Protein C News and Research

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'Protein mapping' approach reveals why metastatic melanoma patients do not respond to immunotherapy

Tel Aviv University and Sheba Medical Center researchers say they have discovered why more than half of patients with metastatic melanoma do not respond to immunotherapy cancer treatments.

10 Sep 2019

Fatty food changes the brain to affect homeostasis and metabolism

While we all know that eating fatty food pushes up our body weight, a new study now shows it also affects the way the brain keeps track of and corrects all metabolic irregularities in the body. Soon after tucking into a high-fat, high-carb meal – as soon as three days later – the hypothalamus shows inflammation.

10 Sep 2019

Enzyme in plants key to developing novel pharmaceuticals

Plants have many superpowers, such as manufacturing compounds to help repel pests, protecting themselves from environmental hazards, and providing a plethora of essential oils and other compounds that can heal a multitude of infections and other diseases.

9 Sep 2019

High-fat diets contribute to irregularities in hypothalamus region of the brain

Much research has pointed to how an unhealthy diet correlates to obesity, but has not explored how diet can bring about neurological changes in the brain.

9 Sep 2019

Message transfer between mammal neurons regulated by 'clamp'

A fundamental question in nerve biology brings to mind a race car at the starting line: The engine is revving, but the brake is on. The system is ready to go, but under tight control.

9 Sep 2019

Older hospitalized patients with cancer may have a high risk of malnutrition

Results from a new study indicate that older hospitalized patients with cancer may have a high risk of being malnourished and experiencing symptoms such as no appetite and nausea, according to findings published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

9 Sep 2019

Researchers find synergistic connection between two deadly blood-clotting diseases

Two rare but potentially deadly blood-clotting diseases, namely thrombotic thrombocytopenic purpura, or TTP, and hemolytic uremic syndrome, or HUS, show similar pathologies -- a multitude of painful blockages in small blood vessels that cause varying degrees of organ injury throughout the body. However, the two disorders have distinct biological mechanisms.

8 Sep 2019

Serotonin and anti-depressants can have a major effect on the gut's microbiota

A new study in mice led by UCLA biologists strongly suggests that serotonin and drugs that target serotonin, such as anti-depressants, can have a major effect on the gut's microbiota -- the 100 trillion or so bacteria and other microbes that live in the human body's intestines.

6 Sep 2019

Inhibitory inputs to neurons in the visual cortex are more diverse than previously thought

Neurons are complex, highly connected cells engaged with multiple networks throughout the brain, and they exhibit a wide range of activity.

6 Sep 2019

VUMC partners with Batavia to move promising Zika antibody therapy closer to the clinic

Researchers at Vanderbilt University Medical Center are partnering with the Dutch biopharmaceutical firm Batavia Biosciences and Nashville-based IDBiologics to bring to the clinic a highly potent Zika virus neutralizing antibody they isolated three years ago.

6 Sep 2019

How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Researchers receive $2.5 million NIH grant to study role of artemin in oral cancer pain

Researchers at New York University Oral Cancer Center were awarded a $2.5 million grant (R01CA228525) from the National Cancer Institute, part of the National Institutes of Health, to study the role of artemin in oral cancer pain and growth.

5 Sep 2019

Lundbeck chooses Discngine’s 3decision platform for handling complex protein-ligand 3D structure data

Discngine, a software company specialized in developing applications for life sciences research, today announces that Lundbeck has selected its proprietary 3decision collaborative platform to manage the pharma company’s structural knowledge related to protein and ligand 3D structures.

5 Sep 2019

Researchers discover a molecule that regulates tumor development in different types of cancers

Researchers from the Josep Carreras Leukemia Research Institute, discover that a non-coding region of the genome originates a key molecule for the proliferation of tumors in breast cancer and some types of sarcoma.

5 Sep 2019

New drug may enhance efficacy of chemotherapy in pancreatic cancer

One of the major obstacles in the treatment of pancreatic cancer is the 'defense wall' that is formed around the tumor.

5 Sep 2019

Scientists visualize protein tangles linked with dementia in patients’ brains after single head injury

Scientists have visualized for the first time protein 'tangles' associated with dementia in the brains of patients who have suffered a single head injury.

5 Sep 2019

Large-scale study maps the genetic underpinnings of early TB progression

While the vast majority of the 1.8 billion people infected with the TB bacterium never experience active disease, an estimated 5 to 15 percent do develop full-blown infections--roughly half of them within 18 months of exposure.

4 Sep 2019

Study aims to achieve earlier diagnosis of ATTR cardiac amyloidosis in minority populations

Researchers at Boston Medical Center and Boston University School of Medicine, in collaboration with Columbia University Irving Medical Center, are leading a national, multi-site study aimed to achieve earlier diagnosis of transthyretin cardiac amyloidosis.

4 Sep 2019

Scientists find receptor protein in the brain that promotes stress resilience

Scientists have discovered that a receptor on the surface of brain cells plays a key role in regulating how both animals and people respond to stress.

4 Sep 2019

Researchers develop new technique for rapid breakdown of cellular proteins

Cellular functions depend on the functionality of proteins, and these functions are disturbed in diseases. A core aim of cell biological research is to determine the functions of individual proteins and how their disturbances result in disease.

4 Sep 2019

Protein C News and Research

'Protein mapping' approach reveals why metastatic melanoma patients do not respond to immunotherapy

Fatty food changes the brain to affect homeostasis and metabolism

Enzyme in plants key to developing novel pharmaceuticals

High-fat diets contribute to irregularities in hypothalamus region of the brain

Message transfer between mammal neurons regulated by 'clamp'

Older hospitalized patients with cancer may have a high risk of malnutrition

Researchers find synergistic connection between two deadly blood-clotting diseases

Serotonin and anti-depressants can have a major effect on the gut's microbiota

Inhibitory inputs to neurons in the visual cortex are more diverse than previously thought

VUMC partners with Batavia to move promising Zika antibody therapy closer to the clinic

How tuberculosis progresses: genetic factors play a major role

Researchers receive $2.5 million NIH grant to study role of artemin in oral cancer pain

Lundbeck chooses Discngine’s 3decision platform for handling complex protein-ligand 3D structure data

Researchers discover a molecule that regulates tumor development in different types of cancers

New drug may enhance efficacy of chemotherapy in pancreatic cancer

Scientists visualize protein tangles linked with dementia in patients’ brains after single head injury

Large-scale study maps the genetic underpinnings of early TB progression

Study aims to achieve earlier diagnosis of ATTR cardiac amyloidosis in minority populations

Scientists find receptor protein in the brain that promotes stress resilience

Researchers develop new technique for rapid breakdown of cellular proteins

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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