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Research provides new target to help treat chemotherapy-induced diarrhea

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening.

27 Jun 2018

New approach needed to treat type 2 diabetes in youth

A major study has found that medicines used to treat diabetes in adults are not effective on youth. The researchers say the finding is disturbing because type 2 diabetes among youth is a growing problem.

27 Jun 2018

Researchers develop new approach for studying Cryptosporidium in healthy human tissues

Washington State University researchers have developed a new approach for studying Cryptosporidium, a waterborne gastrointestinal parasite now recognized as one of the leading causes of potentially life-threatening diarrheal disease in young children worldwide.

26 Jun 2018

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy.

26 Jun 2018

Researchers examine new influenza drug's mode of action in detail

The new influenza drug Xofluza, developed by the Japanese pharmaceutical company Shionogi, was approved for clinical use in Japan in February 2018.

26 Jun 2018

Combating cardiac complications caused by cancer treatment

Amie Goins has completed eight 5K runs in 2018. An impressive feat for a 46-year-old mother with a full-time job and two teenage sons to care for – downright astounding for a woman who was diagnosed with stage 2 breast cancer two days before Christmas last year. She's conquered months of treatment and difficult side effects while continuing to lace up.

26 Jun 2018

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells-- known as the PI3 kinase (PI3K) pathway--but efforts to develop therapies targeting this pathway have met with little success after hundreds of mostly failed clinical trials. And researchers still don't understand why.

26 Jun 2018

Antidepressant use in people with COPD linked to increased risk of death and hospitalization

Antidepressant use in people with chronic obstructive pulmonary disease is associated with a 20 percent increase in likelihood of death and a 15 percent increase in likelihood of hospitalization due to related symptoms, finds a new study led by researchers at St. Michael's Hospital.

26 Jun 2018

Thinking about an association health plan? Read the fine print

If you own a restaurant, plumbing company or other small business, you may be intrigued by the expected expansion of association health plans under a new rule that got a stamp of approval from the Trump administration last week.

26 Jun 2018

Scientists discover new kind of small-cell lung cancer

Researchers have discovered a new kind of small-cell lung cancer. The discovery paves the way for developing personalized medicine approaches to target this previously unnoticed form of the disease.

26 Jun 2018

Researchers identify novel mutation in amyloid diseases

Researchers have identified a one-of-a kind mutation in the DNA of a patient who died of transthyretin (TTR) amyloidosis, a progressive condition characterized by the buildup of abnormal deposits of a misfolded protein called amyloid in the body's organs and tissues.

26 Jun 2018

Study suggests new approach for treating alcohol use disorder

Activation of a receptor with no known function in the brain reduces excessive alcohol use and the pain of withdrawal, according to preclinical research in male rats. The study, published in eNeuro, suggests a new approach towards the treatment of alcohol use disorder.

26 Jun 2018

Canadian researchers uncover new molecular mechanism to stop proliferation of cancer cells

Canadian researchers have discovered a new and direct molecular mechanism to stop cancer cells from proliferating. In the prestigious journal Nature Cell Biology, scientists from Université de Montréal show that a disruption of a fine balance in the composition of ribosomes (huge molecules that translate the genetic code into proteins) results in a shutdown of cancer cell proliferation, triggering a process called senescence.

26 Jun 2018

FDA approves new marijuana-based drug to treat rare and severe forms of epilepsy

The U.S. Food and Drug Administration today approved Epidiolex (cannabidiol) oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, in patients two years of age and older.

25 Jun 2018

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

Scientists have used CRISPR-Cas9 gene editing to lessen some autism symptoms in mice with a form of fragile X syndrome, the most common known single-gene cause of autism spectrum disorder.

25 Jun 2018

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Researchers work on new treatment that could improve lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University are working on a treatment that holds great promise for improving the lives of cystic fibrosis patients.

25 Jun 2018

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy released a study investigating the use of combination checkpoint immunotherapy in the treatment of a lethal form of advanced prostate cancer.

25 Jun 2018

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Cedars-Sinai has launched an initiative to accelerate the development of novel drugs, devices and therapies aimed at improving treatments for patients with gastrointestinal and metabolic diseases.

25 Jun 2018

Drugs News and Research

Research provides new target to help treat chemotherapy-induced diarrhea

New approach needed to treat type 2 diabetes in youth

Researchers develop new approach for studying Cryptosporidium in healthy human tissues

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

Researchers examine new influenza drug's mode of action in detail

Combating cardiac complications caused by cancer treatment

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

Antidepressant use in people with COPD linked to increased risk of death and hospitalization

Thinking about an association health plan? Read the fine print

Scientists discover new kind of small-cell lung cancer

Researchers identify novel mutation in amyloid diseases

Study suggests new approach for treating alcohol use disorder

Canadian researchers uncover new molecular mechanism to stop proliferation of cancer cells

FDA approves new marijuana-based drug to treat rare and severe forms of epilepsy

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

Researchers discover immune profile for effective cancer immunotherapy

Researchers work on new treatment that could improve lives of cystic fibrosis patients

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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