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Research contributes to better understanding of cancer cell regulation

A team of cancer researchers from the University of Liverpool, has made an important contribution to our understanding of cancer cell regulation which could better inform future cancer treatments.

10 Jan 2018

Researchers discover why exercise is good and high blood pressure is bad for the heart

When the heart is put under stress during exercise, it is considered healthy. Yet stress due to high blood pressure is bad for the heart. Why? And is this always the case? Researchers of the German Centre for Cardiovascular Research and of Heidelberg University Hospital have obtained new findings which indicate that a previously undetected signal pathway causes or protects from heart failure - depending on the type of stress.

9 Jan 2018

Choosing The Correct Camera for Fluorescence Microscopy

It is important to select the proper camera for fluorescence microscopy which has high sensitivity and low noise, to avoid photo bleaching your sample. A monochrome camera is also preferred for fluorescence imaging because it does not have a color filter pattern superimposed over the image sensor. Since the microscope’s filter wheel selects which wavelength makes its way to the sensor, a monochrome camera allows equal signal detection on all pixels and increases the overall sensitivity of the camera.

9 Jan 2018

Oncologists discover cell type that gives rise to soft tissue cancer in children

St. Jude Children's Research Hospital oncologists have discovered the cell type that gives rise to rhabdomyosarcoma, the most prevalent soft tissue cancer in children.

8 Jan 2018

Powerful imaging technique sheds light on how the brain responds to vascular injury

Pericytes, a little-understood type of cell on the brain's blood vessels, grow into the empty space left when neighboring pericytes die, report researchers at the Medical University of South Carolina in a January 2nd, 2018 article in Cell Reports.

4 Jan 2018

Advanced live cell imaging reveals brain’s response to blood vessel injury

Live cell imaging and laser beam ablation reveals the damage response of pericytes surrounding blood vessels in the brain.

3 Jan 2018

Researchers use Nobel prize-winning technology to zoom in and see vital kidney protein

Researchers have applied Nobel prize-winning microscope technology to uncover an ion channel structure that could lead to new treatments for kidney stones.

3 Jan 2018

Research provides insights into reactive and proactive aggression in childhood

Over the past few months, many local cases of assault and harassment have come to light and been widely discussed in the news, both here and in the U.S. and Europe.

21 Dec 2017

Stem cells remain healthy following low-dose X-ray exposure, say biophysicists

Biophysicists have shown that following low-dose exposure to X-rays (at 80 milligrays), stem cells remain healthy, proliferate, and do not accumulate DNA damage to be passed on to their progeny. The paper was published in the journal Aging.

20 Dec 2017

Advances in BioAFM

AFM is quite a versatile technique and we see a great potential of this technology for life science applications. It is still fairly new in Bio community, however very well accepted not only as imaging tools but as a versatile instrument for nanomechanical measurements.

From Bruker Nano Surfaces and Metrology 19 Dec 2017

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

Scientists use AI-enhanced microscope system to quickly, accurately identify bacteria

Microscopes enhanced with artificial intelligence could help clinical microbiologists diagnose potentially deadly blood infections and improve patients' odds of survival, according to microbiologists at Beth Israel Deaconess Medical Center

15 Dec 2017

New insights into mosquito sex protein could provide strategies to control diseases

If you thought the sex lives of humans were complicated, consider the case of the female Aedes aegypti mosquito, bringer of Zika, dengue, and yellow fever: She mates but once, in seconds and on the wing, with one lucky male; spurns all further advances from other potential suitors; and stores enough sperm from that single encounter to lay more than 500 eggs, which she nourishes with the blood of human hosts.

13 Dec 2017

Novel ‘black box’ recorder captures surgeons' robotic surgery skills

You may know that your surgeon is using the latest minimally invasive technology for your surgery, but how do you know if they've mastered it? To help answer that question, researchers at Keck Medicine of USC looked to a custom recording tool similar in concept to a flight recorder on an airplane.

13 Dec 2017

Live-cell microscopy reveals internal forces that direct cell migration

Two new studies conducted at the Marine Biological Laboratory (MBL) indicate the way by which cells react to internal forces when they orient, gain traction, and migrate in a particular direction.

11 Dec 2017

Mount Sinai study uses adaptive optics to examine retinal eye damage from solar eclipse

In a first-of-its-kind study, Mount Sinai researchers are using adaptive optics (AO) to analyze retinal eye damage from the August solar eclipse on a cellular level. The research could help doctors develop a deeper understanding of this rare condition, called solar retinopathy, which has no currently accepted treatment.

8 Dec 2017

Congenital heart disease patients more likely to suffer from atrial fibrillation

Patients with congenital heart disease are up to 85 times more likely to suffer from atrial fibrillation as adults. The researchers behind a study, published in the journal Circulation, are now advocating more frequent screenings of the most vulnerable groups.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Innovative technique makes low-grade gliomas visible

Gliomas are a type of brain tumor characterized by a poor prognosis. In order to improve this prognosis, as much of the tumor as possible must be removed safely during the neurosurgical operation.

4 Dec 2017

Researchers discover ‘brake’ that interferes with HIV's development into infectious agent

Viewed with a microscope, the virus faintly resembles a pineapple--the universal symbol of welcome. But HIV, the virus that causes AIDS, is anything but that. It has claimed the lives of more than 35 million people so far.

1 Dec 2017