Liver News and Research

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Multi-regional sampling uncovers hidden complexity in liver cancer

A study led by clinician-scientists and scientists from the National Cancer Centre Singapore (NCCS) and A*STAR's Genome Institute of Singapore (GIS) and funded by the National Research Foundation Singapore (NRF) has discovered unexpected molecular heterogeneity even within the same liver tumors. More than 40% of HCC harbors more than one molecular subtype within the same tumor and in these, the clinical outcomes for the patients are best predicted by the most aggressive subtype.

25 Jun 2024

Personal choices drive young adults' alcohol abstinence with cannabis as a common substitute

Personal decisions, such as disinterest and avoiding drunkenness, are the primary reasons young adults abstain from alcohol, with financial concerns also playing a significant role, according to a recent study.

24 Jun 2024

Scientists discover link between birthweight and risk of health complications from childhood obesity

Scientists at the University of Copenhagen discover a link between birthweight and the risk of health complications from obesity during childhood.

24 Jun 2024

Brazilian researchers identify possible biomarkers associated with recurrence of vivax malaria

The most common type of malaria in Brazil is caused by the parasite Plasmodium vivax. Although vivax malaria is milder than the variant caused by P. falciparum, the ability of P. vivax to produce dormant forms in the host's liver that can be reactivated months after the end of treatment makes it very hard to control.

24 Jun 2024

Targeting the gut microbiome: A new approach to treating diabetes

Researchers review the role of gut microbiota in the pathogenesis and management of diabetes mellitus.

24 Jun 2024

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Liver transplants associated with alcohol-related disease are growing at a rapid pace, shifting research to address pathologies behind the ailments in light of a limited supply of organ donors.

21 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

How micro- and nanoplastics may worsen non-communicable diseases

Researchers review and assess the potential exacerbation of non-communicable diseases by micro- and nanoplastics.

21 Jun 2024

Research finds microplastics in human penile tissue

The accumulation of microplastics in penile tissue to determine potential toxicity concerns.

21 Jun 2024

Role of SMIM1 gene in obesity uncovered

Scientists have discovered a new cause of why people who lack a specific blood group are genetically predisposed to be overweight or obese.

20 Jun 2024

Challenges in treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a rare progressive liver disease that damages bile ducts and significantly increases the risk of bile duct cancer, particularly a type called cholangiocarcinoma (CCA).

20 Jun 2024

Study reveals genetic associations between coffee and harmful health outcomes such as obesity and substance use

Scientists have found consistent positive genetic correlations of coffee intake with substance use and obesity in US and UK adults of European ancestry.

20 Jun 2024

Doctors may soon be able to use AI for cancer detection

A new paper in Biology Methods & Protocols, published by Oxford University Press, indicates that it may soon be possible for doctors to use artificial intelligence (AI) to detect and diagnose cancer in patients, allowing for earlier treatment.

20 Jun 2024

Early management of gestational diabetes can prevent maternal and child health complications

Speaking at the American Diabetes Association 84th Scientific Sessions, authors of a new Lancet Series challenge current approaches to managing gestational diabetes (a type of diabetes that can be diagnosed during pregnancy) and call for initiating treatment much earlier to prevent complications during pregnancy and beyond.

19 Jun 2024

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

It's been enormously difficult to pinpoint the cause of many cancers - and many seem to have more than one origin. Fibrolamellar carcinoma (FLC), however, is one that scientists thought they had nailed down.

18 Jun 2024

Study: Hepatitis E virus may be both sexually transmitted and linked to male infertility

Discovering that hepatitis E virus is associated with sperm in pigs suggests the virus may be both sexually transmitted and linked to male infertility, according to a new study.

18 Jun 2024

Safety-focused summary of GLP-1 receptor agonists in diabetes, obesity, and beyond

A recent review in Diabetes Care evaluates the efficacy and safety of GLP-1 receptor agonists for type 2 diabetes and obesity, exploring their potential for new medical indications.

18 Jun 2024

How ketone bodies contribute to brain health and memory preservation

The ketogenic diet has its fanatics and detractors among dieters, but either way, the diet has a scientifically documented impact on memory in mice.

17 Jun 2024

Study reveals doubling of chronic hypertension in pregnancy from 2008 to 2021 in the U. S.

The number of individuals in the U.S. who had chronic hypertension or chronic high blood pressure during pregnancy doubled between 2008 and 2021, while the prescribing and filling of antihypertensive medication during pregnancy remained low but stable at 60%, according to new research published today in Hypertension, a peer-reviewed journal of the American Heart Association.

17 Jun 2024

Study reveals individual differences in fasting-induced ketosis and its health benefits

The study reveals that long-term fasting-induced ketosis varies among individuals and is influenced by factors like age, gender, and physical activity. It can also guide personalized fasting strategies.

16 Jun 2024

Liver News and Research

Multi-regional sampling uncovers hidden complexity in liver cancer

Personal choices drive young adults' alcohol abstinence with cannabis as a common substitute

Scientists discover link between birthweight and risk of health complications from childhood obesity

Brazilian researchers identify possible biomarkers associated with recurrence of vivax malaria

Targeting the gut microbiome: A new approach to treating diabetes

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

New insights into signaling pathways and resistance mechanisms in colorectal cancer

How micro- and nanoplastics may worsen non-communicable diseases

Research finds microplastics in human penile tissue

Role of SMIM1 gene in obesity uncovered

Challenges in treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis

Study reveals genetic associations between coffee and harmful health outcomes such as obesity and substance use

Doctors may soon be able to use AI for cancer detection

Early management of gestational diabetes can prevent maternal and child health complications

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

Study: Hepatitis E virus may be both sexually transmitted and linked to male infertility

Safety-focused summary of GLP-1 receptor agonists in diabetes, obesity, and beyond

How ketone bodies contribute to brain health and memory preservation

Study reveals doubling of chronic hypertension in pregnancy from 2008 to 2021 in the U. S.

Study reveals individual differences in fasting-induced ketosis and its health benefits

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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