Lymph Nodes News and Research

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FDA approves gene test to detect spread of breast cancer into lymph nodes

Veridex, LLC, a Johnson & Johnson company, has announced U.S. Food and Drug Administration (FDA) approval of the first intra-operative and gene-based test to detect the spread of breast cancer into the lymph nodes.

17 Jul 2007

FDA approves new test which detects breast cancer spread

The Food and Drug Administration (FDA) in the U.S. has given approval for a new test to be used which can detect if breast cancer has spread to a patient's lymph nodes.

16 Jul 2007

Paint helps surgeons see where a tumor begins and ends

A tumor paint developed by researchers at Seattle Children's Hospital Research Institute and Fred Hutchinson Cancer Research Center will help surgeons see where a tumor begins and ends more precisely by illuminating the cancerous cells.

16 Jul 2007

Nodal status is best predictor of outcome after neoadjuvant therapy for esophageal cancer

The number of lymph nodes that contain evidence of cancer is the best predictor of the effectiveness of adding chemotherapy and radiation to a treatment plan prior to surgery in individuals with oesophageal cancer, according to a study published last month in the Annals of Surgery.

16 Jul 2007

Kaposi sarcoma tumors arise independently from multiple cells

Kaposi sarcoma is unique among cancers because most tumors grow from a small number of different cells, whereas nearly all other cancers arise from a single cell, according to a study published online July 10 in the Journal of the National Cancer Institute.

11 Jul 2007

Sentinel lymph node biopsy is associated with breast cancer rates

The incidence of some early stage metastatic breast cancers is increasing, but this finding is likely explained by changes in clinical practice, according to a study published online June 26 in the Journal of the National Cancer Institute.

27 Jun 2007

Bristol-Myers Squibb granted NDA for ixabepilone

Bristol-Myers Squibb has announced that the U.S. Food and Drug Administration (FDA) has accepted, for filing and review, the New Drug Application (NDA) for the investigational compound ixabepilone, an epothilone B analog.

20 Jun 2007

How 'memory' T cells protect the body from viral diseases

A scientific discovery by Fox Chase Cancer Center researchers helps explain how 'memory' T cells protect the body from viral diseases.

19 Jun 2007

Type of insurance coverage linked to more advanced cancers

Two new studies find the uninsured and people with certain types of public health insurance are more likely to be diagnosed with more advanced cancer compared to those with private insurance.

16 Jun 2007

Quantum dots outline brain tumors for surgical removal

Although surgical removal of a tumor can be the most effective way of treating brain cancer, neurosurgeons are often faced with the dilemma of determining the exact border between a tumor and the healthy tissue that surrounds it.

14 Jun 2007

New bacterium discovered, Bartonella rochalimae

A close cousin of the bacterium that debilitated thousands of World War I soldiers has been isolated at UCSF from a patient who had been on an international vacation.

8 Jun 2007

Underuse of pancreatectomy in the United States

More than half of eligible patients with operable, early-stage pancreatic cancer don't undergo potentially life-extending surgery, suggests a study published online in the Annals of Surgery, published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

8 Jun 2007

Angiogenesis gene polymorphisms predict tumor recurrence in stage II and III colon cancer

Researchers at the University of Southern California (USC) have identified specific molecular markers that may help to predict tumor recurrence in stage II and III colon cancer patients.

8 Jun 2007

Blocking the action of beta1-integrin to treat cancer

Targeting the function of a protein known as beta1-integrin might represent a novel approach to cancer treatment, according to a paper published online in the EMBO Journal.

8 Jun 2007

Diet may influence survival after treatment for stage III colon cancer

Patients with stage III colon cancer who have undergone surgery and chemotherapy with the goal of cure may have a higher risk of relapsing and dying early if they follow a predominantly Western diet of red meat, fatty foods, refined grains, and desserts, according to research led by investigators at Dana-Farber Cancer Institute in Boston.

5 Jun 2007

Benefits of Herceptin are lasting

An updated analysis of two large randomized clinical trials has found that breast cancer patients who received the monoclonal antibody trastuzumab (Herceptin) along with chemotherapy are living longer and with less risk of recurrent disease, compared to patients treated with chemotherapy alone.

5 Jun 2007

Natalizumab returns to market

Just months after receiving FDA approval, natalizumab, a medication for the treatment of multiple sclerosis (MS) and other inflammatory disorders, was voluntarily withdrawn by its manufacturers after three patients developed a brain infection known as Progressive Multifocal Leukoencephalopathy (PML).

28 May 2007

Heart-assist device gives Culver City man a better quality of life

Mark Heiner of Culver City reads books, paints artistically, takes walks and does laundry – activities that would be considered routine except for the fact that a four-pound disk implanted in his abdominal cavity is keeping his blood flowing.

28 May 2007

Scientists develop method to track immune system enzyme in live animals

Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity and B cell tumor development.

18 May 2007

PET-CT is better for early detection of muscular lymphoma than CT alone

For the study, PET-CT was used to image 305 patients with lymphoma. Twelve of these patients had muscular involvement in which 10 were biopsy proven and two were proven by imaging follow-up.

8 May 2007