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Scientists develop new model to predict a patient's risk for adverse events after hospital discharge

Historically, hospital patients have been at a high risk for adverse effects after they are discharged, according to the Institute of Medicine.

8 Jun 2018

International experts agree on need for human-relevant research to improve drug discovery

The average pre-approval cost of research and development for a successful drug is estimated to be US$2.6 billion and the number of new drugs approved per billion US dollars spent has halved roughly every 9 years since 1950.

8 Jun 2018

Synthetic cannabis use may increase risk of heart attack and stroke

The warning follows their treatment of a 25 year old prison inmate who had no family history of heart disease or traditional cardiovascular risk factors, and who was left with a permanent disability.

8 Jun 2018

Persistent substance use associated with higher risk of CKD progression and early death

In a study of patients with chronic kidney disease, persistent substance use - especially of hard illicit drugs - was linked with higher risks of CKD progression and early death. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

8 Jun 2018

Researchers discover new therapy combination that may help treat ovarian cancer

Researchers at The University of Kansas Cancer Center have discovered a therapy combination that may be helpful in the treatment of certain types of ovarian cancer.

8 Jun 2018

Brits cautioned against taking certain medicines abroad

The UK's Foreign Office has issued a statement warning Brits against carrying certain medications with them on holidays abroad.

7 Jun 2018

Kate Spade’s death ignites concern about rising suicide rate

Fashion designer Kate Spade's death Tuesday has reminded Americans of the enormous toll of suicide, a growing problem that claims nearly 45,000 lives a year.

7 Jun 2018

Research project aims to study opioid prescriptions after cesarean delivery and hysterectomy

Each year, approximately 1.8 million women will have a cesarean delivery or hysterectomy. While opioids are the mainstay treatment for acute pain after these surgeries, most women use only a fraction of the opioids prescribed and do not properly dispose of unused drugs

7 Jun 2018

Researchers develop model that predicts changes in BUP exposure during pregnancy

Buprenorphine (BUP) is approved for the treatment of opioid addiction. The current dosing regimen of BUP in pregnant women is based on recommendations designed for non-pregnant adults, but physiological changes during pregnancy may alter BUP exposure and efficacy.

7 Jun 2018

AFA awards grant to Stony Brook Medicine to improve drug development for Alzheimer's disease

The Alzheimer's Foundation of America is awarding $206,184 over the next three years to Stony Brook Medicine to support an innovative Positron Emission Tomography imaging research project that will compare neurons from healthy controls and those with Alzheimer's disease in an effort to improve drug development.

7 Jun 2018

Study finds high insurance denial rates for life-saving hepatitis C drugs in the U.S.

The number of insurance denials for life-saving hepatitis C drugs among patients with both private and public insurers remains high across the United States, researchers from the Perelman School of Medicine at the University of Pennsylvania reported in a new study published in the journal Open Forum Infectious Diseases.

7 Jun 2018

With the rise of legal weed, drug education moves from ‘don’t’ to ‘delay’

California legalized marijuana in 2016, and this past New Year’s Eve eager customers lined up in the darkness outside medical marijuana dispensaries across the state, ready to start shopping at the stroke of midnight.

7 Jun 2018

Two-drug combination provides more reliable, effective care for women suffering miscarriage

A combination of the drugs mifepristone and misoprostol can help bring closure to some women and their families suffering from miscarriage, and reduces the need for surgical intervention to complete the painful miscarriage process.

7 Jun 2018

UCLA researchers have blueprint of telomerase that plays major role in cancer, aging

Cancer, aging-related diseases and other illnesses are closely tied to an important enzyme called "telomerase." UCLA researchers report in the journal Cell the deepest scientific understanding yet of this once-mysterious enzyme, whose catalytic core -- where most of its activity occurs -- can now be seen in near atomic resolution.

7 Jun 2018

New approach to kill specific bacteria could be alternative to antibiotics

A new approach to killing C. difficile that silences key bacterial genes while sparing other bacteria may provide a new way to treat the most common hospital-acquired bacterial infection in the United States, according to researchers.

7 Jun 2018

Researchers’ attempt to combine immunotherapy drugs have turned out to be failure

A class of immunotherapy drugs called checkpoint inhibitors has shown great promise against cancer in some patients.

7 Jun 2018

FDA files complaint against company marketing unapproved hand sanitizers

The U.S. Food and Drug Administration today filed a complaint against Innovative BioDefense, Inc. of Lake Forest, California, and Colette Cozean, the company's president and chief executive officer, to prohibit them from selling Zylast topical antiseptics with claims that they are effective against infection by pathogens such as norovirus, rotavirus, flu virus, Methicillin-Resistant Staphylococcus Aureus, and Ebola.

7 Jun 2018

International 'A' team unveils new glioblastoma atlas

It takes an "A" team to make headway against glioblastoma, a highly aggressive type of brain cancer. Glioblastoma is the most common type of malignant brain tumor in adults. In addition to the caliber of the researchers involved, in this case "A" also stands for atlas.

6 Jun 2018

Overload of zinc in muscles leads to cachexia in cancer patients

It's estimated that nearly one-third of all cancer deaths are caused not by the cancer itself but by cachexia - a debilitating muscle-wasting syndrome that affects an estimated 80 percent of advanced cancer patients. Cachexia is linked to reduced tolerance for cancer therapy, poor quality of life, and accelerated death, but there are no effective treatments and its cause is still largely unknown.

6 Jun 2018

Study findings may lead to new approaches for treating inflammatory diseases

In the body, the immune system often begins its response to various attackers in the same way: the body activates immune cells, so-called phagocytes, which migrate to sites of inflammation caused by, for example, foreign pathogens or damaged tissue.

6 Jun 2018

Drugs News and Research

Scientists develop new model to predict a patient's risk for adverse events after hospital discharge

International experts agree on need for human-relevant research to improve drug discovery

Synthetic cannabis use may increase risk of heart attack and stroke

Persistent substance use associated with higher risk of CKD progression and early death

Researchers discover new therapy combination that may help treat ovarian cancer

Brits cautioned against taking certain medicines abroad

Kate Spade’s death ignites concern about rising suicide rate

Research project aims to study opioid prescriptions after cesarean delivery and hysterectomy

Researchers develop model that predicts changes in BUP exposure during pregnancy

AFA awards grant to Stony Brook Medicine to improve drug development for Alzheimer's disease

Study finds high insurance denial rates for life-saving hepatitis C drugs in the U.S.

With the rise of legal weed, drug education moves from ‘don’t’ to ‘delay’

Two-drug combination provides more reliable, effective care for women suffering miscarriage

UCLA researchers have blueprint of telomerase that plays major role in cancer, aging

New approach to kill specific bacteria could be alternative to antibiotics

Researchers’ attempt to combine immunotherapy drugs have turned out to be failure

FDA files complaint against company marketing unapproved hand sanitizers

International 'A' team unveils new glioblastoma atlas

Overload of zinc in muscles leads to cachexia in cancer patients

Study findings may lead to new approaches for treating inflammatory diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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