Immune Response News and Research

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Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Researchers developed a novel intranasal vaccine candidate for coronavirus disease 2019 (COVID-19).

14 Apr 2023

B cells use mechanical force to pull antigen molecules off other cells

Most cells evolve slowly, accumulating incremental changes that better suit their environments. Immune cells, because they must adapt rapidly to counter new threats, evolve much more quickly.

13 Apr 2023

The importance and challenges of developing mucosal SARS-COV-2 vaccines

In November 2022, the National Institute of Allergy and Infectious Diseases co-hosted a virtual workshop on the importance and challenges of developing mucosal vaccines for SARS-COV-2.

13 Apr 2023

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

The current COVID-19 vaccines are designed to trigger an antibody response to the SARS-CoV-2 spike protein, which is vulnerable to mutations that could make the vaccine less effective over time.

13 Apr 2023

Using an implantable nanofluidic device to tame pancreatic cancer

Houston Methodist nanomedicine researchers have found a way to tame pancreatic cancer - one of the most aggressive and difficult to treat cancers - by delivering immunotherapy directly into the tumor with a device that is smaller than a grain of rice.

13 Apr 2023

Women vaccinated for COVID-19 have higher risk for heavier menstrual flow

A new international study finds that women vaccinated for COVID-19 have a slightly higher risk for a heavier period after vaccination.

13 Apr 2023

Genomic study reveals Babesia duncani's pathogenicity and virulence

'Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between May and October by a tick.

13 Apr 2023

MHRA research evaluates two different approaches to cancer therapies

The report 'Antibody conjugates for targeted delivery of Toll-like receptor 9 agonist to the tumor tissue', published in the PLOS ONE journal, highlights MHRA research which showed that genetic engineering of antibodies used to activate and support the immune system against cancer leads to improvements in their reliability and effectiveness.

13 Apr 2023

New tool provides insight into the developmental history of certain immune cells

A new tool that can uncover the developmental history of certain immune cells is now freely available worldwide. The tool provides insights into the stages that immune cells go through in a healthy individual and how this can be impacted in disease.

13 Apr 2023

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Developing and testing new treatments or vaccines for humans almost always requires animal trials, but these experiments can sometimes take years to complete and can raise ethical concerns about the animals' treatment.

12 Apr 2023

A creative new approach to make vaccine against norovirus

Every year, norovirus causes hundreds of millions of cases of food poisoning - and the deaths of at least 50,000 children - yet there exists no real way to control it.

11 Apr 2023

Novel optical imaging approach provides four-dimensional view of cell secretions

Cell secretions like proteins, antibodies, and neurotransmitters play an essential role in immune response, metabolism, and communication between cells.

11 Apr 2023

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

In Brazil, a group of researchers supported by FAPESP created mutant forms of Salmonella to understand the mechanisms that favor colonization of the intestinal tract of chickens by these pathogenic bacteria and find better ways to combat the infection they cause.

11 Apr 2023

Using tiny bubbles to improve gene therapy

Beyond vaccines, mRNA offers immense potential to fight disease, but targeting the genetic material to specific diseased cells is challenging - requiring a new method.

11 Apr 2023

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Researchers found antibodies that neutralize all current SARS-CoV-2 variants.

11 Apr 2023

Immunotherapy response in patients with advanced melanoma depends on prior treatments

Research led by scientists at UCLA Jonsson Comprehensive Cancer Center found that responses to a type of immunotherapy called PD-1 checkpoint blockade in patients with advanced melanoma depended on whether or not they had previously received another immunotherapy – CTLA-4 blockade – as well as other factors.

10 Apr 2023

Study highlights the potential long-term neurological effects post-COVID-19

Researchers studied the presence of the SARS-CoV-2 spike protein in the skull-meninges-brain (SMB) axis.

10 Apr 2023

Air pollution lowers COVID-19 vaccine immune response

In a recent study published in the journal Environmental Health Perspectives, researchers performed a population-level cohort study in Catalonia, Spain, to evaluate the association between exposure to air pollution for a prolonged duration and coronavirus disease 2019 (COVID-19) vaccine-induced antibody response.

9 Apr 2023

Research finds SARS-CoV-2 Omicron variant to be more fatal than seasonal influenza

Adults hospitalized with the SARS-CoV-2 Omicron variant have a higher death rate than those hospitalized with seasonal influenza, even though Omicron is considered less virulent with lower case fatality rates than the delta and alpha strains, new research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April) suggests.

7 Apr 2023

Specific proteins in the blood may help predict which COVID-19 patients may become critically ill

Researchers at Washington University School of Medicine in St. Louis have identified specific proteins that may help predict which COVID-19 patients may need to be placed on ventilators to breathe and which are most likely to die of the virus.

6 Apr 2023

Immune Response News and Research

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

B cells use mechanical force to pull antigen molecules off other cells

The importance and challenges of developing mucosal SARS-COV-2 vaccines

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

Using an implantable nanofluidic device to tame pancreatic cancer

Women vaccinated for COVID-19 have higher risk for heavier menstrual flow

Genomic study reveals Babesia duncani's pathogenicity and virulence

MHRA research evaluates two different approaches to cancer therapies

New tool provides insight into the developmental history of certain immune cells

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

A creative new approach to make vaccine against norovirus

Novel optical imaging approach provides four-dimensional view of cell secretions

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

Using tiny bubbles to improve gene therapy

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Immunotherapy response in patients with advanced melanoma depends on prior treatments

Study highlights the potential long-term neurological effects post-COVID-19

Air pollution lowers COVID-19 vaccine immune response

Research finds SARS-CoV-2 Omicron variant to be more fatal than seasonal influenza

Specific proteins in the blood may help predict which COVID-19 patients may become critically ill

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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