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Klotho hormone can protect kidney from renal fibrosis

A natural hormone known to inhibit aging can also protect kidneys against renal fibrosis, UT Southwestern Medical Center researchers have demonstrated.

15 Apr 2011

The Wistar Institute, Advaxis enter research collaboration

Advaxis, Inc., the live, attenuated Listeria monocytogenes vaccine company, has entered into a research collaboration with the laboratory of Ellen Puré, Ph.D., professor/associate vice president for Academic Affairs at The Wistar Institute.

15 Apr 2011

Catherine Zeta Jones treated for bipolar disorder

Catherine Zeta Jones – the 41-year-old Welsh actor checked into a day clinic in Connecticut for five days earlier this month for the treatment of bipolar disorder. “After dealing with the stress of the past year, Catherine made the decision to check in to a mental health facility for a brief stay to treat her Bipolar II Disorder,” said publicist Cece Yorke said in a statement adding, “She's feeling great and looking forward to starting work this week on her two upcoming films.”

13 Apr 2011

Study finds SAVI applicator for breast brachytherapy safe for women with breast implants

The SAVI® applicator for breast brachytherapy was used to safely deliver post-lumpectomy radiation therapy to a woman with breast implants, according to a newly published paper in a peer-reviewed journal. The case study showed that SAVI produced an "optimal" clinical outcome and "excellent cosmetic results that pleased the patient," wrote the authors.

12 Apr 2011

Yissum announces successful Docetaxel pre-clinical data in cancer

Yissum Research Development Company Ltd., the technology transfer company of the Hebrew University of Jerusalem, announced today successful pre-clinical data of oral delivery of Docetaxel, an anti-cancer drug, utilizing a novel nanotechnology platform.

12 Apr 2011

Positive outcomes from Gamma Knife Radiosurgery in posterior fossa meningiomas

Meningiomas are the most common benign intracranial tumors, and in individuals ages 35 and older, the most common type of brain tumor diagnosed. They most often occur in people between the ages of 40 and 70.

12 Apr 2011

Positive results from ULCA's Phase 1 dendritic cell vaccine trial in glioblastoma

A novel brain tumor vaccine clinical trial study demonstrates a longer survival time in patients with glioblastoma, according to findings being presented at the 79th Annual Scientific Meeting of the American Association of Neurological Surgeons in Denver.

12 Apr 2011

Alternative mechanism through which tumor cells become invasive

Researchers at the Hebrew University of Jerusalem have discovered a previously unknown mechanism whereby tumor cells invade normal tissues, spreading cancer through various organs.

12 Apr 2011

Hypericin may treat recurrent malignant brain tumors

Researchers have found that a synthetic version of hypericin, a compound naturally found in St. John's wort, may be a promising treatment for patients with recurrent malignant brain tumors. Their findings were published online on March 31, 2011 in the journal Cancer.

12 Apr 2011

Pharmacological manipulation of DKK1, DKK2 can treat various vascular diseases

Angiogenesis, the development of new blood vessels, is required during embryonic development and wound healing, as well as during disease processes such as tumor growth. The signals that direct angiogensis are incompletely understood, but could represent novel targets for the development of therapies that promote or inhibit this process.

12 Apr 2011

Researchers discover new mechanism underlying esophageal cancer

A gene thought to be associated with cancer development can be a tumor suppressor gene in mice, researchers have discovered. Understanding which genes are involved in spreading cancer could lead to future therapies.

12 Apr 2011

Researchers discover new cancer stem cells in breast tissue

Whitehead Institute researchers have discovered that a differentiated cell type found in breast tissue can spontaneously convert to a stem-cell-like state, the first time such behavior has been observed in mammalian cells.

12 Apr 2011

Novelos Therapeutics acquires Cellectar

Novelos Therapeutics, Inc., a pharmaceutical company developing novel drugs for treatment and diagnosis of cancer, today announced that it has completed its acquisition of Cellectar, Inc., a Wisconsin-based drug development company, in a stock-for-stock transaction.

12 Apr 2011

Research on rare cancers

A cancer diagnosis can be a life-changing event. Many questions arise, with one of the first being, "Where should I be treated?" Patients diagnosed with rare cancers may have difficulty finding a physician knowledgeable in treating their type of cancer.

11 Apr 2011

CINJ experts to comment on vaccine therapy and biomedical informatics

April marks National Cancer Control Awareness Month, which focuses on the importance of prevention, treatment, and research. Making significant contributions in all of these areas is The Cancer Institute of New Jersey, one of the nation's 40 Comprehensive Cancer Centers as designated by the National Cancer Institute and the only such center in New Jersey.

11 Apr 2011

New experimental drug can help treat peripheral neuropathy in cancer patients

Although oncologists have made great strides in many aspects of cancer treatment, one area that has remained very difficult to treat is peripheral neuropathy, namely pain that can be caused by the cancer or by its treatment.

11 Apr 2011

Neurosurgeons to present techniques and discuss surgical approaches at AANS meeting

Neurosurgeons from NYU Langone Medical Center will present techniques and discuss surgical approaches and applications of technology at the annual meeting of the American Association of Neurological Surgeons, held April 9-13, 2011 at the Colorado Convention Center in Denver.

11 Apr 2011

Polaris' ADI-PEG 20 exhibits potential against AML, GBM and bladder cancer

Polaris Group announced today that data from preclinical studies suggest ADI-PEG 20, the Company's pegylated arginine deiminase therapeutic, may be effective in treating acute myeloid leukemia (AML), glioblastoma multiforme (GBM) and bladder cancer.

8 Apr 2011

Gene expression changes in prostate tissue surrounding cancer lesions may allow prostate cancer diagnosis

Researchers have found that gene expression changes in prostate tissue surrounding cancer lesions may allow diagnosis of prostate cancer even if no cancer cells are present in biopsy tissue, according to study results published in Cancer Research, a journal of the American Association for Cancer Research.

8 Apr 2011

New Clinical Practice Guideline for evaluation and treatment of pituitary incidentalomas

Today, The Endocrine Society released a new Clinical Practice Guideline (CPG) for the evaluation and treatment of pituitary incidentalomas. The CPG is published in the April 2011 issue of the Journal of Clinical Endocrinology & Metabolism (JCEM), a publication of The Endocrine Society.

8 Apr 2011