Proliferation News and Research

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Researchers create first map of microbiome of dental black plaque in adults

The dark pigmentations that appear around the gums on dental enamel have a bacterial origin and there is currently no definitive therapy to remove it entirely.

3 Dec 2020

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

The COVID-19 pandemic has led to millions of deaths across the globe. The causative agent of this disease is the novel coronavirus, SARS-CoV-2.

3 Dec 2020

The vaginal microbiome may impact the efficacy of HIV prevention therapy

A new study has revealed that vaginal microbial communities are linked with an increased risk of HIV acquisition and may also impact the efficacy of PrEP.

3 Dec 2020

Scientists report the first map of molecular responses of human lung cells to SARS-CoV-2 infection

In a multi-group collaborative involving the National Emerging Infectious Disease Laboratories (NEIDL), the Center for Regenerative Medicine (CReM), and the Center for Network Systems Biology (CNSB), scientists have reported the first map of the molecular responses of human lung cells to infection by SARS-CoV-2.

2 Dec 2020

A mutant SARS-CoV-2 subspecies from minks may evade antibody detection

In a recent research letter published on the bioRxiv preprint server, scientists from Japan discovered that the mutation of spike glycoprotein in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) derived from farmed minks can also be found in the group of individuals with coronavirus disease (COVID-19) and subsequently evade detection by our immune system.

30 Nov 2020

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Laboratory research and analysis of epidemiological data by Silvia Corvera, MD, and Tiffany Moore Simas, MD, MPH, MEd, and colleagues show that low levels of a protein commonly seen in screening tests for chromosomal disorders during the first trimester of pregnancy is associated with adipose tissue remodeling, glucose resistance and gestational diabetes mellitus in pregnant women.

30 Nov 2020

Researchers study the role of viral intramembrane interactions in controlling programmed cell death

A research group from the Department of Biochemistry and Molecular Biology of the University of Valencia (UV), in coordination with the National Centre for Biotechnology (CNB) of the CSIC, has studied the role of the interactions within the membrane of proteins of viral families Herpesviridae and Poxviridae in the control of programmed cell death.

27 Nov 2020

Mine ponds increase risk of mercury exposure for indigenous communities and wildlife

The proliferation of pits and ponds created in recent years by miners digging for small deposits of alluvial gold in Peru's Amazon has dramatically altered the landscape and increased the risk of mercury exposure for indigenous communities and wildlife, a new study shows.

27 Nov 2020

Early interferon therapy may mitigate COVID-19 severity

A recent review of COVID-19 therapies explores the utility of interferons in the battle against severe COVID-19, and concludes that they deserve further development.

26 Nov 2020

Researchers develop first plant-based gel to support organoid growth for biomedical applications

Monash University researchers have created the world's first bioactive plant-based nanocellulose hydrogel to support organoid growth and help significantly reduce the costs of studies into cancer and COVID-19.

25 Nov 2020

Researchers investigate challenges of treating acute myocardial infarction caused by variant angina

In a new publication from Cardiovascular Innovations and Applications, Wen-Yuan Ding, Jia-Min Li, Fei Zheng, Li-Li Wang, Xin-Yi Wei and Guo-Hua Li from Shandong Provincial Qianfoshan Hospital, Ji'nan, China, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji'nan, China and Shandong First Medical University, Tai'an, China consider the challenges of treating acute myocardial infarction due to variant angina.

19 Nov 2020

Analysis highlights the economic and health consequences of UTI superbugs in Australia

Analysis by national consortium, OUTBREAK, highlights how urinary tract infections (UTIs) are becoming more persistent and harder to treat, resulting in more people being admitted to hospital where they require longer stays and more costly medicines.

17 Nov 2020

Researchers report encouraging results from in vitro combination therapy against COVID-19

Researchers at Karolinska Institutet in Sweden report promising results from an in vitro combination therapy against COVID-19.

17 Nov 2020

Researchers identify two key biomarkers contributing to gastric cancer metastasis

A research team led by Professor Wang Wen-ching of the Institute of Molecular and Cellular Biology, National Tsing Hua University has exploited the power of big data to identify two key biomarkers contributing to the proliferation and metastasis of gastric (stomach) cancer.

17 Nov 2020

Goblet cells are prime target for SARS-CoV-2, study finds

A recent study reports that in the airway of patients with chronic obstructive pulmonary disease (COPD), a type of airway epithelial cell – called a goblet cell – presents a prime target for the virus and plays a vital role in promoting viral replication in this tissue.

16 Nov 2020

New cancer study may result in more effective treatments

For decades, scientists and doctors have been searching for a cure for cancer. Now, researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have taken a significant step forward with a new concept that could ultimately result in more effective treatments.

15 Nov 2020

SARS-CoV-2-induces temporary loss of smell in mice

Now, a new study published on the preprint server bioRxiv in November 2020 presents the onset of olfactory dysfunction (loss of smell) in mice infected with the virus, examining this process at the cellular level. In doing so, this study throws more light on this curious symptom and COVID-19’s manifestations outside the lungs.

12 Nov 2020

Pollution may bear part of the blame for rapid spread SARS-CoV-2 in the U.S.

The United States may have set itself up for the spread of a pandemic without even knowing it.

12 Nov 2020

Study explores connection between internal biological clocks and beta cell regeneration

Certain parts of our body, such as the skin or liver, can repair themselves after a damage. Known as cell regeneration, this phenomenon describes how cells that are still functional start to proliferate to compensate for the loss.

12 Nov 2020

Research shows a unique T cell receptor repertoire in MIS-C patients

Children with coronavirus disease 2019 (COVID-19) sometimes develop the Multisystem Inflammatory Syndrome in Children (MIS-C), which is associated with high morbidity. The underlying T-cell associated mechanism is described by researchers in a new study published on the preprint server bioRxiv in November 2020, as a response to superantigen activation.

11 Nov 2020

Proliferation News and Research

Researchers create first map of microbiome of dental black plaque in adults

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

The vaginal microbiome may impact the efficacy of HIV prevention therapy

Scientists report the first map of molecular responses of human lung cells to SARS-CoV-2 infection

A mutant SARS-CoV-2 subspecies from minks may evade antibody detection

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Researchers study the role of viral intramembrane interactions in controlling programmed cell death

Mine ponds increase risk of mercury exposure for indigenous communities and wildlife

Early interferon therapy may mitigate COVID-19 severity

Researchers develop first plant-based gel to support organoid growth for biomedical applications

Researchers investigate challenges of treating acute myocardial infarction caused by variant angina

Analysis highlights the economic and health consequences of UTI superbugs in Australia

Researchers report encouraging results from in vitro combination therapy against COVID-19

Researchers identify two key biomarkers contributing to gastric cancer metastasis

Goblet cells are prime target for SARS-CoV-2, study finds

New cancer study may result in more effective treatments

SARS-CoV-2-induces temporary loss of smell in mice

Pollution may bear part of the blame for rapid spread SARS-CoV-2 in the U.S.

Study explores connection between internal biological clocks and beta cell regeneration

Research shows a unique T cell receptor repertoire in MIS-C patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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