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Self-adhering chest patch may better detect common heart rhythm disorder than usual care

For people at heightened risk for atrial fibrillation —a common heart rhythm disorder that also carries a high risk of stroke—wearing a self-adhering chest patch that records heart patterns may better detect the condition and facilitate more timely treatment than relying on usual care, according to one-year data being presented at the American College of Cardiology's 67th Annual Scientific Session.

12 Mar 2018

Inhaled therapy for heart failure fails to meet either primary or secondary endpoints

Four weeks of treatment with a novel inhaled medication failed to improve exercise capacity, daily activity levels, severity of symptoms or quality of life in patients with a type of heart failure for which no effective treatment options currently exist, according to research presented at the American College of Cardiology's 67th Annual Scientific Session.

12 Mar 2018

Study highlights potential of ASO therapy to treat Fuchs endothelial corneal dystrophy patients

A proof-of-concept study carried out at UCL Institute of Ophthalmology with funding from Fight for Sight has highlighted the potential of a targeted antisense oligonucleotide therapy to treat Fuchs endothelial corneal dystrophy patients with a mutation in the TCF4 gene.

12 Mar 2018

Wearable defibrillator reduces overall mortality, but not sudden cardiac death

Wearing a lightweight vest equipped with a cardioverter defibrillator that detects abnormal heart rhythms in addition to taking recommended medications is associated with a reduction in the likelihood of dying during the first 90 days following a heart attack in people whose heart function was also impaired, according to a study presented at the American College of Cardiology's 67th Annual Scientific Session.

12 Mar 2018

PCSK9 inhibitor reduces cardiovascular events in ACS patients with high cholesterol

Among patients with persistently high cholesterol despite high-intensity statin therapy, the proprotein convertase subtilisin-kexin 9 (PCSK9) inhibitor alirocumab reduced rates of major adverse cardiovascular events by 15 percent compared with placebo, in a study presented at the American College of Cardiology's 67th Annual Scientific Session.

12 Mar 2018

Researchers develop new method to increase life span of donated brain tissue samples

Researchers at Lund University in Sweden have developed a method that enables them to use donated brain tissue from people with epilepsy for 48 hours. Previously, the researchers only had 12 hours to test new treatments before the structure of the cells started to break down. The research has now been published in the journal Scientific Reports.

9 Mar 2018

Gut microbes linked to severity of intestinal parasitic worm infections

A new study indicates that the kinds of microbes living in the gut influence the severity and recurrence of parasitic worm infections in developing countries.

9 Mar 2018

Early microstructural changes can help predict long-term recovery from spinal cord injury

A trauma to the spinal cord, quickly leads to a progressive loss of nerve tissue. This not only affects the injured area, but over time affects also other parts of the spinal cord and even the brain.

9 Mar 2018

Internet-based depression treatment has no long-term protective effect, study shows

The long-term outcome of a randomized controlled trial on depression treated with psychotherapy via internet is presented in the current issue of Psychotherapy and Psychosomatics.

9 Mar 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

How Medicaid became a go-to funder for schools

Gerardo Alejandrez used to punch classmates, throw chairs and curse at his teachers, conduct that forced him to switch from school to school. "I had a lot of anger issues," the 16-year-old said recently.

9 Mar 2018

Adolescent, young adult cancer survivors have stronger social networks than non-cancer peers

Survivors of adolescent and young adult cancer often have stronger social networks than their non-cancer peers, according to St. Jude Children's Research Hospital researchers, who hope to translate that support into better lives for the nation's growing population of cancer survivors.

9 Mar 2018

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Scientists at The Scripps Research Institute have now shown a path to developing treatments for disease subtype CMT2D.

8 Mar 2018

Research reports increased caregiver strain when patients receive heart pumping device

When heart failure patients receive a heart pumping device known as a left ventricular assist device (LVAD), their caregivers seem to suffer, too - at least initially, according to research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

8 Mar 2018

New study examines origin of cryptococcosis within the central nervous system

A particular fungal infection is responsible for more than 220,000 cases of cryptococcosis worldwide each year in people with HIV and AIDS, with nearly 181,000 of those resulting in death.

8 Mar 2018

Research reveals neuroprotective mechanisms of gene and cell medications for spinal cord injuries

A joint paper with Kazan State Medical University appeared in Stem Cells International. The research was based at the Gene and Cell Technologies Lab of Kazan University.

8 Mar 2018

Scientists discover 36 previously unknown genes implicated in heart failure

One in four deaths in the United States each year are due to heart disease, according to the Centers for Disease Control and Prevention. It's the leading killer of both men and women, but the disease's genetic complexity makes it difficult to treat.

8 Mar 2018

Researchers identify new mechanism to disrupt HIV latency

HIV, the virus that causes AIDS, has a secret life. Though anti-retroviral therapy can reduce its numbers, the virus can hide and avoid both treatments and the body's immune response.

8 Mar 2018

Scientists discover connection between breast cancer protein and pediatric cancer

Scientists with the Greehey Children's Cancer Research Institute at UT Health San Antonio have discovered a surprising connection between a breast cancer protein, BRCA1, and a pediatric cancer called Ewing sarcoma.

8 Mar 2018

Innovative psychotherapeutic treatment protocol for obsessive-compulsive disorders

An innovative psychotherapeutic treatment protocol is presented in the current issue of Psychotherapy and Psychosomatics. Exposure and ritual prevention (ERP) treats obsessive-compulsive disorder (OCD), but only some patients achieve minimal symptoms at treatment completion.

8 Mar 2018

Therapy News and Research

Self-adhering chest patch may better detect common heart rhythm disorder than usual care

Inhaled therapy for heart failure fails to meet either primary or secondary endpoints

Study highlights potential of ASO therapy to treat Fuchs endothelial corneal dystrophy patients

Wearable defibrillator reduces overall mortality, but not sudden cardiac death

PCSK9 inhibitor reduces cardiovascular events in ACS patients with high cholesterol

Researchers develop new method to increase life span of donated brain tissue samples

Gut microbes linked to severity of intestinal parasitic worm infections

Early microstructural changes can help predict long-term recovery from spinal cord injury

Internet-based depression treatment has no long-term protective effect, study shows

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

How Medicaid became a go-to funder for schools

Adolescent, young adult cancer survivors have stronger social networks than non-cancer peers

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Research reports increased caregiver strain when patients receive heart pumping device

New study examines origin of cryptococcosis within the central nervous system

Research reveals neuroprotective mechanisms of gene and cell medications for spinal cord injuries

Scientists discover 36 previously unknown genes implicated in heart failure

Researchers identify new mechanism to disrupt HIV latency

Scientists discover connection between breast cancer protein and pediatric cancer

Innovative psychotherapeutic treatment protocol for obsessive-compulsive disorders

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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