Abdominal Pain News and Research

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Abdominal pain is traditionally described by its chronicity (acute or chronic), its progression over time, its nature (sharp, dull, colicky), its distribution (by various methods, such as abdominal quadrant (left upper quadrant, left lower quadrant, right upper quadrant, right lower quadrant) or other methods that divide the abdomen into nine sections), and by characterization of the factors that make it worse, or alleviate it.

Avastin (bevacizumab) shows promise in phase II study of glioblastoma multiforme

Genentech, Inc. has announced that both study arms of a randomized, multi-center Phase II clinical study of Avastin (bevacizumab) administered alone or in combination with irinotecan chemotherapy demonstrated encouraging six-month progression-free survival (PFS) and objective response rate in patients with relapsed glioblastoma multiforme (GBM), the most common and aggressive type of brain cancer.

19 Nov 2007

Cethromycin achieves all endpoints in second pivotal Phase III Trial for treatment for pneumonia

Advanced Life Sciences Holdings, Inc. (Nasdaq: ADLS), today announced positive results from Trial CL-05, the second of two pivotal phase III clinical trials designed to assess the safety and effectiveness of cethromycin, a novel once-a-day oral antibiotic for the treatment of mild-to-moderate community acquired pneumonia (CAP), the sixth leading cause of death in the United States.

16 Nov 2007

Hope on the horizon for hereditary angioedema sufferers

Although there is currently no treatment approved by the Federal Drug Administration (FDA) for acute attacks of hereditary angioedema (HAE) - a genetic disease causing swelling of extremities, face and internal organs that can be life-threatening - hope is on the horizon according to a team of experts presenting the latest research at the Annual Meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Dallas.

14 Nov 2007

UK women have caught up with men in their alcohol consumption

As levels of binge drinking in the UK rise, doctors in this week's BMJ report three cases of bladder rupture in women who attended hospital with lower abdominal pain.

13 Nov 2007

Dengue fever vaccine looks very promising

The vaccine Tetravalent is manufactured by drug company Sanofi who say it will be ready to be submitted for approval by the year 2012.

7 Nov 2007

Minority patients prefer optical colonoscopy for colorectal cancer screening

The clinical importance of colorectal cancer screening is well established, however the majority of eligible people do not undergo screening tests.

2 Nov 2007

Is it pancreatitis in acute abdominal pain in acute viral hepatitis?

Hepatitis viruses have a strong tropism for hepatocytes; viral antigen also has been detected in pancreas and gallbladder.

1 Nov 2007

Smoked salmon dip recalled because of Listeria contamination

The Food and Drug Administration in the U.S. has alerted retailers and the public over food suspected of being contaminated with Listeria monocytogenes.

30 Oct 2007

Canadian beef the culprit in E.coli outbreaks in U.S. and Canada

The Canadian Food Inspection Agency (CFIA) has issued a warning to the public regarding various beef products.

29 Oct 2007

Lidocaine lollipop helps prepare for upper GI endoscopy

Researchers at the American University of Beirut Medical Center (AUBMC) in Lebanon have found that administering a lidocaine lollipop as a single-agent anesthetic to patients undergoing an upper gastrointestinal (GI) endoscopy procedure eliminated the need for sedation in the majority of patients.

17 Oct 2007

Study evaluates safety, efficacy and tolerability of probiotics for irritable bowel syndrome

A new analysis of randomized controlled trials evaluating probiotics in the treatment of irritable bowel syndrome (IBS) has found that Bifantis, Bifidobacterium infantis 35624, the sole ingredient in Align (manufactured by Procter & Gamble), is the only probiotic currently able to demonstrate significant improvement in IBS symptoms based upon a properly designed research study.

16 Oct 2007

Hospital chairman quits over superbug scandal

Following a report that as many as 345 patients may have died from an infection contracted at a British hospital, the chairman of the hospital trust at the centre of the infection scandal has resigned.

16 Oct 2007

GERD can masquerade as persistent cough or even severe chest pain

Many people may not realize that symptoms such as chronic cough or chest pain can be caused by acid reflux into the esophagus, because they do not experience classic heartburn symptoms or acid regurgitation.

16 Oct 2007

Eating raw fish raises potential health concerns

Two case studies from Japan presented at the 72nd Annual Meeting of the American College of Gastroenterology point to a potential health problem in the United States, as more Americans consume raw fish in the form of sushi and sashimi. Anisakiasis (round worm) is a human parasitic infection caused by the consumption of raw or undercooked seafood containing Anisakis larvae.

16 Oct 2007

Capsule endoscopy finds undiagnosed Crohn's disease

A small capsule that takes "snapshots" of the small intestine as it moves through the digestive tract helped doctors spot cases of Crohn's disease that had gone undiagnosed for up to 15 years, according to researchers at Wake Forest University Baptist Medical Center.

16 Oct 2007

Cause and clinical outcome of portal vein thrombosis

Among the 118 patients with portal vein thrombosis, noncirrhotic and nontumoral extrahepatic portal vein obstruction are young and present with well tolerated bleed.

15 Oct 2007

FDA warns consumers not to consume Organic Pastures raw cream

The U.S. Food and Drug Administration (FDA) is warning consumers not to drink or consume raw (unpasteurized) cream labeled as "ORGANIC PASTURES Grade A RAW CREAM" in one-pint plastic bottles coded "SEP 14" through "SEP 21."

24 Sep 2007

Common abdominal pain may be due to a potentially treatable newly recognized inflammatory reaction

As many as one in four people in westernized countries experience pain or discomfort in their upper abdomen, and physicians have almost nothing to offer except anti-acid medicines, which usually don't work.

20 Sep 2007

FDA accepts Sucampo's sNDA for Lubiprostone for the treatment of irritable bowel syndrome

Sucampo Pharmaceuticals, Inc., has announced that the supplemental New Drug Application (sNDA) for lubiprostone (8 mcg, oral gel capsules, twice daily) for the treatment of irritable bowel syndrome with constipation (IBS-C) has been accepted for review by the U.S. Food and Drug Administration (FDA).

18 Sep 2007