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Diet and exercise have potential to improve chemotherapy effectiveness in pediatric cancer patients

Diet and exercise may improve treatment outcomes in pediatric cancer patients, according to a study at The University of Texas MD Anderson Children's Cancer Hospital.

21 Sep 2017

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Inspired by the Labyrinth of Greek mythology, a new chip etched with fluid channels sends blood samples through a hydrodynamic maze to separate out rare circulating cancer cells into a relatively clean stream for analysis. It is already in use in a breast cancer clinical trial.

21 Sep 2017

Researchers identify exosomes as missing link to insulin resistance in type 2 diabetes

Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now.

21 Sep 2017

Forgotten strands of DNA induce 'big bang' of immune cell development

Intricate human physiological features such as the immune system require exquisite formation and timing to develop properly. Genetic elements must be activated at just the right moment, across vast distances of genomic space.

21 Sep 2017

New discovery about high-risk Alzheimer’s gene suggests potential therapeutic target

Nearly a quarter century ago, a genetic variant known as ApoE4 was identified as a major risk factor for Alzheimer's disease- one that increases a person's chances of developing the neurodegenerative disease by up to 12 times.

21 Sep 2017

DNA discovery could help point towards causes of developmental condition in children

New insights into how our cells store and manage DNA during cell division could help point towards the causes of a rare developmental condition.

21 Sep 2017

Researchers assess self-monitoring of blood glucose behavior among diabetes patients in China

Researchers in China who assessed self-monitoring of blood glucose behavior among nearly 19,000 patients with type 2 diabetes treated with oral medications reported very low SMBG rates both before and after the patients began treatment with basal insulin, although the data showed an increase in mean SMBG frequency after 6 months and the percentage of patients who never monitored their blood glucose decreased.

21 Sep 2017

Scientists use genome editing to understand role of a gene key to human embryonic development

Researchers have used a genome-editing technique to elucidate the role of a gene that is key to human embryonic development.

21 Sep 2017

Researchers identify new genetic test to help predict cancer recurrence

Researchers have discovered a new genetic test which could help predict cancer recurrence - paving the way for more precise, personalized treatments.

21 Sep 2017

Study identifies slowly proliferating and highly invasive melanoma cells

A study conducted at The Wistar Institute has led to the identification of a slowly proliferating and highly invasive melanoma cell subpopulation, characterized by production of a protein associated with invasive behavior. The research was published in the journal Oncogene.

21 Sep 2017

JAX professor receives $5.4 million grant to study 'cognitive resilience' to Alzheimer's disease

A new five-year grant totaling $5,382,423 to Jackson Laboratory Assistant Professor Catherine Kaczorowski will fund research to explore why some people with a family history of Alzheimer's disease, and even brain changes associated with the disease, nevertheless manage to maintain their cognitive capabilities.

21 Sep 2017

Communication breakdowns between care facilities can pave way for drug-resistant infection

Communication breakdowns between care facilities can pave the way for outbreaks of infection, according to research on the spread of an extensively drug-resistant bacterium.

21 Sep 2017

MIT engineers design more effective synthetic mRNA delivery system

By delivering strands of genetic material known as messenger RNA into cells, researchers can induce the cells to produce any protein encoded by the mRNA. This technique holds great potential for administering vaccines or treating diseases such as cancer, but achieving efficient delivery of mRNA has proven challenging.

21 Sep 2017

Regeneration ability may lie with the body's innate immune system, study shows

The answer to regenerative medicine's most compelling question -- why some organisms can regenerate major body parts such as hearts and limbs while others, such as humans, cannot -- may lie with the body's innate immune system, according to a new study of heart regeneration in the axolotl, or Mexican salamander, an organism that takes the prize as nature's champion of regeneration.

21 Sep 2017

Study uncovers millions of previously unknown genes in human microbiome

A new study of the human microbiome- the trillions of microbial organisms that live on and within our bodies- has uncovered millions of previously unknown genes from microbial communities in the human gut, skin, mouth, and vaginal microbiome, allowing for new insights into the role these microbes play in human health and disease.

20 Sep 2017

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Researchers at the Spanish National Cancer Research Centre have discovered a genetic alteration that is directly involved in at least 10% of cases of one of the most common cancers in children, T-cell acute lymphoblastic leukemia.

20 Sep 2017

Study may provide insights into treating autism and other neuropsychiatric disorders

Alterations in a naturally occurring chemical in the brain called serotonin have been linked to a number of neuropsychiatric disorders including depression, anxiety, obsessive-compulsive disorder as well as autism spectrum disorder (ASD).

20 Sep 2017

Researchers receive $11.5 million program project grant to eliminate drug resistant malaria

Texas Biomedical Research Institute researchers, Dr. Tim Anderson and Dr. Ian Cheeseman, have partnered with researchers at the University of Notre Dame and the Center for Infectious Disease Research in Seattle to pursue studies in drug resistant malaria.

20 Sep 2017

Risk factors, symptoms, diagnosis and treatment of ovarian cancer

Ovarian cancer is the 9th most common cancer in women and although it only accounts for approximately 3 percent of cancers in women, it is responsible for the most deaths of any cancer involving the female reproductive tract.

20 Sep 2017

Discovery reveals new role for endoplasmic reticulum-associated degradation

The discovery of a puddle of mouse urine seems like a strange scientific "eureka" moment. However, for one team of researchers, that's exactly what led to a new discovery.

20 Sep 2017

Genetic News and Research

Diet and exercise have potential to improve chemotherapy effectiveness in pediatric cancer patients

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Researchers identify exosomes as missing link to insulin resistance in type 2 diabetes

Forgotten strands of DNA induce 'big bang' of immune cell development

New discovery about high-risk Alzheimer’s gene suggests potential therapeutic target

DNA discovery could help point towards causes of developmental condition in children

Researchers assess self-monitoring of blood glucose behavior among diabetes patients in China

Scientists use genome editing to understand role of a gene key to human embryonic development

Researchers identify new genetic test to help predict cancer recurrence

Study identifies slowly proliferating and highly invasive melanoma cells

JAX professor receives $5.4 million grant to study 'cognitive resilience' to Alzheimer's disease

Communication breakdowns between care facilities can pave way for drug-resistant infection

MIT engineers design more effective synthetic mRNA delivery system

Regeneration ability may lie with the body's innate immune system, study shows

Study uncovers millions of previously unknown genes in human microbiome

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Study may provide insights into treating autism and other neuropsychiatric disorders

Researchers receive $11.5 million program project grant to eliminate drug resistant malaria

Risk factors, symptoms, diagnosis and treatment of ovarian cancer

Discovery reveals new role for endoplasmic reticulum-associated degradation

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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