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Could soluble CD24 offer some hope against severe COVID-19?

A recent randomized phase III trial conducted by researchers at the Ohio State University, Columbus, OH, US, evaluated the impact of CD24Fc in severe COVID-19 patients and showed promising clinical efficacy. This study is available as a preprint on the medRxiv* server.

26 Aug 2021

Aerobic exercise combined with tDCS improves the gait of Parkinson's patients

Transcranial direct current stimulation (tDCS) can increase the benefits of aerobic exercise and improve the gait of patients with Parkinson's disease immediately after a session. Step time variability decreases, reaction time shortens, and executive control of gait is enhanced.

25 Aug 2021

Lipid-lowering drug TriCor dramatically cuts treatment time for severe COVID-19 patients

The SARS-CoV-2 virus has infected over 165 million people worldwide causing nearly 3.5 million deaths. Recent vaccination efforts have been hindered by multiple coronavirus variants that challenge current vaccines.

23 Aug 2021

Hidradenitis suppurativa: Discontinuation of adalimumab prior to surgery is not necessary

Hidradenitis suppurativa (Syn. Acneinversa) is one of the most troublesome and complicated skin diseases. The anti-inflammatory drug adalimumab can improve symptoms; however, patients also often have to undergo surgery.

19 Aug 2021

Phase I clinical study evaluates safety and pharmacokinetics of ExeVir's COVID-19 neutralizing antibody

ExeVir, which is developing single domain antibody therapies providing broad protection against viral infections, today announces that the first subjects have been dosed in a Phase I clinical study of XVR011, its llama-derived antibody for the treatment and prevention of COVID-19.

19 Aug 2021

Convalescent plasma does not benefit high-risk COVID-19 outpatients with early symptoms, study shows

The final results of the Clinical Trial of COVID-19 Convalescent Plasma in Outpatients (C3PO) demonstrate that COVID-19 convalescent plasma did not prevent disease progression in a high-risk group of outpatients with COVID-19, when administered within the first week of their symptoms.

18 Aug 2021

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

The safety, immunogenicity, and efficacy of the vaccines in adolescents are largely unknown. Now, a new study published in the New England Journal of Medicine evaluates the safety and efficacy of the mRNA-1273 vaccine in adolescents (12-17 years of age).

16 Aug 2021

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

Scientists with the Ajmera Transplant Centre at UHN have conducted a first-in-the-world randomized placebo-controlled trial of third dose COVID-19 booster vaccine for transplant patients that shows substantially improved protection.

14 Aug 2021

UC Davis joins with Pfizer for COVID-19 booster vaccine trial

As COVID-19 booster shots begin for those with compromised immune systems, researchers at the UC Davis School of Medicine continue to collect data from clinical trial participants.

13 Aug 2021

FDA approves a new indication for chronic sleep disorder treatment

The U.S. Food and Drug Administration today approved a new indication for Xywav for idiopathic hypersomnia (IH) in adults.

12 Aug 2021

Antiviral activity of lipid-modified remdesivir in comparison to common remdesivir

In new research, scientists evaluated the broad-spectrum antiviral activity of ODBG-P-RVn, an orally available, lipid-modified monophosphate prodrug of the remdesivir parent nucleoside (GS-441524) against viruses that cause diseases of human public health concern, including SARS-CoV-2.

10 Aug 2021

Oral drug found to be effective, safe for treating anemia in patients with chronic kidney disease

Pooled results from recent clinical trials indicate that an oral drug called roxadustat is an effective treatment for anemia in patients with chronic kidney disease.

6 Aug 2021

Study examines the effect of vitamin D supplementation on kidney health in adults with prediabetes

A recent clinical trial described in CJASN has examined the potential of vitamin D supplementation for protecting the kidney health of individuals with pre-diabetes.

6 Aug 2021

Vitamin D supplementation could reduce opioid doses in palliative cancer treatment

Patients with vitamin D deficiency who received vitamin D supplements had a reduced need for pain relief and lower levels of fatigue in palliative cancer treatment, a randomized and placebo-controlled study by researchers at Karolinska Institutet in Sweden shows.

5 Aug 2021

Common weight-loss drug successfully targets fat in adults with obesity at high cardiovascular risk

Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide.

4 Aug 2021

Study examines efficacy Pfizer-BioNTech vaccine among USAF Academy Cadets

A new study published on the medRxiv* preprint server has estimated the effectiveness of vaccines in preventing COVID-19 as a function of time since vaccination.

3 Aug 2021

Pfizer moves towards an oral anti-COVID-19 therapy

Researchers in the United States have described a novel antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being evaluated in clinical trials as a treatment for coronavirus disease 2019 (COVID-19).

2 Aug 2021

Study shows safety and efficacy of radio-wave therapy for liver cancer patients

Researchers at Wake Forest School of Medicine have shown that a targeted therapy using non-thermal radio waves is safe to use in the treatment of hepatocellular carcinoma (HCC), the most common type of liver cancer.

30 Jul 2021

Diabetes drug’s new weight loss formula fuels cost-benefit debate

The long list of side effects that follow ads for the newer expensive drugs to treat Type 2 diabetes sometimes include an unusual warning: They might cause weight loss. That side effect is one that many people — especially those with Type 2 diabetes, which is associated with obesity — may desperately want.

30 Jul 2021

BNT162b2 vaccine shows high efficacy at six months

The Pfizer/BioNTech vaccine appears to be highly effective in protecting against the SARS-CoV-2 infection, including its relatively resistant beta variant B.1.351.

30 Jul 2021

Placebo News and Research

Could soluble CD24 offer some hope against severe COVID-19?

Aerobic exercise combined with tDCS improves the gait of Parkinson's patients

Lipid-lowering drug TriCor dramatically cuts treatment time for severe COVID-19 patients

Hidradenitis suppurativa: Discontinuation of adalimumab prior to surgery is not necessary

Phase I clinical study evaluates safety and pharmacokinetics of ExeVir's COVID-19 neutralizing antibody

Convalescent plasma does not benefit high-risk COVID-19 outpatients with early symptoms, study shows

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

UC Davis joins with Pfizer for COVID-19 booster vaccine trial

FDA approves a new indication for chronic sleep disorder treatment

Antiviral activity of lipid-modified remdesivir in comparison to common remdesivir

Oral drug found to be effective, safe for treating anemia in patients with chronic kidney disease

Study examines the effect of vitamin D supplementation on kidney health in adults with prediabetes

Vitamin D supplementation could reduce opioid doses in palliative cancer treatment

Common weight-loss drug successfully targets fat in adults with obesity at high cardiovascular risk

Study examines efficacy Pfizer-BioNTech vaccine among USAF Academy Cadets

Pfizer moves towards an oral anti-COVID-19 therapy

Study shows safety and efficacy of radio-wave therapy for liver cancer patients

Diabetes drug’s new weight loss formula fuels cost-benefit debate

BNT162b2 vaccine shows high efficacy at six months

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

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Advancing Intracellular Delivery with LumiPore®

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