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Pfizer announces Phase 3 study results of LYRICA Oral Solution CV for pediatric epilepsy patients

Pfizer Inc. announced today positive top-line results of a Phase 3 study examining the use of LYRICA® Oral Solution CV as adjunctive therapy for partial onset seizures in pediatric epilepsy patients one month to less than four years of age.

17 May 2018

Researchers discover medulloblastoma subtype that responds to less aggressive therapy

The youngest patients with the brain tumor medulloblastoma are among the most challenging because their rapidly developing brains limit treatment options.

17 May 2018

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Alexo Therapeutics, a clinical-stage immuno-oncology company developing therapies to block the CD47 checkpoint mechanism, today announced it has initiated ALX148 combination dosing with targeted antibody therapies in its Phase 1 clinical program in patients with advanced solid tumors and lymphoma.

17 May 2018

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Obsidian Therapeutics, Inc., a biotechnology company dedicated to the development of next-generation cell and gene therapies with pharmacologic operating systems, today announced that the company presented preclinical data on its regulated IL12 and IL15 programs at the Annual Meeting of the American Society of Gene and Cell Therapy in Chicago, IL.

17 May 2018

International study finds viable treatment option for people with mild asthma

A large international study led by a Hamilton researcher has found a patient-centric treatment that works for people with mild asthma.

17 May 2018

Scientists disrupt two enzymes to shrink cancer cells

Before cell division, the long strings of the cell's DNA are wrapped tightly into the structures we know as chromosomes. This protects the cell's genetic material from physical and chemical damage.

17 May 2018

New mode of proton therapy for lung cancer developed by Beaumont shows promising results

"Beaumont researchers have invented a new mode of proton therapy for lung cancer," said Peyman Kabolizadeh, M.D., Ph.D., clinical director, Beaumont Proton Therapy Center in Royal Oak.

17 May 2018

Researcher develops small molecules that inhibit derailment of gene expression in cancer

Not everyone person who has a "cancer gene" will inevitably develop this disease in their lifetime. Thanks to a new area of research called epigenetics, we now know that many genes are only read under certain circumstances.

17 May 2018

ECDC whole genome sequencing study helps understand prevalence of drug-resistant gonorrhea

Can whole genome sequencing illustrate changes in drug susceptibility of gonorrhoea to antimicrobials used for treatment and so help to define more effective treatment regimens? The first study of this kind within an international surveillance programme for sexually transmitted infections shows distribution of drug-resistant gonorrhoea strains across Europe.

17 May 2018

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

The U.S. Food and Drug Administration today approved Lucemyra (lofexidine hydrochloride) for the mitigation of withdrawal symptoms to facilitate abrupt discontinuation of opioids in adults.

17 May 2018

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Cleveland Clinic researchers have demonstrated for the first time that lowering blood cholesterol levels could enhance the success of a specific type of T-cell immunotherapy in fighting cancer.

16 May 2018

Musician Huey Lewis's struggle shines spotlight on Ménière's disease

The recent news revealing musician Huey Lewis's struggles with Ménière's disease has shined a spotlight on the neurological disorder. The symptoms, which include unpredictable bouts of dizziness, hearing loss and ringing in the ears, may get progressively worse over time and can greatly interfere with work, driving and daily activities.

16 May 2018

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

In a recent study published in the Journal of Clinical Investigation, Mayo Clinic researchers identified that an FDA drug approved for myelodysplastic syndrome may be useful to treat triple-negative breast cancer, which is one of the most aggressive and lethal types of breast cancer.

16 May 2018

FDA allows KU Medical Center to begin clinical trial of novel cellular therapy for HR/SR aGvHD

The University of Kansas Medical Center announced that the U.S. Food and Drug Administration has cleared it to begin a first-in-human clinical trial of MSCTC-0010 in patients with de novo high-risk acute or steroid-refractory acute graft-versus-host disease (HR/SR aGvHD).

16 May 2018

Combination therapies targeting different cell types may be effective at treating colon cancer

Researchers in Germany have discovered that colon cancers are often resistant to existing drug treatments because they are composed of two different cell types that can replace each other when one cell type is killed.

16 May 2018

FDA clears Turnstone Biologics' IND for immunotherapy targeting HPV positive solid tumors

Turnstone Biologics today announced it has received U.S. Food and Drug Administration clearance of its Investigational New Drug Application for MG1-HPV for the treatment of patients with human papillomavirus positive solid tumors.

16 May 2018

VA health care study: Many prostate cancer patients choose active surveillance over immediate therapy

Record numbers of American veterans diagnosed with non-aggressive prostate cancer are heeding the advice of international medical experts and opting out of immediate surgery or radiation to treat their cancer.

16 May 2018

MDMA appears to help in treating PTSD patients

When lasting trauma is caused by callous acts of violence, the key to recovery can be making meaning out of meaninglessness.

16 May 2018

Post-menopausal Conversations: Why You Should Talk to Your Clinician

Many post-menopausal women shy away from discussing their sexual health with their physician, often because they believe it is a natural part of life and they should suffer. Dr. Mickey Karram wants to change that, by encouraging women to talk to their physician about the treatments available to them.

16 May 2018

Study finds distinct exhausted T cells that could have implications for fighting different diseases

The battle between the human immune system and long-term, persisting infections and other chronic diseases such as cancer results in a prolonged stalemate

16 May 2018

Therapy News and Research

Pfizer announces Phase 3 study results of LYRICA Oral Solution CV for pediatric epilepsy patients

Researchers discover medulloblastoma subtype that responds to less aggressive therapy

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

International study finds viable treatment option for people with mild asthma

Scientists disrupt two enzymes to shrink cancer cells

New mode of proton therapy for lung cancer developed by Beaumont shows promising results

Researcher develops small molecules that inhibit derailment of gene expression in cancer

ECDC whole genome sequencing study helps understand prevalence of drug-resistant gonorrhea

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Musician Huey Lewis's struggle shines spotlight on Ménière's disease

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

FDA allows KU Medical Center to begin clinical trial of novel cellular therapy for HR/SR aGvHD

Combination therapies targeting different cell types may be effective at treating colon cancer

FDA clears Turnstone Biologics' IND for immunotherapy targeting HPV positive solid tumors

VA health care study: Many prostate cancer patients choose active surveillance over immediate therapy

MDMA appears to help in treating PTSD patients

Post-menopausal Conversations: Why You Should Talk to Your Clinician

Study finds distinct exhausted T cells that could have implications for fighting different diseases

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

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