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Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

A new study examines whether recent changes in the use of anemia drugs for patients on dialysis have contributed to changes in rates of death or cardiovascular events. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, indicate that these risks appear to be decreasing for patients on dialysis as well as for older adults (Medicare beneficiaries) who are not on dialysis.

27 Feb 2016

TTR protein causes autoimmune reaction in joints of juvenile idiopathic arthritis patients

Juvenile idiopathic arthritis, or JIA, is the most common form of childhood arthritis. It appears to be an autoimmune disease, caused by antibodies attacking certain proteins in a person's own tissue. But no "autoantigens" -- the proteins triggering an immune attack -- have been linked to JIA.

27 Feb 2016

Novartis announces FDA approval of Afinitor for progressive, nonfunctional neuroendocrine tumors of GI

Novartis today announced that the United States Food and Drug Administration approved Afinitor (everolimus) tablets for the treatment of adult patients with progressive, well-differentiated, nonfunctional neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin that are unresectable, locally advanced or metastatic.

26 Feb 2016

Homeless adults have more geriatric conditions than those living in homes

Homeless people in their fifties have more geriatric conditions than those living in homes who are decades older, according to researchers at UC San Francisco who are following 350 people who are homeless and aged 50 and over, in Oakland.

26 Feb 2016

Lilly announces CHMP positive opinion for ixekizumab for treatment of adults with plaque psoriasis

Eli Lilly and Company announced today that the European Medicines Agency's Committee for Medicinal Products for Human Use has issued a positive opinion for ixekizumab for the treatment of moderate-to-severe plaque psoriasis in adults in the European Union who are candidates for systemic therapy.

26 Feb 2016

EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

AbbVie, a global biopharmaceutical company, today announced the European Medicines Agency has granted Orphan Drug Designation to venetoclax, an investigational, oral B-cell lymphoma-2 (BCL-2) inhibitor, for the treatment of acute myeloid leukemia (AML).

26 Feb 2016

New ways to monitor physical activity at workplace

The science of physical activity at work remains understudied despite widespread acceptance that it plays an important role in health. Now, researchers at the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus have published a comprehensive review of ways to monitor physical activity and tools for occupational exposure scientists.

26 Feb 2016

Digital health: the future for medicine?

"The best way to predict the future is to invent it," these were the words of Alan Kay quoted by Dr Euan Ashley at the Recent Developments in Digital Health 2016 event at the Royal Society of Medicine. No one exemplified this inspirational message further than Professor Tony Young, National Clinical Director for Innovation, NHS England.

26 Feb 2016

Protein p62 acts as molecular brake to keep inflammation in check, avoid collateral damage

Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as p62 acts as a molecular brake to keep inflammation in check and avoid collateral damage.

26 Feb 2016

New review suggests solutions that can help ease chronic pain in women

Women often suffer silently when in pain, whether it's caused by pregnancy discomfort or creaky knees. Yet there are a variety of solutions that can help relieve women of chronic pain, from exercise to identifying triggers, suggests a new review of research related to women and pain by the American Society of Anesthesiologists.

26 Feb 2016

Baxalta seeks FDA approval for ADYNOVATE to treat children with hemophilia A and for use in surgical settings

Baxalta Incorporated, a global biopharmaceutical leader dedicated to delivering transformative therapies to patients with orphan diseases and underserved conditions, announced today that it has submitted supplemental Biologics License Applications (sBLAs) to the U.S. Food and Drug Administration seeking approval for the use of ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated] to treat children under the age of 12 with hemophilia A and for use in surgical settings.

26 Feb 2016

UCSF, CipherHealth jointly launch customizable care-management platform

The University of California, San Francisco and healthcare technology firm CipherHealth LLC have launched a customizable care-management platform called View that aims to improve the quality of care for patients with complex health conditions.

25 Feb 2016

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Rigel Pharmaceuticals Inc. today announced that it has initiated a Phase 2 clinical trial to evaluate fostamatinib, its oral SYK inhibitor, as a potential treatment for autoimmune hemolytic anemia (AIHA).

25 Feb 2016

Study: Magnesium therapy can alleviate muscular symptoms in patients with Motor Neurone Disease

Around 5,000 Motor Neurone Disease (MND) sufferers across the UK could find relief to their muscular symptoms thanks to transdermal (through the skin) magnesium therapy, say health pioneers BetterYou.

From BetterYou Ltd 25 Feb 2016

Meds-in-Hand helps improve outcomes for pediatric patients with asthma

A new study demonstrates that pediatric patients with asthma who left the hospital with their prescription medications made fewer emergency department (ED) visits after they were discharged than if they were discharged still needing to go to a pharmacy to pick-up their medications.

25 Feb 2016

High-intensity exercise may promote permanent structural changes in the heart

There is growing evidence that high levels of intense exercise may be cardiotoxic and promote permanent structural changes in the heart, which can, in some individuals, predispose them to experience arrhythmias (abnormal heart rhythm).

25 Feb 2016

College psychology courses lack important information about disabilities

Psychology classes are among the most popular courses on college campuses today, but new research shows that many of them lack important information about the largest single minority group in the U.S. - people with disabilities.

24 Feb 2016

Food-based proteins can help address child malnutrition in developing countries

Contrary to popular belief among world relief workers, children in developing countries may not be eating enough protein, which could contribute to stunted growth, a Johns Hopkins-directed study suggests.

24 Feb 2016

Inadequate dietary intake of essential amino acids and nutrient choline linked to stunting

Worldwide, an estimated 25 percent of children under age 5 suffer from stunted growth and development. The most visible characteristic is short stature, but the effects of stunting are far more profound: The condition prevents children from reaching their cognitive potential; makes them more susceptible to illness and infection; and shortens their life spans.

24 Feb 2016

Current DRG-based cost recovery system appears problematic for patients with complex disorders

A new study by researchers from Charité - Universitätsmedizin Berlin compares the true cost of treating patients with chronic inflammatory bowel disease with costs recoverable under the current German DRG-based system.

24 Feb 2016

Chronic News and Research

Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

TTR protein causes autoimmune reaction in joints of juvenile idiopathic arthritis patients

Novartis announces FDA approval of Afinitor for progressive, nonfunctional neuroendocrine tumors of GI

Homeless adults have more geriatric conditions than those living in homes

Lilly announces CHMP positive opinion for ixekizumab for treatment of adults with plaque psoriasis

EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

New ways to monitor physical activity at workplace

Digital health: the future for medicine?

Protein p62 acts as molecular brake to keep inflammation in check, avoid collateral damage

New review suggests solutions that can help ease chronic pain in women

Baxalta seeks FDA approval for ADYNOVATE to treat children with hemophilia A and for use in surgical settings

UCSF, CipherHealth jointly launch customizable care-management platform

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Study: Magnesium therapy can alleviate muscular symptoms in patients with Motor Neurone Disease

Meds-in-Hand helps improve outcomes for pediatric patients with asthma

High-intensity exercise may promote permanent structural changes in the heart

College psychology courses lack important information about disabilities

Food-based proteins can help address child malnutrition in developing countries

Inadequate dietary intake of essential amino acids and nutrient choline linked to stunting

Current DRG-based cost recovery system appears problematic for patients with complex disorders

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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