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AstraZeneca reports fostamatinib Phase 3 study results for treatment of rheumatoid arthritis

AstraZeneca today announced top-line results of OSKIRA-1, a Phase 3 study to assess the efficacy and safety of fostamatinib, the first oral spleen tyrosine kinase inhibitor in development for rheumatoid arthritis.

6 Apr 2013

Walgreens' Take Care Clinics expand access to health care services

Access to health care services is an ongoing challenge to the U.S. health care system. With a physician shortage, aging population, a growing prevalence of chronic diseases and up to 30 million people projected to gain insurance coverage in 2014 through the Affordable Care Act, the issue will become even more critical - and may further impact both patients and the health care system at large.

4 Apr 2013

Researchers identify vulnerability of lung-cancer cells that can be exploited for new therapies

Physician-researchers at UT Southwestern Medical Center have identified a vulnerability of certain lung-cancer cells - a specific genetic weakness that can be exploited for new therapies.

4 Apr 2013

Clinical trial signals new era in treatment of neurodegererative disorders

The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis - blocking production of a mutant protein that causes an inherited form of the progressive neurodegererative disease - may be a first step towards a new era in the treatment of such disorders.

4 Apr 2013

V/Q imaging can detect early stages of COPD

In vivo ventilation/perfusion (V/Q) imaging can detect early changes to the lung caused by cigarette smoke exposure and provides a noninvasive method for studying lung dysfunction in preclinical models, according to research published in the April issue of The Journal of Nuclear Medicine.

2 Apr 2013

HAP caused by exposure to biomass fuels increases mortality risk

Almost four million people die each year from household air pollution (HAP) caused by exposure to the combustion of biomass fuels (wood, charcoal, crop residues, and dung), kerosene, or coal.

2 Apr 2013

Post-disinfection clips retain aerobic and anaerobic bacteria, says study

Researchers at Tufts University School of Dental Medicine and the Forsyth Institute published a study today that found that a significant proportion of dental bib clips harbored bacteria from the patient, dental clinician and the environment even after the clips had undergone standard disinfection procedures in a hygiene clinic.

2 Apr 2013

BioCryst Pharmaceuticals receives preliminary comment letter from FDA on peramivir

BioCryst Pharmaceuticals, Inc. announced that it received a preliminary comment letter from the U.S. Food & Drug Administration that outlines a pathway by which BioCryst could file a New Drug Application seeking regulatory approval of intravenous (i.v.) peramivir.

1 Apr 2013

Hong Kong researchers examine health risks of new SARS-like virus

"A new coronavirus that emerged in the Middle East last fall could be deadlier than the SARS virus (Severe Acute Respiratory Syndrome), which killed 774 people between 2002 and 2003, researchers from the University of Hong Kong said ... in a study published in the Journal of Infectious Diseases this week," GlobalPost reports.

30 Mar 2013

GE Healthcare seeks approval to supply Optison to EU market from Oslo manufacturing facility

GE Healthcare today announced that it has submitted an application to amend its European Marketing Authorisation that will allow the company to manufacture Optison 0.19 mg/ml dispersion for injection within its own facility.

30 Mar 2013

FDA approves Teva's Quartette tablets for prevention of pregnancy

Teva Pharmaceutical Industries Ltd. today announced that the U.S. Food and Drug Administration has approved Quartette (levonorgestrel/ethinyl estradiol and ethinyl estradiol) tablets for the prevention of pregnancy.

30 Mar 2013

Studies examine existing opportunity to improve interventions, outcomes of TBI in older adults

Considerable opportunity exists to improve interventions and outcomes of traumatic brain injury in older adults, according to three studies published in the recent online issue of NeuroRehabilitation by researchers from the Icahn School of Medicine at Mount Sinai.

30 Mar 2013

Low anterior cingulate activity linked to repeat offenses

A new study conducted by The Mind Research Network in Albuquerque, N.M., shows that neuroimaging data can predict the likelihood of whether a criminal will reoffend following release from prison.

29 Mar 2013

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation can be thought of as taking two major forms: acute or chronic. Acute inflammation, which can be painful, usually arises quickly and resolves quickly. It accompanies bacterial infections, traumatic injury and is useful to fight infections and promote healing.

28 Mar 2013

FDA accepts Merck's BLA for investigational Timothy grass pollen AIT

Merck, known as MSD outside the United States and Canada, today announced that the Biologics License Application for its investigational Timothy grass pollen (Phleum pratense) allergy immunotherapy tablet has been accepted for review by the U.S. Food and Drug Administration.

28 Mar 2013

IDIBELL signs agreement with Histocell to use patent for acute pulmonary diseases with stem cells

The Bellvitge Biomedical Research Institute has signed a licensing agreement with the Spanish biotech company Histocell to make use of a patent for the treatment of acute pulmonary diseases with mesenchymal stem cells.

28 Mar 2013

Study links genetic variation, wheezing illness to childhood asthma risk

About 90 percent of children with two copies of a common genetic variation and who wheezed when they caught a cold early in life went on to develop asthma by age 6, according to a study to be published March 28 by the New England Journal of Medicine.

28 Mar 2013

New data reveals impact of opioid-related adverse events on length, cost of hospitalization after surgery

Pacira Pharmaceuticals, Inc. today announced data from a large-scale analysis of a national database of patients from 380 hospitals in the United States who underwent 319,898 inpatient surgeries and received opioids for postsurgical pain management.

27 Mar 2013

Study shows benefit of azithromycin in patients with non-CF bronchiectasis

Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic azithromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to a study appearing in the March 27 issue of JAMA.

27 Mar 2013

Erythromycin may provide benefit for patients with non-CF bronchiectasis

Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic erythromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to a study appearing in the March 27 issue of JAMA.

27 Mar 2013

Respiratory News and Research

AstraZeneca reports fostamatinib Phase 3 study results for treatment of rheumatoid arthritis

Walgreens' Take Care Clinics expand access to health care services

Researchers identify vulnerability of lung-cancer cells that can be exploited for new therapies

Clinical trial signals new era in treatment of neurodegererative disorders

V/Q imaging can detect early stages of COPD

HAP caused by exposure to biomass fuels increases mortality risk

Post-disinfection clips retain aerobic and anaerobic bacteria, says study

BioCryst Pharmaceuticals receives preliminary comment letter from FDA on peramivir

Hong Kong researchers examine health risks of new SARS-like virus

GE Healthcare seeks approval to supply Optison to EU market from Oslo manufacturing facility

FDA approves Teva's Quartette tablets for prevention of pregnancy

Studies examine existing opportunity to improve interventions, outcomes of TBI in older adults

Low anterior cingulate activity linked to repeat offenses

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

FDA accepts Merck's BLA for investigational Timothy grass pollen AIT

IDIBELL signs agreement with Histocell to use patent for acute pulmonary diseases with stem cells

Study links genetic variation, wheezing illness to childhood asthma risk

New data reveals impact of opioid-related adverse events on length, cost of hospitalization after surgery

Study shows benefit of azithromycin in patients with non-CF bronchiectasis

Erythromycin may provide benefit for patients with non-CF bronchiectasis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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