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Researchers receive grant to evaluate efficacy of tobacco cessation methods

Researchers at The University of Kansas Cancer Center have received a five-year National Institutes of Health R0-1 grant to compare and evaluate the efficacy of optimized versus non-optimized tobacco cessation approaches for African American smokers.

27 Jun 2018

Researchers discover immune cells that create and sustain chronic inflammatory bowel disease

In preclinical experiments, Laurie Harrington, Ph.D., and colleagues at the University of Alabama at Birmingham have discovered a subset of immune cells that create and sustain chronic inflammatory bowel disease.

27 Jun 2018

New avenue for cancer treatment opens when one drug fails

A new class of cancer drugs – called CDK4/6 inhibitors -- recently approved to treat breast cancer can stunt the cancer's growth and replication.

27 Jun 2018

UPMC and Pitt announce launch of advanced genome sequencing center

UPMC and the University of Pittsburgh today announced the launch of an advanced genome sequencing center to support clinical diagnostics and research initiatives in precision medicine and immunotherapy.

27 Jun 2018

Trauma experienced by separated immigrant children will have future implications, says expert

The damage has been done. More than 2,000 children remain separated from their parents or guardians in detention centers with no plan to be reunited, despite President Trump's new executive order.

27 Jun 2018

Polio virus could help brain cancer patients

According to researchers genetically altered poliovirus strains could help some patients of brain cancer. A team of researchers from Duke University in Durham, North Carolina, used modified polio virus strains in small groups of patients who had glioblastoma – a particularly deadly form of brain cancer. In these patients standard treatments have failed say the researchers and this novel therapy could help.

27 Jun 2018

Study shows benefits, safety of long-lasting radionuclide therapy for patients with advanced NETs

A first-in-human study presented at the 2018 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging demonstrates the benefits and safety of a new, long-lasting type of radionuclide therapy for patients with advanced, metastatic neuroendocrine tumors.

26 Jun 2018

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy.

26 Jun 2018

Phase 1 clinical trial of poliovirus therapy shows long-term survival benefit for recurrent glioblastoma

A genetically modified poliovirus therapy developed at Duke Cancer Institute shows significantly improved long-term survival for patients with recurrent glioblastoma, with a three-year survival rate of 21 percent in a phase 1 clinical trial.

26 Jun 2018

Are wearable defibrillators a suitable alternative to surgically implanted devices?

Wearable defibrillators may be a safe and effective alternative to surgically implanted devices among children with ventricular arrythmias that increase the risk of sudden cardiac death, according to a new study.

26 Jun 2018

Combating cardiac complications caused by cancer treatment

Amie Goins has completed eight 5K runs in 2018. An impressive feat for a 46-year-old mother with a full-time job and two teenage sons to care for – downright astounding for a woman who was diagnosed with stage 2 breast cancer two days before Christmas last year. She's conquered months of treatment and difficult side effects while continuing to lace up.

26 Jun 2018

Novel theranostic agent designed for precise tumor diagnosis and therapy

A novel, intelligent theranostic agent for precise tumor diagnosis and therapy has been developed that remains as small molecules while circulating in the bloodstream, can then self-assemble into larger nanostructures in the tumor, and be activated by the tumor microenvironment for therapy guided by photoacoustic imaging.

26 Jun 2018

Serotonin enhances speed of learning, study finds

An international team from the Champalimaud Centre for the Unknown, in Portugal, and the University College London, in the UK, has uncovered a previously unknown effect of serotonin on learning.

26 Jun 2018

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells-- known as the PI3 kinase (PI3K) pathway--but efforts to develop therapies targeting this pathway have met with little success after hundreds of mostly failed clinical trials. And researchers still don't understand why.

26 Jun 2018

New molecular imaging method could help effectively tackle brain conditions

A new molecular imaging method can monitor the success of gene therapy in all areas of the brain, potentially allowing physicians to more effectively tackle brain conditions such as Parkinson's disease, Alzheimer's disease and multiple sclerosis.

26 Jun 2018

UVA research shows true nature of immune cells blamed in Alzheimer's

Immune cells commonly blamed in Alzheimer's and other neurodegenerative diseases are actually precision cleaning machines protecting the central nervous system, new research from the University of Virginia School of Medicine shows.

26 Jun 2018

Study reveals new way to inhibit capillary leakage in sepsis

Leakage from the blood capillaries is a key mechanism leading to septic shock and multiorgan failure, which affect millions of patients annually worldwide. However, there is no effective way to inhibit the vessel leakiness. A new study by scientists at the University of Helsinki and Wihuri Research Institute demonstrates that vascular leakage can be inhibited by targeting vascular integrins.

25 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Researchers work on new treatment that could improve lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University are working on a treatment that holds great promise for improving the lives of cystic fibrosis patients.

25 Jun 2018

Therapy News and Research

Researchers receive grant to evaluate efficacy of tobacco cessation methods

Researchers discover immune cells that create and sustain chronic inflammatory bowel disease

New avenue for cancer treatment opens when one drug fails

UPMC and Pitt announce launch of advanced genome sequencing center

Trauma experienced by separated immigrant children will have future implications, says expert

Polio virus could help brain cancer patients

Study shows benefits, safety of long-lasting radionuclide therapy for patients with advanced NETs

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

Phase 1 clinical trial of poliovirus therapy shows long-term survival benefit for recurrent glioblastoma

Are wearable defibrillators a suitable alternative to surgically implanted devices?

Combating cardiac complications caused by cancer treatment

Novel theranostic agent designed for precise tumor diagnosis and therapy

Serotonin enhances speed of learning, study finds

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

New molecular imaging method could help effectively tackle brain conditions

UVA research shows true nature of immune cells blamed in Alzheimer's

Study reveals new way to inhibit capillary leakage in sepsis

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

Researchers discover immune profile for effective cancer immunotherapy

Researchers work on new treatment that could improve lives of cystic fibrosis patients

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