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Neurotransmitter responsible for brain arousal plays vital role in early sensory perceptions

Being aware of our surroundings is a fundamental aspect of our existence. But what in our biological makeup determines how we access and interpret the endless stream of information around us?

10 Jul 2018

Breakthrough finding may pave way for new COPD treatments

Permanent lung damage caused by chronic obstructive pulmonary disease starts much earlier than previously thought, even before patients are showing symptoms.

10 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

10 Jul 2018

Reducing length of antibiotic course decreases risk of drug resistance

Treatments using antibiotics should stop as soon as possible to prevent patients passing the "tipping point" of becoming resistant to their effects, new research has shown.

10 Jul 2018

New approach could greatly enhance people's long-term tolerance for transplants

Currently, people receiving organ transplants must take drugs to suppress the inflammatory immune response that leads to rejection. Even so, almost all recipients eventually lose their transplant.

10 Jul 2018

Researchers investigate how genetic data can be made accessible in medical practice

In a project funded by the Austrian Science Fund FWF, a research group from Vienna investigated how genetic data can be made accessible in medical practice in order to improve the safety and effectiveness of medication.

10 Jul 2018

Sartorius Stedim Biotech and Penn State partner to advance teaching, research in biotechnology

Sartorius Stedim Biotech and Penn State University have entered into a collaborative partnership to advance multidisciplinary teaching and research in biotechnology. This long-term relationship will support the education and preparation of the next generation of biotechnology leaders.

From Sartorius 10 Jul 2018

Researchers design artificial intelligence system for predicting drug combinations' side effects

Last month alone, 23 percent of Americans took two or more prescription drugs, according to one CDC estimate, and 39 percent over age 65 take five or more, a number that's increased three-fold in the last several decades.

10 Jul 2018

Multivitamin and mineral supplements do not prevent cardiovascular diseases

Taking multivitamin and mineral supplements does not prevent heart attacks, strokes or cardiovascular death, according to a new analysis of 18 studies published in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

10 Jul 2018

Can insurers use genetic testing results? A reader wants to know

This week, I answer questions from readers concerned about health insurance roadblocks in the face of a serious illness or medical crisis.

10 Jul 2018

Study identifies constellation of metabolites linked to ME/CFS

A study led by researchers at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health has identified a constellation of metabolites related to myalgic encephalomyelitis/chronic fatigue syndrome.

10 Jul 2018

CTI BioPharma announces Phase III results of PIXUVRI combined with rituximab in aggressive B-cell NHL patients

CTI BioPharma Corp. and Servier today announced that the pivotal Phase III study evaluating PIXUVRI® combined with rituximab in comparison to gemcitabine combined with rituximab in patients with aggressive B-cell non-Hodgkin lymphoma did not meet its primary endpoint of improvement of progression-free survival

9 Jul 2018

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Researchers from the Department of Cell Biology, Physiology and Immunology and the Institute for Biotechnology and Biomedicine of the Universitat Autònoma de Barcelona have unmasked the functioning of a protein involved in DNA repair, ATR, in the meiotic recombination process which takes place during the development of spermatocytes - sperm precursor cells- and how inhibiting this protein causes anomalies which block spermatogenesis.

9 Jul 2018

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

One of the lines of research of the UPV/EHU's Lipids & Liver group, which focusses on the mechanisms involved in the development and progression of non-alcoholic fatty liver disease, is achieving significant advances in a range of aspects; these include the identification of proteins that alter the metabolic pathways in the development and progression of liver disease, and even cancer, and the seeking of targets to enable the disease to be reversed.

9 Jul 2018

New technique paves way for safer medicines without side effects

A new technique for precisely targeting molecules within cells is paving the way for safer medicines that are free of side effects.

9 Jul 2018

State prisons fail to offer cure to 144,000 inmates with deadly hepatitis C

State prisons across the U.S. are failing to treat at least 144,000 inmates who have hepatitis C, a curable but potentially fatal liver disease, according to a recent survey and subsequent interviews of state corrections departments.

9 Jul 2018

Incarceration of parents during childhood impacts youth behavior

A new study published in Pediatrics found that young adults who had a parent incarcerated during their childhood are more likely to skip needed healthcare, smoke cigarettes, engage in risky sexual behaviors, and abuse alcohol, prescription and illicit drugs.

9 Jul 2018

New study reveals potential shortcomings of antibiotic susceptibility assays

To determine which antibiotics reliably treat which bacterial infections, diagnostic laboratories that focus on clinical microbiology test pathogens isolated from patients.

9 Jul 2018

Study uncovers how a sticky protein promotes activity of estrogen in breast cancer cells

New research uncovers how a sticky protein called fibronectin promotes the activity of estrogen in breast cancer cells.

9 Jul 2018

Drugs News and Research

Neurotransmitter responsible for brain arousal plays vital role in early sensory perceptions

Breakthrough finding may pave way for new COPD treatments

Researchers use genome editing to reduce cholesterol levels in animal model

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Reducing length of antibiotic course decreases risk of drug resistance

New approach could greatly enhance people's long-term tolerance for transplants

Researchers investigate how genetic data can be made accessible in medical practice

Sartorius Stedim Biotech and Penn State partner to advance teaching, research in biotechnology

Researchers design artificial intelligence system for predicting drug combinations' side effects

Multivitamin and mineral supplements do not prevent cardiovascular diseases

Can insurers use genetic testing results? A reader wants to know

Study identifies constellation of metabolites linked to ME/CFS

CTI BioPharma announces Phase III results of PIXUVRI combined with rituximab in aggressive B-cell NHL patients

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

New technique paves way for safer medicines without side effects

State prisons fail to offer cure to 144,000 inmates with deadly hepatitis C

Incarceration of parents during childhood impacts youth behavior

New study reveals potential shortcomings of antibiotic susceptibility assays

Study uncovers how a sticky protein promotes activity of estrogen in breast cancer cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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