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Researchers identify common genetic connection in lung conditions

An international research team led by members of the University of Colorado School of Medicine faculty has identified a genetic connection between rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis.

22 Oct 2018

Research offers new hope to men who received childhood cancer treatment

Researchers have discovered a way to grow human stem cells destined to become mature sperm in an effort to provide fertility options later in life to males who are diagnosed with cancer and undergo chemotherapy and radiation as children.

22 Oct 2018

New orthodontic bracket bonding adhesive protects tooth surfaces from decay

Researchers at Queen Mary University of London have produced a new orthodontic bracket bonding adhesive that protects the tooth surfaces around the brackets from decay. This decay is often referred to as white spot lesions which affects, according to a 2015 meta-analysis, nearly 70 percent of people fitted with orthodontic braces.

22 Oct 2018

Breathing through the nose improves memory consolidation

The way we breathe may affect how well our memories are consolidated (i.e. reinforced and stabilized). If we breathe through the nose rather than the mouth after trying to learn a set of smells, we remember them better, researchers at Karolinska Institutet in Sweden report in The Journal of Neuroscience.

22 Oct 2018

Study findings could set new standard of care for advanced anal cancer

A new approach to treating advanced anal cancer is safer and more effective than the most widely used current treatment, according to the first ever randomized clinical trial in this group of patients.

22 Oct 2018

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Genentech, a member of the Roche Group, today announced positive results from the Phase III IMpower130 study of Tecentriq (atezolizumab) plus chemotherapy (carboplatin and Abraxane® [albumin-bound paclitaxel; nab-paclitaxel]) for the initial (first-line) treatment of people with previously untreated metastatic non-squamous non-small cell lung cancer.

22 Oct 2018

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck, known as MSD outside the United States and Canada, today announced the first presentation of preliminary data from a Phase 1 clinical trial evaluating MK-1454, an investigational STING (stimulator of interferon genes) agonist, as monotherapy and in combination with KEYTRUDA (pembrolizumab), Merck's anti-PD-1 therapy, in patients with advanced solid tumors or lymphomas.

22 Oct 2018

Study suggests rising childhood obesity rates as cause for serious hip disease in adolescents

New research suggests that rising childhood obesity rates are causing more adolescents to develop a debilitating hip disease requiring urgent surgery.

22 Oct 2018

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck's anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ or CIS plus papillary disease (Cohort A).

22 Oct 2018

FDA approves update to Rituxan label to include information on treatment of rare forms of vasculitis

Genentech, a member of the Roche Group, announced today that the U.S. Food and Drug Administration has approved an update to the Rituxan® (rituximab) label to include information on follow up treatment of adult patients with Granulomatosis with Polyangiitis and Microscopic Polyangiitis who have achieved disease control with induction treatment.

22 Oct 2018

Vertex gets European CHMP positive opinion for KALYDECO to treat patients with cystic fibrosis

Vertex Pharmaceuticals (Europe) Limited today announces that the European Medicines Agency's Committee for Medicinal Products for Human Use adopted a positive opinion for KALYDECO (ivacaftor) to include the treatment of people with cystic fibrosis (CF) aged 12 to <24 months who have at least one of the following nine mutations in their cystic fibrosis transmembrane conductance regulator gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N or S549R.

22 Oct 2018

Study highlights existence of barriers to early clinical trial access for adolescents and young adults

Young cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congress in Munich, has highlighted the existence of barriers to the inclusion of 12 to 25-year-olds in both adult and pediatric early phase clinical trials, suggesting a need for more tailored approaches to give this patient population better access to therapeutic innovation.

22 Oct 2018

Resemblance to parents increases with offspring age in monkeys

Most of us would acknowledge that family members often resemble one another, particularly in the face. Indeed, humans are good at picking out pairs of close relatives amongst the faces of unfamiliar adults.

22 Oct 2018

Shorter course of trastuzumab could be an option for women with HER2+ early breast cancer

Women with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower risk of cardiac toxicity with a nine-week course of adjuvant trastuzumab compared to those treated for one year, according to a subgroup analysis of the Short-HER trial reported at ESMO 2018 Congress in Munich.

22 Oct 2018

Study reveals connection between two proteins known to be hyperactive in cancer

A team of researchers at Baylor College of Medicine and Texas Children's Hospital has revealed a connection between mTORC1 and Src, two proteins known to be hyperactive in cancer.

20 Oct 2018

Study reveals impact of Juul use on teenagers and young adults

Teens and young adults who use Juul brand e-cigarettes are failing to recognize the product's addictive potential, despite using it more often than their peers who smoke conventional cigarettes, according to a new study by researchers at the Stanford University School of Medicine.

19 Oct 2018

Scientists uncover key regulator of mTORC1 in cancer growth

Scientists have discovered that Src is needed for activation of mTORC1, a major regulator of cellular metabolism, growth and proliferation in cancer.

19 Oct 2018

Speech Pathology Australia raises awareness about Developmental Language Disorder

Speech Pathology Australia is driving a campaign in Australia to shed light on a hidden condition that affects on average two children in every classroom.

19 Oct 2018

Survey finds high prevalence of HTLV-1 infection among teens and adults in Gabon

A study published in PLOS Neglected Tropical Diseases, by Mirdad Kazanji, of the Centre International de Recherches Medicales de Franceville in Gabon, and the Institut Pasteur de la Guyane in French Guiana, suggests that 30 years after the first epidemiological survey of the seroprevalence of Human T-cell lymphotropic virus type 1 (HTLV-1) infections in Gabon, the country remains highly endemic, with a seroprevalence of 7.3%.

19 Oct 2018

NSF awards $5 million grant to help scientists magnify societal impact of research

When Humira came on the market, many found relief from symptoms of arthritis, plaque psoriasis, Crohn’s disease and ulcerative colitis.

19 Oct 2018

Children News and Research

Researchers identify common genetic connection in lung conditions

Research offers new hope to men who received childhood cancer treatment

New orthodontic bracket bonding adhesive protects tooth surfaces from decay

Breathing through the nose improves memory consolidation

Study findings could set new standard of care for advanced anal cancer

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Study suggests rising childhood obesity rates as cause for serious hip disease in adolescents

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

FDA approves update to Rituxan label to include information on treatment of rare forms of vasculitis

Vertex gets European CHMP positive opinion for KALYDECO to treat patients with cystic fibrosis

Study highlights existence of barriers to early clinical trial access for adolescents and young adults

Resemblance to parents increases with offspring age in monkeys

Shorter course of trastuzumab could be an option for women with HER2+ early breast cancer

Study reveals connection between two proteins known to be hyperactive in cancer

Study reveals impact of Juul use on teenagers and young adults

Scientists uncover key regulator of mTORC1 in cancer growth

Speech Pathology Australia raises awareness about Developmental Language Disorder

Survey finds high prevalence of HTLV-1 infection among teens and adults in Gabon

NSF awards $5 million grant to help scientists magnify societal impact of research

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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