-thirds of patients stopped using Uprima, a drug commonly prescribed for erection problems, because they felt it wasn't effective, according to a large-scale study published in the July issue of the urology journal BJU International.

10 Jul 2006

Sildenafil boosts high altitude exercise up to 45% for some cyclists

Sildenafil (Viagra) significantly improved the cardiovascular and exercise performance measures of trained cyclists at high altitude, mostly because the drug helped some participants improve a lot -- up to 45% -- while others showed little change. Sildenafil provided no benefit at sea level.

5 Jul 2006