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Mitochondrial-proteasome-heme axis rewires T cell fate and weakens cancer therapy

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed.

18 Mar 2026

Study finds GLP-1 medicines cut fat while preserving muscle function

Researchers found that GLP-1 medicines caused weight loss mainly through fat reduction, with only modest decreases in absolute muscle mass and no disproportionate loss of muscle function. In mice, physical performance improved, while in a small 12-week human pilot trial, strength was preserved despite reduced thigh muscle size.

18 Mar 2026

Protein targeted by cancer drugs may help the body fight influenza

A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX).

18 Mar 2026

Muscle-repairing macrophages trigger heterotopic ossification in mice

We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ossificans progressiva (FOP), Mrep functions as a pathogenic cell that triggers heterotopic ossification.

18 Mar 2026

New approach tracks metabolic fingerprints of tuberculosis-infected human cells

Researchers from King's College London and the University of Surrey have developed a new technique to measure the content of individual human cells infected with bacteria that model tuberculosis – and it is already revealing biological changes that conventional analysis would miss.

18 Mar 2026

New nanoparticle therapy overcomes T cell exhaustion in solid tumors

Engineers at the University of Pennsylvania have developed a new type of lipid nanoparticle (LNP) that could one day serve as a universal immunotherapy for cancers that form solid tumors, including common variants such as cancers of the breast, liver and colon.

18 Mar 2026

New approach developed to visualize proteins at unprecedented scale and sensitivity

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions.

18 Mar 2026

Newly identified protein regulates lysosome positioning and cellular metabolism

Lysosomes are the control centers for the metabolism of cells and tissues, including the brain. They break down defective proteins and other macromolecules into their basic building blocks.

18 Mar 2026

Sartorius launches next-generation platform to boost efficiency in cell therapy production

The life science group Sartorius is launching an integrated system for the production and quality control (QC) of autologous cell therapies.

From Sartorius 18 Mar 2026

Scaffold-free muscle patches show promise for injury repair

Traumatic muscle injury can be associated with volumetric muscle loss (VML), often leading to permanent functional loss.

17 Mar 2026

Study finds common brain mechanism behind different anesthesia drugs

When patients undergo general anesthesia, doctors can choose among several drugs. Although each of these drugs acts on neurons in different ways, they all lead to the same result: a disruption of the brain's balance between stability and excitability, according to a new MIT study.

17 Mar 2026

Zebrafish reveal how new kidney units connect and function

MDI Bio Lab scientists discover how the fish solves a basic challenge in regenerative biology-insights in their newest publication in the journal Development could one day guide human repair.

17 Mar 2026

Study identifies brain pathway crucial for proper functioning of working memory

Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining information.

17 Mar 2026

Modified lipid nanoparticles boost mRNA vaccines while reducing side effects

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever and general malaise.

17 Mar 2026

AlphaFold Database expands with millions of predicted protein complexes

A new collaboration between EMBL's European Bioinformatics Institute (EMBL-EBI), Google DeepMind, NVIDIA, and Seoul National University has made millions of AI-predicted protein complex structures openly available through the AlphaFold Database.

17 Mar 2026

Reducing lung cell lipid production decreases metastatic tumor spread

Scientists from the VIB–KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, have discovered how cancer cells can exploit healthy lung cells to support metastatic tumor growth in the lungs.

17 Mar 2026

Lysosomal storage of drugs may influence cancer treatment outcomes

One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others.

17 Mar 2026

Study reveals new dual role of ezrin in osteosarcoma

Scientists at Georgetown University's Lombardi Comprehensive Cancer Center have uncovered a new dual function for a well-known cancer-related protein called ezrin.

17 Mar 2026

Implantable device boosts immune cells to fight cancer effectively

Immunotherapy has transformed cancer treatment by harnessing the body's own immune system to fight disease.

17 Mar 2026

Blocking fructose metabolism may improve brain tumor immunotherapy response

Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study published on March 17 in the Proceedings of the National Academy of Sciences.

17 Mar 2026