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Scientists highlight advances and uses of organoids in gastroenterology and hepatology

One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo.

4 Jun 2019

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

In a study led by UCLA investigators, treatment with the immunotherapy drug pembrolizumab helped more than 15% of people with advanced non-small cell lung cancer live for at least five years - and 25% of patients whose tumor cells had a specific protein lived at least that long.

3 Jun 2019

African rodents immune to pain caused by wasabi

A new report in Science provides the first evidence of a mammal - the highveld mole-rat - being immune to pain from exposure to allyl isothiocyanate, or AITC, the active ingredient of wasabi.

31 May 2019

Cancer researchers discover new functions for common oncogene MYC

Cancer researchers have discovered surprising new functions for a protein called MYC, a powerful oncogene that is estimated to drive the development of almost half a million new cancer cases in the US every year.

30 May 2019

Expedeon announces addition of CaptSure DIY ELISA to immunoassay product portfolio

CaptSure DIY ELISA will complement Expedeon AG’s product offering, as the Company announced today. The technology was developed by TGR BioSciences, which was acquired by Expedeon in May 2018.

29 May 2019

Provocation of obsessive thoughts induces physiological brain changes in 64-year-old man with OCD

Thoughts that lead to compulsive behavior in obsessive-compulsive disorder (OCD) correspond with physiological changes in the brain, according to a new case study. The article is published ahead of print in the Journal of Neurophysiology.

28 May 2019

Researchers discover unexpected survival mechanism of a subset of cancer cells

Embedded at the end of chromosomes are structures called "telomeres" that in normal cells become shorter as cells divide. As the shortening progresses it triggers cell proliferation arrest or death. Cancer cells adopt different strategies to overcome this control mechanism that keeps track of the number of times that a cell has divided.

28 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Mites and ticks are part of the same evolutionary line, research shows

Scientists from the University of Bristol and the Natural History Museum in London have reconstructed the evolutionary history of the chelicerates, the mega-diverse group of 110,000 arthropods that includes spiders, scorpions, mites and ticks.

27 May 2019

New neurons continue to form in old age, even in people with Alzheimer's disease

In a new study from the University of Illinois at Chicago, researchers examining post-mortem brain tissue from people ages 79 to 99 found that new neurons continue to form well into old age.

25 May 2019

Cell scientist receives $1.9 million NIH grant to study muscle regeneration

As people age, their muscle regeneration capacity declines in part because they can no longer make enough muscle stem cells to replace damaged tissue.

24 May 2019

Johns Hopkins researchers develop method to map retinal cell development

Johns Hopkins Medicine researchers report they have created a method of mapping how the central nervous system develops by tracking the genes expressed in cells.

24 May 2019

Rutgers-led study pinpoints key gene linked to impaired memory in Down syndrome

Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.

24 May 2019

Experimental noninvasive tool assesses efficacy of stem cell transplantation

Stem-cell based therapies to strengthen the heart muscle and treat other diseases are beginning to show promise in human clinical trials.

23 May 2019

Spatial configuration of the genome is not inherited, but set up during embryogenesis

The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.

23 May 2019

Genetic variation in heart valve cells of developing fetus creates mitral valve prolapse

Genetic variation in heart valve cells of the developing fetus create the blueprint for the later development of mitral valve prolapse, according to the cover story of today's Science Translational Medicine.

23 May 2019

Genetic switch that controls conversion of bad to good fat identified

Fat cells. They are the bane of a dieter's existence, but fat is important. Previous studies showed the subcutaneous white fat cells can transform to brown and beige varieties when exposed to cold stress.

23 May 2019

UW researchers use molecular tethers, chemical 'light sabers' for tissue engineering

Tissue engineering could transform medicine. Instead of waiting for our bodies to regrow or repair damage after an injury or disease, scientists could grow complex, fully functional tissues in a laboratory for transplantation into patients.

22 May 2019

Small molecule drug could be an effective strategy to treat glioblastoma

A team of researchers have published in the International Journal of Oncology that RITA, a drug able to reactivate the oncosuppressor function of p53, could be an effective strategy to treat glioblastoma.

21 May 2019

Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Blood diseases such as leukemia and lymphoma are currently treated with bone marrow transplants -- a transfer of blood stem cells from a healthy person to a patient in need.

21 May 2019

Cell Biology News and Research

Scientists highlight advances and uses of organoids in gastroenterology and hepatology

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

African rodents immune to pain caused by wasabi

Cancer researchers discover new functions for common oncogene MYC

Expedeon announces addition of CaptSure DIY ELISA to immunoassay product portfolio

Provocation of obsessive thoughts induces physiological brain changes in 64-year-old man with OCD

Researchers discover unexpected survival mechanism of a subset of cancer cells

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Mites and ticks are part of the same evolutionary line, research shows

New neurons continue to form in old age, even in people with Alzheimer's disease

Cell scientist receives $1.9 million NIH grant to study muscle regeneration

Johns Hopkins researchers develop method to map retinal cell development

Rutgers-led study pinpoints key gene linked to impaired memory in Down syndrome

Experimental noninvasive tool assesses efficacy of stem cell transplantation

Spatial configuration of the genome is not inherited, but set up during embryogenesis

Genetic variation in heart valve cells of developing fetus creates mitral valve prolapse

Genetic switch that controls conversion of bad to good fat identified

UW researchers use molecular tethers, chemical 'light sabers' for tissue engineering

Small molecule drug could be an effective strategy to treat glioblastoma

Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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