Protein C News and Research

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Study reveals new and surprising function of adenine nucleotide translocator

Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations trigger disease has been unclear.

16 Oct 2019

Researchers identify circuit that links cigarette smoking and risk of developing diabetes

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a circuit in rats that links cigarette smoking and the risk of developing type 2 diabetes, according to a study featured on the cover of the October 17 issue of Nature.

16 Oct 2019

New discovery paves way for better treatment of diabetes

Insulin, a hormone essential for regulating blood sugar and lipids, is normally produced by pancreatic β cells. In many people with diabetes, however, pancreatic cells are not (or no longer) functional, causing a chronic and potentially fatal insulin deficiency that can only be controlled through daily insulin injections.

16 Oct 2019

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Cells undergo natural aging and death, processes that impact a multitude of cellular factors. A new Stony Brook University-led study, to be published in PNAS, provides a biophysical model that reveals how damage accumulates in the shapes of cellular proteins with age and is a trigger to death.

16 Oct 2019

New test could detect abnormal forms of protein associated with tauopathies

National Institutes of Health scientists have developed an ultrasensitive new test to detect abnormal forms of the protein tau associated with uncommon types of neurodegenerative diseases called tauopathies.

16 Oct 2019

Scientists decipher assembly line of glutamate receptors

Rapid communication of neurons in the brain, as well as the ability to learn, fundamentally rely on neurotransmitter receptors located in the contact sites of neurons, the synapses. The most important receptors in the mammalian brain are glutamate receptors of the AMPA-type that generate the electrical signal required for fast communication between neurons.

16 Oct 2019

Scientists discover novel virus that may shed light on viral evolution

Viruses are non-living creatures, consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself and continue on. But what happens if a virus lacks the proper tools to infect an organism? How can it propagate?

16 Oct 2019

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Subtle changes in the DNA of mitochondria, the tiny power plants within cells, can have profound consequences for a patient's health.

16 Oct 2019

Good news for IBS sufferers as researchers identify “gut itch”

Researchers have identified receptors that cause the pain experienced in cases of irritable bowel syndrome.

16 Oct 2019

Kids with celiac disease and allergic inflammatory disorder may not need to remove soy from their diets

Children who have both celiac disease and an associated allergic inflammatory disorder may not need to permanently remove soy from their diets to reduce scarring in the esophagus, according to new research from the University of Chicago Medicine.

16 Oct 2019

Scientists discover how malaria switched host from African gorillas to humans

Researchers have revealed the series of events that probably led to the world’s deadliest form of malaria being able to jump from ancient great apes to humans.

16 Oct 2019

Inactive receptor prevents cancer drugs from reactivating the immune system

The aim of immunotherapies is to enable the immune system once again to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose.

15 Oct 2019

Amyloid-β protein misfolding proves to be strong risk prediction marker for Alzheimer's

In symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicated a considerably higher risk of Alzheimer's disease - up to 14 years before a clinical diagnosis was made.

15 Oct 2019

Drug-light combination could offer better control over CAR T-cell treatments

Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control.

15 Oct 2019

Researchers track cell family trees to discover their role in tissue scarring and liver disease

Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions.

15 Oct 2019

Koalas protect their germline cells against retroviral attack

In a new study published in the journal Cell, scientists have found that koala DNA is protected against attack by retroviruses by a special type of immune response, which distinguishes foreign DNA from the host genome and destroys it before it can proliferate. This finding could help us understand both how koalas survive these infections, and the mechanics of adaptive gene change.

15 Oct 2019

Women receive poorer heart attack treatment than men

Women receive poorer heart attack treatment than men, even when rates of diagnosis are the same, according to new research funded by the British Heart Foundation (BHF) and published in the Journal of the American College of Cardiology.

15 Oct 2019

New technique reveals how the brain responds to light signals received by the retina

In recent decades, scientists have learned a great deal about how different neurons connect and send signals to each other. But it's been difficult to trace the activity of individual nerve fibers known as axons, some of which can extend from the tip of the toe to the head.

15 Oct 2019

A protein could play key role in neurodegenerative diseases, research suggests

Research led by Queen Mary University of London and the University of Seville around one protein's role in regulating brain inflammation could improve our understanding of neurodegenerative diseases.

15 Oct 2019

Scientists develop more accurate method to find good targets for cancer immunotherapy

Ludwig Cancer Research scientists have developed a new and more accurate method to identify the molecular signs of cancer likely to be presented to helper T cells, which stimulate and orchestrate the immune response to tumors and infectious agents.

15 Oct 2019

Protein C News and Research

Study reveals new and surprising function of adenine nucleotide translocator

Researchers identify circuit that links cigarette smoking and risk of developing diabetes

New discovery paves way for better treatment of diabetes

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

New test could detect abnormal forms of protein associated with tauopathies

Scientists decipher assembly line of glutamate receptors

Scientists discover novel virus that may shed light on viral evolution

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Good news for IBS sufferers as researchers identify “gut itch”

Kids with celiac disease and allergic inflammatory disorder may not need to remove soy from their diets

Scientists discover how malaria switched host from African gorillas to humans

Inactive receptor prevents cancer drugs from reactivating the immune system

Amyloid-β protein misfolding proves to be strong risk prediction marker for Alzheimer's

Drug-light combination could offer better control over CAR T-cell treatments

Researchers track cell family trees to discover their role in tissue scarring and liver disease

Koalas protect their germline cells against retroviral attack

Women receive poorer heart attack treatment than men

New technique reveals how the brain responds to light signals received by the retina

A protein could play key role in neurodegenerative diseases, research suggests

Scientists develop more accurate method to find good targets for cancer immunotherapy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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