Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

New understanding of the disease process involved in atherosclerosis

The progression of the artery-clogging disease atherosclerosis is linked to the inability of specialized bone marrow cells to continuously repair damage to the arterial lining, Duke University Medical Center researchers have demonstrated.

13 Nov 2005

Scientists identify molecular link between body fat and blood lipids

Scientists from Wageningen University in the Netherlands have discovered that a factor released from body fat, which they call Fasting-Induced Adipose Factor or FIAF, has a major impact on blood levels of HDL and triglycerides in mice.

10 Nov 2005

2 million American children at risk of diabetes

According to a new study, as many as 2 million children in the U.S. aged 12 to 19 have a prediabetic condition or prediabetes, that is often linked to obesity and physical inactivity.

8 Nov 2005

Diabetic black men have lower amounts of atherosclerosis than diabetic white men

In a surprising outcome, investigators at Wake Forest University Baptist Medical Center found that diabetic black men have dramatically lower amounts of atherosclerosis, or hardening of the arteries, than diabetic white men.

3 Nov 2005

HDLs provide human immunity to certain parasites

For years biomedical researchers have known that high density lipoproteins, commonly called HDLs or "good cholesterol," are responsible for protecting humans from certain parasites, but couldn't explain how.

30 Oct 2005

Women with defects in lipoprotein metabolism may actually be able to bear children without complications

A group of Belgian researchers has determined that a pregnant woman's ability to metabolize fats is determined not only by her genes but by her baby's genes as well.

30 Oct 2005

Ethnic differences in cardiovascular risk factors

Heredity plays a major role in determining the blood lipid profile and heart rate variability of blacks and whites, two major risk factors for coronary artery disease, researchers say.

16 Oct 2005

Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies

"There was no apparent safety concern for patients whose resultant LDL on intensive therapy was lower than current guidelines. There was a trend toward improved clinical outcomes in the lowest LDL groups," said Stephen D. Wiviott, M.D., from Brigham and Women's Hospital in Boston, Massachusetts.

11 Oct 2005

Cholesterol levels among older adults has declined significantly

The total cholesterol level among older adults has declined significantly, while there has been little change among younger adults, according to a study in the October 12 issue of JAMA: The Journal of the American Medical Association.

11 Oct 2005

Possible vaccine to protect newborns from fatal bacteria Group B Streptococcus

Microbiologists from the University of Bradford believe they may be closer to developing a vaccine that can protect newborn babies from being infected by the common and potentially fatal bacteria Group B Streptococcus.

5 Oct 2005

Benefits of statin therapy identified

The greater the reduction in LDL (lower-density lipoprotein) cholesterol achieved by statin therapy the greater the reduction in incidence of major coronary events, coronary revascularisation and stroke, concludes a meta-analysis published online today by The Lancet.

27 Sep 2005

Carbohydrate-based vaccine against cancer?

Couldn't we be immunized against cancer? This sounds like a dream, but is in fact a thoroughly realistic research goal. American researchers have now taken an important step forward in the development of a cancer vaccine.

29 Aug 2005

Researchers find drug targets for treating metabolic syndrome

Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition.

11 Aug 2005

Visceral obesity may be an important risk factor for insulin resistance syndrome in children

Waist circumference is associated with insulin resistance in children and may offer a simple way to identify children with risk factors for cardiovascular disease and type 2 diabetes, according to a study in the August issue of Archives of Pediatrics & Adolescent Medicine.

1 Aug 2005

Working class twins fare worse than their professional sibs on blood pressure, cholesterol and self-rated health

Nancy Krieger, professor of society, human development and health at the Harvard School of Public Health and colleagues, compared the health status, education levels and adult occupational class among women who were identical twins and who lived together through adolescence, to demonstrate that adult socioeconomic conditions affect adult health, above and beyond genetics and early life conditions.

26 Jul 2005

Maintaining a healthy weight in children may be one good way to keep a healthy blood lipid profile and a happy heart

A study of 400 high school age children with a variety of fitness and fatness levels showed that fatter youths had unfavorable lipid profiles, including higher levels of triglycerides and higher ratios of total cholesterol to the protective HDL cholesterol or high density lipoprotein.

21 Jul 2005

News we always wanted to hear - Chocolate does you good!

In the best news yet for chocolate lovers, a new study has apparently shown that dark chocolate can lower blood pressure.

19 Jul 2005

Genes play an overriding role in cholesterol response

Why does it seem like some people can eat all the ice cream they want without increasing their cholesterol or gaining much weight, while others with high cholesterol have to watch their diets like a hawk? Because no matter what their lifestyle, people's genes play an overriding role in their cholesterol response.

11 Jul 2005

First blood test to help predict a patient's risk for ischemic stroke

The U.S. Food and Drug Administration (FDA) has approved the first blood test designed to help predict a patient's risk for ischemic stroke, the most common type of stroke and one of the nation's leading causes of long-term disability affecting approximately 700,000 people per year.

19 Jun 2005

Teen-age boys with type 1 diabetes showed evidence of greater atherosclerosis

Youths with type 1 diabetes, especially boys, already show early signs of cardiovascular disease by their teen-age years, according to researchers from the Keck School of Medicine of the University of Southern California and Childrens Hospital Los Angeles.

13 Jun 2005