Protein C News and Research

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SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

The study published in Science Advances reveals the mechanism by which the receptor tyrosine kinase RET can increase neuronal survival in degenerative diseases. To understand the mechanism of this signaling complex, the researchers solved the cryo-EM structure of its extracellular region, employing a new approach for data collection.

21 Oct 2019

Highly diluted candidate Ebola vaccine remains fully protective against disease in macaques

A single dose of a highly diluted VSV-Ebola virus vaccine--approximately one-millionth of what is in the vaccine being used to help control the ongoing Ebola outbreak in the Democratic Republic of the Congo (DRC)--remains fully protective against disease in experimentally infected monkeys, according to National Institutes of Health scientists.

18 Oct 2019

Researchers uncover novel molecular clues for tumor aggression in neurofibromatosis type 1

Researchers at the Johns Hopkins Kimmel Cancer Center report that their study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1

From Johns Hopkins Medicine 18 Oct 2019

Novel approach brings researchers one step closer to universal flu vaccine

The scourge of the influenza virus devastates health and claims many lives worldwide each year. It is especially daunting because vaccines are only protective when they are well matched to the strains circulating in the population.

18 Oct 2019

New research center will encompass a myriad of muscle science and disease investigations

With collaborating labs across the University of Washington campus and at other Seattle-area institutions and beyond, the Center for Translational Muscle Research will encompass a myriad of muscle science and disease investigations.

17 Oct 2019

Building models to reconstruct evolutionary change more accurately than ever before

Remember domain, kingdom, phylum, class, order, family, genus, species and Darwin's tree of life metaphor we learned about in high school biology? That way of describing living-things lineages is just science's best guess about how genes have mutated and split over time to change things into what they are today.

17 Oct 2019

Father’s nutritional pattern affects child’s cardiovascular health

While couples often change their lifestyle in order to conceive faster, including crash diets, a new study in mice throws up the possibility that this kind of extreme dietary modification by the father might result in adverse effects on the child conceived in this manner.

17 Oct 2019

Researchers find behavioral, biological similarities between compulsive overeating and addiction

Does yo-yo dieting drive compulsive eating? There may be a connection. According to Boston University School of Medicine researchers the chronic cyclic pattern of overeating followed by undereating, reduces the brain's ability to feel reward and may drive compulsive eating.

17 Oct 2019

Novel antibiotic-free approach to tackle superbugs

Scientists have uncovered a novel antibiotic-free approach that could help prevent and treat one of the most widespread bacterial pathogens, using nanocapsules made of natural ingredients.

17 Oct 2019

Researchers obtain 3D structural snapshots of key regulator of cell biology

Some of the greatest insights into cancer and how to treat it come when basic scientists and cancer biologists and clinicians collaborate.

17 Oct 2019

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell.

17 Oct 2019

Metabolic dysfunction found to be primary cause of Alzheimer's disease

A team of researchers led by Yale-NUS College has found evidence that metabolic dysfunction is a primary cause of Alzheimer's disease.

17 Oct 2019

Signaling defects could cause congenital heart condition

A congenital heart condition known as left ventricular non-compaction (LVNC) - which occurs when muscly projections in the embryonic heart fail to transform into compact heart muscle - could be caused by signaling defects, according to new preclinical research led by Duke-NUS Medical School in Singapore.

17 Oct 2019

New drug treats inflammation related to inherited heart disease in young athletes

When young athletes experiences sudden cardiac death as they run down the playing field, it's usually due to arrhythmogenic cardiomyopathy, an inherited heart disease.

From Johns Hopkins Medicine 17 Oct 2019

Scientists use patient-derived neurons to develop new treatment strategy for Parkinson's disease

Northwestern Medicine scientists have used patient-derived neurons to develop and test a new strategy to treat Parkinson's disease by mitigating the effects of harmful genetic mutations, as detailed in a study published today (Oct. 16) in Science Translational Medicine.

16 Oct 2019

Measuring development in young children: the DNA clock

Scientists have come up with a new discovery that could transform our understanding of how childhood growth and development are measured – the DNA clock. The study, published in the Proceedings of the National Academy of Science, is the first paper to...

16 Oct 2019

Improved antibody validation

Antibodies are used in a variety of clinical and research situations to examine the structure and function, and distribution of proteins. However, many researchers have found a lack of specificity in the functioning of these antibodies. This means that any work conducted using these antibodies will not yield reliable results.

16 Oct 2019

Protein C News and Research

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

Highly diluted candidate Ebola vaccine remains fully protective against disease in macaques

Researchers uncover novel molecular clues for tumor aggression in neurofibromatosis type 1

Novel approach brings researchers one step closer to universal flu vaccine

New research center will encompass a myriad of muscle science and disease investigations

Building models to reconstruct evolutionary change more accurately than ever before

Father’s nutritional pattern affects child’s cardiovascular health

Researchers find behavioral, biological similarities between compulsive overeating and addiction

Novel antibiotic-free approach to tackle superbugs

Researchers obtain 3D structural snapshots of key regulator of cell biology

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Metabolic dysfunction found to be primary cause of Alzheimer's disease

Signaling defects could cause congenital heart condition

New drug treats inflammation related to inherited heart disease in young athletes

Scientists use patient-derived neurons to develop new treatment strategy for Parkinson's disease

Measuring development in young children: the DNA clock

Improved antibody validation

Genetically modified cotton could help fight against malnutrition

Study shows why fatty liver disease contributes to increase in liver cancer

Brain's neural activity plays a role in human aging, life span

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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