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Antidepressant treatments increase risk of weight gain, study finds

Researchers in the School of Population Health & Environmental Sciences have found that patients prescribed any of the 12 most commonly used antidepressants were 21% more likely to experience an episode of gain weight than those not taking the drugs, after adjusting for other factors which might affect this result.

24 May 2018

Scientists uncover the cause of insulin resistance in obesity

A team of international researchers has identified a pathway by which obesity results in reduced insulin sensitivity.

24 May 2018

Scientists report new strategy for fighting bacteria

Antimicrobial resistance is a major medical problem worldwide, impacting both human health and economic well-being.

24 May 2018

CU research sheds light on liver disease caused by intravenous nutrition

Research by physician-scientists at the University of Colorado Anschutz Medical Campus offers hope for improved quality of life for people who rely on intravenous nutrition due to intestinal damage.

24 May 2018

Drugmakers blamed for blocking generics have milked prices and cost U.S. billions

Makers of brand-name drugs called out by the Trump administration for potentially stalling generic competition have hiked their prices by double-digit percentages since 2012 and cost Medicare and Medicaid nearly $12 billion in 2016, a Kaiser Health News analysis has found.

23 May 2018

Mapping the Genes Responsible for Pluripotency

Dr. Atilgan Yilmaz and his team have developed a method by which they can produce haploid human embryonic stem cells from oocytes. They combined this technique with CRISPR-Cas9 to generate an atlas of the genome, containing the functions of over 18,000 genes.

23 May 2018

Investigational technology could increase donor organ supply for lung transplants

As many as 80 percent of lungs from organ donors are not used, either because they are not in good enough condition to transplant, or there are doubts about their quality and there is no way to verify their condition.

23 May 2018

Malaria-causing parasite seeks refuge inside the liver to replicate and survive

When the malaria-causing Plasmodium parasite first slips into the human bloodstream, injected by the bite of an infected mosquito, it does not immediately target red blood cells.

23 May 2018

Advanced genetics study of TB bacteria uncovers virulent 'Beijing lineage' strain among young adults

LSTM's Dr Maxine Caws is co-lead investigator on an advanced genetics study published in Nature Genetics(link is external), which has shown that a virulent strain of tuberculosis (TB) has adapted to transmit among young adults in Ho Chi Minh City, Vietnam.

23 May 2018

Celgene to share new and updated data around novel hematological therapies

Celgene Corporation today announced that data from a broad range of early and late stage studies evaluating Celgene investigational agents and investigational uses of marketed products will be presented at the 23rd European Hematology Association annual meeting in Stockholm, Sweden, from June 14-17, 2018.

22 May 2018

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

How can we detect cancer and viruses with high sensitivity? Physical chemist Laura Fabris - an associate professor in the Materials Science and Engineering Department at Rutgers, the State University of New Jersey, and principal investigator of the Fabris NanoBio Group - is addressing this very question.

22 May 2018

Researchers discover link between tuberculosis and Parkinson's disease

The mechanism our immune cells use to clear bacterial infections like tuberculosis (TB) might also be implicated in Parkinson's disease, according to a new collaborative study led by the Francis Crick Institute, Newcastle University and GSK.

22 May 2018

New way of grouping atoms could herald novel materials, drugs and computers

Scientists have found a new way of joining groups of atoms together into shape-changing molecules - opening up the possibility of a new area of chemistry and the development of countless new drugs, microelectronics and materials with novel characteristics.

22 May 2018

PCI along with prescribed drugs better than medication alone for treating for people with heart disease

A non-surgical procedure, called percutaneous coronary intervention, along with prescribed medication, is better than medication alone as initial treatment for people who have the most common form of heart disease, suggests an analysis of an international clinical trial co-led by St. Michael's Hospital.

22 May 2018

Scientists decipher workings of little-understood bacterial riboswitch

In a discovery that points to potential new antibiotic medicines, scientists from Rice University and the University of Michigan have deciphered the workings of a common but little-understood bacterial switch that cuts off protein production before it begins.

22 May 2018

Study sheds new light on sharp rise in fatal drug overdoses in recent years

A study published in the American Journal of Preventive Medicine sheds new light on the sharp rise in fatal drug overdoses in recent years, one of the most severe public health challenges of our time. The study found that the growth in fatal overdoses for non-Hispanic whites aged 22-56 years was sufficiently large to account for the entire growth in mortality rates and years of potential life lost (YPLL) for this population from 1999 to 2015.

22 May 2018

Eczema drug alleviates asthma symptoms and improves lung function

Two new studies of patients with difficult-to-control asthma show that the eczema drug dupilumab alleviates asthma symptoms and improves patients' ability to breathe better than standard therapies.

22 May 2018

Staying up all night, sleeping all day can swiftly impact over 100 proteins in the blood

Staying awake all night and sleeping all day for just a few days can disrupt levels and time of day patterns of more than 100 proteins in the blood, including those that influence blood sugar, energy metabolism, and immune function, according to new University of Colorado Boulder research published in the journal PNAS this week.

22 May 2018

UCI research team uncovers new unexpected mode of neurotransmitter-based communication

Researchers at the University of California, Irvine School of Medicine have discovered the first example of a novel mode of neurotransmitter-based communication.

22 May 2018

Researchers uncover clues to early lung transplant failure

Among organ transplant patients, those receiving new lungs face a higher rate of organ failure and death compared with people undergoing heart, kidney and liver transplants. One of the culprits is inflammation that damages the newly transplanted lung.

22 May 2018