Neurodegenerative Diseases News and Research

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JPND initiative releases updated global Research and Innovation Strategy

The EU Joint Program - Neurodegenerative Disease Research initiative has launched its updated global Research and Innovation Strategy, to provide a unified framework for the support of world class research into neurodegenerative diseases.

6 May 2019

Alzheimer's disease may be caused by infectious proteins called prions

Scientists have used advanced laboratory assays to show that high levels of prions are implicated in early-onset Alzheimer’s disease.

2 May 2019

New type of dementia is '100 times more common' than ALS

Physicians have defined a new form of dementia that may be more common than Alzheimer’s disease. The condition, named LATE, affects a different part of the brain.

1 May 2019

A poor sense of smell increases your risk of dying early, but scientists don’t know why

Researchers have found that a poor sense of smell during older age is be associated with an increased likelihood of dying within the next ten years. However, they can’t explain why.

30 Apr 2019

BUSM receives $4.9 million MLSC grant to accelerate development of new brain imaging techniques

Boston University School of Medicine today announced that it had received a $4.9 million grant from the Massachusetts Life Sciences Center to create a state-of the-art facility to accelerate development of novel brain imaging techniques to track subtle changes in the brain after neurotrauma.

30 Apr 2019

Veterans, active-duty service members with PTSD and mTBI have larger amygdalas, finds study

A new study finds that veterans and active-duty service members with combat-related PTSD and mild traumatic brain injury had larger amygdalas--the region of the brain that processes such emotions as fear, anxiety, and aggression--than those with only brain injuries.

30 Apr 2019

Stem cells in hair follicles have potential to regenerate myelin sheath that coats neurons

A subset of the stem cells in hair follicles have the potential to regenerate the coating that insulates neurons in mice, reports Thomas Hornyak of the VA Maryland Health Care System and the University of Maryland School of Medicine and colleagues, in a new study published 24th April in PLOS Genetics.

25 Apr 2019

New chemical synthesis strategy leads to identification of novel, simpler derivatives

A new chemical synthesis strategy to harvest the rich information found in natural products -- organic compounds isolated from natural sources -- has led to the identification of novel, simpler derivatives with potential to selectively protect neurons, important for neurodegenerative diseases like Alzheimer's disease, or to prevent the immune system from rejecting organ transplants, according to a Baylor University-led study.

25 Apr 2019

Integrator complex proteins are crucial for healthy brain development in fruit flies, study finds

A study by Duke-NUS Medical School has found that members of the multiprotein 'Integrator complex', known for its role in gene regulation, are crucial for healthy brain development in fruit flies.

24 Apr 2019

Study provides evidence that blood tests can detect Alzheimer’s risk

A new study confirms that a simple blood test can reveal whether there is accelerating nerve cell damage in the brain.

23 Apr 2019

Microglia play vital role in regulating neuroinflammation, research shows

A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the central nervous system--including the retina of the eye--serve as "gatekeepers," or biosensors and facilitators, of neuroinflammation in a preclinical model of autoimmune uveitis.

23 Apr 2019

Research uncovers critical RNA processing aberrations in ALS and FTD

Research by a Barrow Neurological Center scientist on mechanisms of dysfunctional RNA processing in ALS and frontal temporal dementia was published in the April issue of Acta Neuropathologica.

21 Apr 2019

Drug that treats high blood pressure shows promise against neurodegenerative diseases

A prescribed drug to treat high blood pressure has shown promise against conditions such as Parkinson's, Huntington's and forms of dementia in studies carried out in mice and zebrafish at the University of Cambridge.

19 Apr 2019

Framingham Heart Study receives $38 million for the next six years

The Framingham Heart Study, the nation's longest running cohort study with longitudinal analysis of cardiovascular disease, has been renewed for an additional six years and $38 million dollars from the National Heart, Lung, and Blood Institute.

16 Apr 2019

Scientists investigate processes that lead to neuronal death in ALS patients

Amyotrophic lateral sclerosis is an incurable disease of the central nervous system. In most cases, ALS is fatal within a short period following diagnosis.

15 Apr 2019

Scientists develop technique to clear abnormal tau protein from human neurons

Harnessing a probe used to image the brain in diagnosing Alzheimer's disease and related forms of dementia, scientists at Dana-Farber Cancer Institute and Massachusetts General Hospital have successfully cleared patient-derived brain cells of an abnormal protein associated with dementia and other neurogenerative disorders.

10 Apr 2019

Study suggests novel therapeutic strategy for ALS

In a study published online in Brain on April 1, researchers from Dr. XU Jin's lab at the Institute of Neuroscience of the Chinese Academy of Sciences and their collaborators revealed a new cellular mechanism for amyotrophic lateral sclerosis, suggested a novel therapeutic strategy targeting the RNA degradation pathway, and identified an asthma drug as a potential medication for ALS.

9 Apr 2019

Study reveals how higher educational attainment may stave off cognitive decline

Prefrontal brain regions linked to higher educational attainment are characterized by increased expression of genes involved in neurotransmission and immunity, finds a study of healthy older adults published in JNeurosci.

From Society for Neuroscience 9 Apr 2019

PET images of microglial activation levels could better predict Alzheimer's disease progression

Researchers have discovered a way to better predict progression of Alzheimer's disease. By imaging microglial activation levels with positron emission tomography, researchers were able to better predict progression of the disease than with beta-amyloid PET imaging, according to a study published in the April issue of the Journal of Nuclear Medicine.

4 Apr 2019

Transplantation of bone marrow-derived EPCs slows ALS disease progression

Transplantation of human bone marrow-derived endothelial progenitor cells into mice mimicking symptoms of amyotrophic lateral sclerosis (ALS) helped mor, University of South Florida researchers report.

3 Apr 2019

Neurodegenerative Diseases News and Research

JPND initiative releases updated global Research and Innovation Strategy

Alzheimer's disease may be caused by infectious proteins called prions

New type of dementia is '100 times more common' than ALS

A poor sense of smell increases your risk of dying early, but scientists don’t know why

BUSM receives $4.9 million MLSC grant to accelerate development of new brain imaging techniques

Veterans, active-duty service members with PTSD and mTBI have larger amygdalas, finds study

Stem cells in hair follicles have potential to regenerate myelin sheath that coats neurons

New chemical synthesis strategy leads to identification of novel, simpler derivatives

Integrator complex proteins are crucial for healthy brain development in fruit flies, study finds

Study provides evidence that blood tests can detect Alzheimer’s risk

Microglia play vital role in regulating neuroinflammation, research shows

Research uncovers critical RNA processing aberrations in ALS and FTD

Drug that treats high blood pressure shows promise against neurodegenerative diseases

Framingham Heart Study receives $38 million for the next six years

Scientists investigate processes that lead to neuronal death in ALS patients

Scientists develop technique to clear abnormal tau protein from human neurons

Study suggests novel therapeutic strategy for ALS

Study reveals how higher educational attainment may stave off cognitive decline

PET images of microglial activation levels could better predict Alzheimer's disease progression

Transplantation of bone marrow-derived EPCs slows ALS disease progression

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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