Cell Death News and Research

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Award to help advance development of diagnostic test for necrotizing enterocolitis

The Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health has awarded Chosen Diagnostics Inc, a spin-out company, a $299,641 Phase I Small Business Technology Transfer award.

9 Dec 2019

Adding venetoclax to transplant conditioning regimen shows promise in patients with myeloid cancers

For patients with high-risk myeloid cancers undergoing a donor stem cell transplant, adding the targeted drug venetoclax to a reduced-intensity drug regimen prior to transplant is safe and does not impair the ability of the donor cells to take root in recipients' bodies, a study led by Dana-Farber Cancer Institute researchers suggests.

8 Dec 2019

Multiplexed C dots track different cancer targets to improve treatment

For more than a decade, researchers have used glowing nanoparticles called Cornell dots, or C dots, to illuminate cancer cells, target tumors and even induce cell death.

6 Dec 2019

NeutroCure project aims to cure inflammatory disease with neutrophils

Curing disease with neutrophils; this is the goal of the NeutroCure project. How will that work? "Neutrophils have a yin yang character," explained Andrés Hidalgo, whose team at the Centro Nacional de Investigaciones Cardiovasculares is one of six member groups participating in this project coordinated by Andriy Mokhir Friedrich from Alexander University, Germany.

5 Dec 2019

Scientists identify how damaged DNA molecules are repaired inside the human genome

A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its health and how it responds to diseases that stem from impaired DNA.

5 Dec 2019

Scientists create artificial neurons that help cure chronic diseases

Artificial brain cells could now be implanted in the brain to repair the damage caused by chronic diseases, such as Alzheimer’s disease and other neurodegenerative conditions, thanks to a team of scientists who created bionic neurons that work like the real thing.

4 Dec 2019

New discovery may bring scientists a step closer to developing hearing loss treatments

A new discovery from a team led by Massachusetts Eye and Ear researchers may bring scientists a step closer to developing treatments that regrow the lost cells that cause hearing loss.

4 Dec 2019

Scientist earns prestigious award for research into cell suicide

Apoptosis is a form of “cell suicide”, where a cell self-terminates, ideally as planned or programmed, enabling multi-cellular organisms to continue to live, develop and thrive.

4 Dec 2019

Failure in proteasome transportation system may cause neurodegenerative diseases

All neurodegenerative diseases have a common thread: the appearance of protein clumps in the brain such as amyloid-beta plaques in Alzheimer's disease and alpha synuclein aggregates in Parkinson's.

3 Dec 2019

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Gene expression profiling and other analyses conducted by Rutgers Cancer Institute of New Jersey researchers and colleagues examining drug resistance to a common antibody therapy for non-Hodgkin lymphoma have identified calcium signaling as a novel and exploitable target in overcoming this treatment obstacle.

3 Dec 2019

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease.

3 Dec 2019

Blood proteins could help provide a comprehensive 'liquid health check' in future

Proteins in our blood could in future help provide a comprehensive 'liquid health check', assessing our health and predicting the likelihood that we will we will develop a range of diseases, according to research published today in Nature Medicine.

2 Dec 2019

Small molecule can induce self-destruction of pancreatic cancer cells, study finds

Pancreatic cancer is resistant to all current treatments. Patients have extremely poor chances of surviving for five years after being diagnosed.

2 Dec 2019

“Liquid health check” could predict disease risk in the future

Measuring proteins in the blood could serve as a “liquid health check” that could predict people’s risk of developing diseases.

2 Dec 2019

Research findings provide novel therapeutic space to induce scarless regenerative healing

Abnormal scarring is a serious threat resulting in non-healing chronic wounds or fibrosis. Scars form when fibroblasts, a type of cell of connective tissue, reach wounded skin and deposit plugs of extracellular matrix.

27 Nov 2019

Over €12 million funding to advance autophagy research

Four years ago, Collaborative Research Centre (CRC) 1177 on selective autophagy was established under the leadership of Goethe University - now the German Research Foundation has given the green light for its further funding.

27 Nov 2019

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

While estrogen receptor - + breast cancers express high levels of three anti-apoptotic Bcl-2 family members, pharmacological inhibition of Bcl-2 and/or Bcl-xL fails to induce cell death in ER + breast cancer cell lines, due to rapid and robust Mcl-1 upregulation.

26 Nov 2019

Splicing factor enhances ability of triple negative breast cancers to grow and metastasize

If your DNA is a cookbook, a single gene is a recipe. But it's a flexible recipe that if edited one way can make a pie; edited another way can make a cake. And that difference can mean cancer, as a team of researchers who looked at those gene editors writes in the 26 November issue of Cell Reports.

26 Nov 2019

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows.

26 Nov 2019

New method for correcting hypoxic conditions of the central nervous system

Hypoxia is a key factor that accompanies most brain pathologies, including ischemia and neurodegenerative diseases.

26 Nov 2019

Cell Death News and Research

Award to help advance development of diagnostic test for necrotizing enterocolitis

Adding venetoclax to transplant conditioning regimen shows promise in patients with myeloid cancers

Multiplexed C dots track different cancer targets to improve treatment

NeutroCure project aims to cure inflammatory disease with neutrophils

Scientists identify how damaged DNA molecules are repaired inside the human genome

Scientists create artificial neurons that help cure chronic diseases

New discovery may bring scientists a step closer to developing hearing loss treatments

Scientist earns prestigious award for research into cell suicide

Failure in proteasome transportation system may cause neurodegenerative diseases

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Blood proteins could help provide a comprehensive 'liquid health check' in future

Small molecule can induce self-destruction of pancreatic cancer cells, study finds

“Liquid health check” could predict disease risk in the future

Research findings provide novel therapeutic space to induce scarless regenerative healing

Over €12 million funding to advance autophagy research

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

Splicing factor enhances ability of triple negative breast cancers to grow and metastasize

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

New method for correcting hypoxic conditions of the central nervous system

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics