immunity News and Research

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How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Researchers use multiomics analysis to understand how SARS-CoV-2 variants, including Alpha, Delta, and Omicron, modulate the host's cellular responses and adapt to evade human immunity. The study highlights the potential for targeted therapies against both adaptive and innate immune responses.

25 Sep 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023

Mechanoresilient cancer cells more prone to metastasis

The ability of cancer cells to metastasize, or spread from one part of the body to another, is one of the reasons why cancer can be extremely challenging to treat.

22 Sep 2023

Cellular crosstalk between mother and offspring is more complex than expected

Scientists have known for decades that pregnancy requires a mother's body to adjust so that her immune system does not attack the growing fetus as if it were a hostile foreign invader.

22 Sep 2023

Study demonstrates novel role of Axin1 in mediating intestinal homeostasis and microbiota

A groundbreaking study conducted by Jun Sun's research team at the University of Illinois Chicago has revealed a new and critical role of Axin1 in regulating intestinal epithelial development and microbial homeostasis.

22 Sep 2023

Researchers develop novel ultrasound imaging technique to view macrophages in real time

Macrophages are little cells vital to the immune system and could possibly inform cell-based therapies for a variety of medical conditions.

22 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

A trial of a preventive HIV vaccine candidate has begun enrollment in the United States and South Africa.

20 Sep 2023

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

In a collaborative study published in The Lancet Microbe, the team of scientists, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and WEHI (Walter and Eliza Hall Institute of Medical Research), revealed MPXV-CRISPR – a powerful diagnostic tool capable of detecting MPXV in clinical samples with acute precision and at a faster rate than any other method, thanks to the power of CRISPR technology.

20 Sep 2023

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

The association between BNT162b2 vaccine and (COVID-19)-related ambulatory visits.

20 Sep 2023

Age and underlying conditions increase risk of critical outcomes for hospitalized COVID-19 patients

Whether vaccinated or not, having at least four disease risk factors put adults hospitalized due to COVID-19 at higher risk for critical outcomes, according to a 10-state study from the Centers for Disease Control and Prevention's (CDC's) VISION Network.

19 Sep 2023

Tufts Lyme Disease Initiative receives $7M in grants to advance research to next level

Researchers at the Tufts Lyme Disease Initiative recently received grants totaling more than $7 million to build on an already impressive array of discoveries that Tufts' teams have made to combat tick-borne diseases.

19 Sep 2023

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Regular and intense aerobic exercise may reduce the risk of colorectal cancer in patients with Lynch Syndrome (LS) by improving the immune system's ability to detect and remove potentially harmful cells, according to researchers at The University of Texas MD Anderson Cancer Center.

19 Sep 2023

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer.

19 Sep 2023

Study assesses duration of protection offered by smallpox infection and possible cross-reaction with Mpox virus

More than 43 years ago, many Chinese residents were vaccinated with the vaccinia virus Tiantan strain (VTT) to protect them from smallpox infection.

19 Sep 2023

Inactivated poliovirus vaccine elicits persistent immunity for up to 10 years

The neutralizing antibodies persistence of the Sabin strain-derived inactivated poliovirus vaccine.

19 Sep 2023

Can your baby's gut bacteria predict food allergies?

Researchers in Italy delve into how changes in gut microbiota during the first 1000 days of life can influence the onset of food allergies in children. The study sheds light on various factors such as birth methods, breastfeeding, and antibiotic use that impact gut health, highlighting the need for more research on effective interventions for allergy prevention.

18 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Health workers warn loosening mask advice in hospitals would harm patients and providers

Nurses, researchers, and workplace safety officers worry new guidelines from the Centers for Disease Control and Prevention might reduce protection against the coronavirus and other airborne pathogens in hospitals.

18 Sep 2023

How well do current vaccines hold up against new SARS-CoV-2 variants BA.2.86 and FLip?

The study explores the efficacy of three-dose monovalent or bivalent vaccinations in neutralizing newly emerged SARS-CoV-2 variants BA.2.86 and FLip. While BA.2.86 showed lower immune evasion abilities compared to recent XBB variants, it was less effectively neutralized by the monoclonal antibody S309, raising questions about vaccine efficacy against evolving strains.

17 Sep 2023

immunity News and Research

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Exercise boosts immune defense in Lynch syndrome patients

Mechanoresilient cancer cells more prone to metastasis

Cellular crosstalk between mother and offspring is more complex than expected

Study demonstrates novel role of Axin1 in mediating intestinal homeostasis and microbiota

Researchers develop novel ultrasound imaging technique to view macrophages in real time

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

Age and underlying conditions increase risk of critical outcomes for hospitalized COVID-19 patients

Tufts Lyme Disease Initiative receives $7M in grants to advance research to next level

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Study assesses duration of protection offered by smallpox infection and possible cross-reaction with Mpox virus

Inactivated poliovirus vaccine elicits persistent immunity for up to 10 years

Can your baby's gut bacteria predict food allergies?

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Health workers warn loosening mask advice in hospitals would harm patients and providers

How well do current vaccines hold up against new SARS-CoV-2 variants BA.2.86 and FLip?

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