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Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

A team of researchers at Lund University in Sweden has developed a fluorescent variant of a molecule that inhibits cancer stem cells.

25 Jun 2018

Blocking viral-host interaction slows down flu virus replication, study shows

Influenza A (flu A) hijacks host proteins for viral RNA splicing and blocking these interactions caused replication of the virus to slow, according to new research published in Nature Communications by Kristin W. Lynch, PhD, chair of the department of Biochemistry and Biophysics in the Perelman School of Medicine at the University of Pennsylvania, and doctoral student Matthew Thompson.

25 Jun 2018

Studying The Effects of Microgravity on Muscle Mass

Studying the effects of gravity on muscle cells can give us an insight into muscle wastage diseases, and potentially guide the development of new therapies. Professor Louis Yuge discusses his research and the cellular changes that occur in response to microgravity.

25 Jun 2018

Scientists discover secret to success of antiviral gene

It's been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying.

25 Jun 2018

Novel approach to visualize how platelets are formed in body

Platelets are uniquely mammalian cells, and are the small cells of the blood that are critical for us to stop bleeding when we cut ourselves.

25 Jun 2018

Unique patch could revolutionize treatment of painful recurring ulcers

A plaster which sticks to the inside of your mouth is revolutionising the treatment of painful recurring ulcers.

25 Jun 2018

Researchers develop low-cost plastic sensors to monitor wide range of health conditions

An international team of researchers have developed a low-cost sensor made from semiconducting plastic that can be used to diagnose or monitor a wide range of health conditions, such as surgical complications or neurodegenerative diseases.

22 Jun 2018

FDA grants marketing authorization for use of two catheter-based devices in hemodialysis patients

Today, the U.S. Food and Drug Administration permitted marketing of two catheter-based devices designed to create a connection to veins and arteries in patients with chronic kidney disease who need hemodialysis.

22 Jun 2018

Research consortium wins £2.9 million to help tackle antibacterial resistance in Thailand

Antimicrobial resistance and specifically antibacterial resistance is a growing threat to human health and economic development across the globe. In Thailand, ABR was estimated to cause 38,000 deaths. The predicted economic loss on the country was 1.2 billion USD in 2010

22 Jun 2018

Overdose risk increases five-fold with concurrent opioid and benzodiazepine use

In the first 90 days of concurrent opioid and benzodiazepine use, the risk of opioid-related overdose increases five-fold compared to opioid-only use among Medicare recipients, according to a new study from the University of Pittsburgh School of Pharmacy, published today in JAMA Network Open

22 Jun 2018

Study highlights inadequate effort of health care insurers to combat opioid epidemic

Health care insurers including Medicare, Medicaid and major private insurers have not done enough to combat the opioid epidemic, suggests a study led by researchers at Johns Hopkins Bloomberg School of Public Health.

22 Jun 2018

Study suggests proteinuria lowering as important target in managing pediatric CKD

In a study of children with chronic kidney disease, blood pressure medications reduced protein excretion in the urine, which was linked with a lower risk of disease progression.

22 Jun 2018

Researchers discover drug compound that inhibits movement of cancer cells

Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body.

22 Jun 2018

Administering nitric oxide gas after heart surgery may decrease risk of kidney problems

Administration of nitric oxide gas during and for 24 hours following heart surgery decreased the risk of patients developing acute and chronic kidney problems, a randomized, controlled trial conducted in China found.

22 Jun 2018

New review outlines current state of sex-sensitive issues linked to heart failure drugs

Heart failure is almost as common in women as men, but its characteristics vary by sex.

22 Jun 2018

Scientists develop new device to test cancer drug combinations quickly and cheaply

Combinations of cancer drugs can be quickly and cheaply tested on tumor cells using a novel device developed by EMBL scientists

22 Jun 2018

Minakem's new high-class production facility extends capacity to develop and manufacture HPAPI compounds

Minakem, the CDMO division of Minafin, specialized in custom development and manufacturing of building blocks, GMP intermediates and Active Pharmaceutical Ingredients, today announces it is in the final qualification run to open a new closed-controlled environment high containment production facility in August.

22 Jun 2018

Doling out pain pills post-surgery: An ingrown toenail not the same as a bypass

What's the right painkiller prescription to send home with a patient after gallbladder surgery or a cesarean section?

22 Jun 2018

Study provides clues to how cancer cells develop resistance to chemotherapies

About half of all drugs, ranging from morphine to penicillin, come from compounds that are from - or have been derived from - nature. This includes many cancer drugs, which are toxic enough to kill cancer cells.

22 Jun 2018

Drugs News and Research

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

Blocking viral-host interaction slows down flu virus replication, study shows

Studying The Effects of Microgravity on Muscle Mass

Scientists discover secret to success of antiviral gene

Novel approach to visualize how platelets are formed in body

Unique patch could revolutionize treatment of painful recurring ulcers

Researchers develop low-cost plastic sensors to monitor wide range of health conditions

FDA grants marketing authorization for use of two catheter-based devices in hemodialysis patients

Research consortium wins £2.9 million to help tackle antibacterial resistance in Thailand

Overdose risk increases five-fold with concurrent opioid and benzodiazepine use

Study highlights inadequate effort of health care insurers to combat opioid epidemic

Study suggests proteinuria lowering as important target in managing pediatric CKD

Researchers discover drug compound that inhibits movement of cancer cells

Administering nitric oxide gas after heart surgery may decrease risk of kidney problems

New review outlines current state of sex-sensitive issues linked to heart failure drugs

Scientists develop new device to test cancer drug combinations quickly and cheaply

Minakem's new high-class production facility extends capacity to develop and manufacture HPAPI compounds

Doling out pain pills post-surgery: An ingrown toenail not the same as a bypass

Study provides clues to how cancer cells develop resistance to chemotherapies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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